Neurology:额颞叶痴呆者中,白质高信号病变和神经退行性变密切相关

2021-04-29 Freemann MedSci原创

额颞叶痴呆者中,白质高信号病变和神经退行性变密切相关

白质高信号病变(WMH)是T2加权MRI上的高强化信号区域。WMH随着年龄的增长越来越常见,并反映小血管疾病负担。WMH体积与认知障碍和痴呆的风险有关,包括阿尔茨海默病(AD)。然而,重要的是,阿尔茨海默病的WMH可能是由疾病病理而非血管变化引起的,据报道,在脑萎缩和tau沉积增加的区域,WMH会增加。 在额颞叶痴呆症( behavioral-variant FTD)中,只有少数的队列和病例研究,而且只在FTD的遗传病例中进行。特别是,与对照组相比,丙种球蛋白(GRN)突变携带者的WMH体积增加,但在C9orf72扩增和MAPT突变的病例中没有报道。目前,对WMH的研究主要集中在WMH的总负担上。许多研究没有探讨与疾病和血管因素的关系,并将认知调查限制在选择性的领域。这些局限性因使用准确度和可靠性较低的视觉评分量表和粗略的解剖分区而变得更加复杂。 藉此,澳大利亚新南威尔士大学的Katharine Huynh等人,全面地描述FTD和AD的WMH特征。探究了全脑WMH体积和分布与脑萎缩、疾病严重程度、血管风险和认知能力的关系。 提出假设:(1)患者的WMH体积比对照组大,在不同的疾病之间没

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (7)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1677157, encodeId=634816e715720, content=<a href='/topic/show?id=e2f4e4588e9' target=_blank style='color:#2F92EE;'>#神经退行性变#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=74588, encryptionId=e2f4e4588e9, topicName=神经退行性变)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a3cc27444881, createdName=liuyiping, createdTime=Thu Dec 09 03:50:36 CST 2021, time=2021-12-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1765862, encodeId=2b7b1e658621d, content=<a href='/topic/show?id=252ae1803a3' target=_blank style='color:#2F92EE;'>#白质#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71803, encryptionId=252ae1803a3, topicName=白质)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=778d36, createdName=柳叶一刀, createdTime=Wed Sep 15 13:50:36 CST 2021, time=2021-09-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1950827, encodeId=2182195082e42, content=<a href='/topic/show?id=20101021e97e' target=_blank style='color:#2F92EE;'>#高信号#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102179, encryptionId=20101021e97e, topicName=高信号)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=08e4137, createdName=meichuangyi, createdTime=Thu Jul 15 17:50:36 CST 2021, time=2021-07-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1957189, encodeId=d8fa195e18954, content=<a href='/topic/show?id=5879e458629' target=_blank style='color:#2F92EE;'>#神经退行#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=74586, encryptionId=5879e458629, topicName=神经退行)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=33b92500139, createdName=12498b37m72暂无昵称, createdTime=Wed Jun 09 18:50:36 CST 2021, time=2021-06-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2001317, encodeId=1c08200131ee6, content=<a href='/topic/show?id=d5df12695e6' target=_blank style='color:#2F92EE;'>#Neurol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12695, encryptionId=d5df12695e6, topicName=Neurol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8217292, createdName=yinhl1978, createdTime=Sun Oct 24 00:50:36 CST 2021, time=2021-10-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1417575, encodeId=cf87141e5756d, content=<a href='/topic/show?id=c667e181616' target=_blank style='color:#2F92EE;'>#白质高信号#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71816, encryptionId=c667e181616, topicName=白质高信号)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=44693296090, createdName=zhangph, createdTime=Fri Apr 30 20:50:36 CST 2021, time=2021-04-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1048777, encodeId=3c671048e7767, content=老年人痴呆何药可用??, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=junJUN, createdTime=Thu Apr 29 08:50:36 CST 2021, time=2021-04-29, status=1, ipAttribution=)]
  2. [GetPortalCommentsPageByObjectIdResponse(id=1677157, encodeId=634816e715720, content=<a href='/topic/show?id=e2f4e4588e9' target=_blank style='color:#2F92EE;'>#神经退行性变#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=74588, encryptionId=e2f4e4588e9, topicName=神经退行性变)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a3cc27444881, createdName=liuyiping, createdTime=Thu Dec 09 03:50:36 CST 2021, time=2021-12-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1765862, encodeId=2b7b1e658621d, content=<a href='/topic/show?id=252ae1803a3' target=_blank style='color:#2F92EE;'>#白质#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71803, encryptionId=252ae1803a3, topicName=白质)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=778d36, createdName=柳叶一刀, createdTime=Wed Sep 15 13:50:36 CST 2021, time=2021-09-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1950827, encodeId=2182195082e42, content=<a href='/topic/show?id=20101021e97e' target=_blank style='color:#2F92EE;'>#高信号#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102179, encryptionId=20101021e97e, topicName=高信号)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=08e4137, createdName=meichuangyi, createdTime=Thu Jul 15 17:50:36 CST 2021, time=2021-07-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1957189, encodeId=d8fa195e18954, content=<a href='/topic/show?id=5879e458629' target=_blank style='color:#2F92EE;'>#神经退行#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=74586, encryptionId=5879e458629, topicName=神经退行)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=33b92500139, createdName=12498b37m72暂无昵称, createdTime=Wed Jun 09 18:50:36 CST 2021, time=2021-06-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2001317, encodeId=1c08200131ee6, content=<a href='/topic/show?id=d5df12695e6' target=_blank style='color:#2F92EE;'>#Neurol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12695, encryptionId=d5df12695e6, topicName=Neurol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8217292, createdName=yinhl1978, createdTime=Sun Oct 24 00:50:36 CST 2021, time=2021-10-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1417575, encodeId=cf87141e5756d, content=<a href='/topic/show?id=c667e181616' target=_blank style='color:#2F92EE;'>#白质高信号#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71816, encryptionId=c667e181616, topicName=白质高信号)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=44693296090, createdName=zhangph, createdTime=Fri Apr 30 20:50:36 CST 2021, time=2021-04-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1048777, encodeId=3c671048e7767, content=老年人痴呆何药可用??, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=junJUN, createdTime=Thu Apr 29 08:50:36 CST 2021, time=2021-04-29, status=1, ipAttribution=)]
  3. [GetPortalCommentsPageByObjectIdResponse(id=1677157, encodeId=634816e715720, content=<a href='/topic/show?id=e2f4e4588e9' target=_blank style='color:#2F92EE;'>#神经退行性变#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=74588, encryptionId=e2f4e4588e9, topicName=神经退行性变)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a3cc27444881, createdName=liuyiping, createdTime=Thu Dec 09 03:50:36 CST 2021, time=2021-12-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1765862, encodeId=2b7b1e658621d, content=<a href='/topic/show?id=252ae1803a3' target=_blank style='color:#2F92EE;'>#白质#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71803, encryptionId=252ae1803a3, topicName=白质)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=778d36, createdName=柳叶一刀, createdTime=Wed Sep 15 13:50:36 CST 2021, time=2021-09-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1950827, encodeId=2182195082e42, content=<a href='/topic/show?id=20101021e97e' target=_blank style='color:#2F92EE;'>#高信号#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102179, encryptionId=20101021e97e, topicName=高信号)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=08e4137, createdName=meichuangyi, createdTime=Thu Jul 15 17:50:36 CST 2021, time=2021-07-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1957189, encodeId=d8fa195e18954, content=<a href='/topic/show?id=5879e458629' target=_blank style='color:#2F92EE;'>#神经退行#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=74586, encryptionId=5879e458629, topicName=神经退行)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=33b92500139, createdName=12498b37m72暂无昵称, createdTime=Wed Jun 09 18:50:36 CST 2021, time=2021-06-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2001317, encodeId=1c08200131ee6, content=<a href='/topic/show?id=d5df12695e6' target=_blank style='color:#2F92EE;'>#Neurol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12695, encryptionId=d5df12695e6, topicName=Neurol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8217292, createdName=yinhl1978, createdTime=Sun Oct 24 00:50:36 CST 2021, time=2021-10-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1417575, encodeId=cf87141e5756d, content=<a href='/topic/show?id=c667e181616' target=_blank style='color:#2F92EE;'>#白质高信号#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71816, encryptionId=c667e181616, topicName=白质高信号)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=44693296090, createdName=zhangph, createdTime=Fri Apr 30 20:50:36 CST 2021, time=2021-04-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1048777, encodeId=3c671048e7767, content=老年人痴呆何药可用??, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=junJUN, createdTime=Thu Apr 29 08:50:36 CST 2021, time=2021-04-29, status=1, ipAttribution=)]
  4. [GetPortalCommentsPageByObjectIdResponse(id=1677157, encodeId=634816e715720, content=<a href='/topic/show?id=e2f4e4588e9' target=_blank style='color:#2F92EE;'>#神经退行性变#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=74588, encryptionId=e2f4e4588e9, topicName=神经退行性变)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a3cc27444881, createdName=liuyiping, createdTime=Thu Dec 09 03:50:36 CST 2021, time=2021-12-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1765862, encodeId=2b7b1e658621d, content=<a href='/topic/show?id=252ae1803a3' target=_blank style='color:#2F92EE;'>#白质#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71803, encryptionId=252ae1803a3, topicName=白质)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=778d36, createdName=柳叶一刀, createdTime=Wed Sep 15 13:50:36 CST 2021, time=2021-09-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1950827, encodeId=2182195082e42, content=<a href='/topic/show?id=20101021e97e' target=_blank style='color:#2F92EE;'>#高信号#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102179, encryptionId=20101021e97e, topicName=高信号)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=08e4137, createdName=meichuangyi, createdTime=Thu Jul 15 17:50:36 CST 2021, time=2021-07-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1957189, encodeId=d8fa195e18954, content=<a href='/topic/show?id=5879e458629' target=_blank style='color:#2F92EE;'>#神经退行#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=74586, encryptionId=5879e458629, topicName=神经退行)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=33b92500139, createdName=12498b37m72暂无昵称, createdTime=Wed Jun 09 18:50:36 CST 2021, time=2021-06-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2001317, encodeId=1c08200131ee6, content=<a href='/topic/show?id=d5df12695e6' target=_blank style='color:#2F92EE;'>#Neurol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12695, encryptionId=d5df12695e6, topicName=Neurol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8217292, createdName=yinhl1978, createdTime=Sun Oct 24 00:50:36 CST 2021, time=2021-10-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1417575, encodeId=cf87141e5756d, content=<a href='/topic/show?id=c667e181616' target=_blank style='color:#2F92EE;'>#白质高信号#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71816, encryptionId=c667e181616, topicName=白质高信号)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=44693296090, createdName=zhangph, createdTime=Fri Apr 30 20:50:36 CST 2021, time=2021-04-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1048777, encodeId=3c671048e7767, content=老年人痴呆何药可用??, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=junJUN, createdTime=Thu Apr 29 08:50:36 CST 2021, time=2021-04-29, status=1, ipAttribution=)]
  5. [GetPortalCommentsPageByObjectIdResponse(id=1677157, encodeId=634816e715720, content=<a href='/topic/show?id=e2f4e4588e9' target=_blank style='color:#2F92EE;'>#神经退行性变#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=74588, encryptionId=e2f4e4588e9, topicName=神经退行性变)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a3cc27444881, createdName=liuyiping, createdTime=Thu Dec 09 03:50:36 CST 2021, time=2021-12-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1765862, encodeId=2b7b1e658621d, content=<a href='/topic/show?id=252ae1803a3' target=_blank style='color:#2F92EE;'>#白质#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71803, encryptionId=252ae1803a3, topicName=白质)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=778d36, createdName=柳叶一刀, createdTime=Wed Sep 15 13:50:36 CST 2021, time=2021-09-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1950827, encodeId=2182195082e42, content=<a href='/topic/show?id=20101021e97e' target=_blank style='color:#2F92EE;'>#高信号#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102179, encryptionId=20101021e97e, topicName=高信号)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=08e4137, createdName=meichuangyi, createdTime=Thu Jul 15 17:50:36 CST 2021, time=2021-07-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1957189, encodeId=d8fa195e18954, content=<a href='/topic/show?id=5879e458629' target=_blank style='color:#2F92EE;'>#神经退行#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=74586, encryptionId=5879e458629, topicName=神经退行)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=33b92500139, createdName=12498b37m72暂无昵称, createdTime=Wed Jun 09 18:50:36 CST 2021, time=2021-06-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2001317, encodeId=1c08200131ee6, content=<a href='/topic/show?id=d5df12695e6' target=_blank style='color:#2F92EE;'>#Neurol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12695, encryptionId=d5df12695e6, topicName=Neurol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8217292, createdName=yinhl1978, createdTime=Sun Oct 24 00:50:36 CST 2021, time=2021-10-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1417575, encodeId=cf87141e5756d, content=<a href='/topic/show?id=c667e181616' target=_blank style='color:#2F92EE;'>#白质高信号#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71816, encryptionId=c667e181616, topicName=白质高信号)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=44693296090, createdName=zhangph, createdTime=Fri Apr 30 20:50:36 CST 2021, time=2021-04-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1048777, encodeId=3c671048e7767, content=老年人痴呆何药可用??, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=junJUN, createdTime=Thu Apr 29 08:50:36 CST 2021, time=2021-04-29, status=1, ipAttribution=)]
    2021-10-24 yinhl1978
  6. [GetPortalCommentsPageByObjectIdResponse(id=1677157, encodeId=634816e715720, content=<a href='/topic/show?id=e2f4e4588e9' target=_blank style='color:#2F92EE;'>#神经退行性变#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=74588, encryptionId=e2f4e4588e9, topicName=神经退行性变)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a3cc27444881, createdName=liuyiping, createdTime=Thu Dec 09 03:50:36 CST 2021, time=2021-12-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1765862, encodeId=2b7b1e658621d, content=<a href='/topic/show?id=252ae1803a3' target=_blank style='color:#2F92EE;'>#白质#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71803, encryptionId=252ae1803a3, topicName=白质)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=778d36, createdName=柳叶一刀, createdTime=Wed Sep 15 13:50:36 CST 2021, time=2021-09-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1950827, encodeId=2182195082e42, content=<a href='/topic/show?id=20101021e97e' target=_blank style='color:#2F92EE;'>#高信号#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102179, encryptionId=20101021e97e, topicName=高信号)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=08e4137, createdName=meichuangyi, createdTime=Thu Jul 15 17:50:36 CST 2021, time=2021-07-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1957189, encodeId=d8fa195e18954, content=<a href='/topic/show?id=5879e458629' target=_blank style='color:#2F92EE;'>#神经退行#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=74586, encryptionId=5879e458629, topicName=神经退行)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=33b92500139, createdName=12498b37m72暂无昵称, createdTime=Wed Jun 09 18:50:36 CST 2021, time=2021-06-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2001317, encodeId=1c08200131ee6, content=<a href='/topic/show?id=d5df12695e6' target=_blank style='color:#2F92EE;'>#Neurol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12695, encryptionId=d5df12695e6, topicName=Neurol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8217292, createdName=yinhl1978, createdTime=Sun Oct 24 00:50:36 CST 2021, time=2021-10-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1417575, encodeId=cf87141e5756d, content=<a href='/topic/show?id=c667e181616' target=_blank style='color:#2F92EE;'>#白质高信号#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71816, encryptionId=c667e181616, topicName=白质高信号)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=44693296090, createdName=zhangph, createdTime=Fri Apr 30 20:50:36 CST 2021, time=2021-04-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1048777, encodeId=3c671048e7767, content=老年人痴呆何药可用??, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=junJUN, createdTime=Thu Apr 29 08:50:36 CST 2021, time=2021-04-29, status=1, ipAttribution=)]
  7. [GetPortalCommentsPageByObjectIdResponse(id=1677157, encodeId=634816e715720, content=<a href='/topic/show?id=e2f4e4588e9' target=_blank style='color:#2F92EE;'>#神经退行性变#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=74588, encryptionId=e2f4e4588e9, topicName=神经退行性变)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a3cc27444881, createdName=liuyiping, createdTime=Thu Dec 09 03:50:36 CST 2021, time=2021-12-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1765862, encodeId=2b7b1e658621d, content=<a href='/topic/show?id=252ae1803a3' target=_blank style='color:#2F92EE;'>#白质#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71803, encryptionId=252ae1803a3, topicName=白质)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=778d36, createdName=柳叶一刀, createdTime=Wed Sep 15 13:50:36 CST 2021, time=2021-09-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1950827, encodeId=2182195082e42, content=<a href='/topic/show?id=20101021e97e' target=_blank style='color:#2F92EE;'>#高信号#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102179, encryptionId=20101021e97e, topicName=高信号)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=08e4137, createdName=meichuangyi, createdTime=Thu Jul 15 17:50:36 CST 2021, time=2021-07-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1957189, encodeId=d8fa195e18954, content=<a href='/topic/show?id=5879e458629' target=_blank style='color:#2F92EE;'>#神经退行#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=74586, encryptionId=5879e458629, topicName=神经退行)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=33b92500139, createdName=12498b37m72暂无昵称, createdTime=Wed Jun 09 18:50:36 CST 2021, time=2021-06-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2001317, encodeId=1c08200131ee6, content=<a href='/topic/show?id=d5df12695e6' target=_blank style='color:#2F92EE;'>#Neurol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12695, encryptionId=d5df12695e6, topicName=Neurol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8217292, createdName=yinhl1978, createdTime=Sun Oct 24 00:50:36 CST 2021, time=2021-10-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1417575, encodeId=cf87141e5756d, content=<a href='/topic/show?id=c667e181616' target=_blank style='color:#2F92EE;'>#白质高信号#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71816, encryptionId=c667e181616, topicName=白质高信号)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=44693296090, createdName=zhangph, createdTime=Fri Apr 30 20:50:36 CST 2021, time=2021-04-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1048777, encodeId=3c671048e7767, content=老年人痴呆何药可用??, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=junJUN, createdTime=Thu Apr 29 08:50:36 CST 2021, time=2021-04-29, status=1, ipAttribution=)]
    2021-04-29 junJUN

    老年人痴呆何药可用??

    0

相关资讯

JNNP:血浆胶质纤维酸性蛋白和神经丝轻链是衡量原发性进行性失语症患者病情严重程度的指标

语义变异性原发性进行性失语症(svPPA)是一种神经退行性疾病,其特征在于概念知识的丧失,通常表现为单词查找困难,单个单词理解能力受损和颞叶局灶性萎缩。它是额颞叶痴呆(FTD)的一种类型通常与TDP-

Neurology: 血液神经丝轻链蛋白,可有效筛查无症状的额颞叶痴呆

血液神经丝轻链蛋白,可有效筛查无症状的额颞叶痴呆

JNNP: 行为变异性额颞叶痴呆的MRI数据驱动诊断算法

通过计算每个体素处雅可比矩阵的行列式,从非线性变换获得的局部变形被用作组织扩张或萎缩的度量。局部收缩可解释为收缩(如组织萎缩),局部扩张常与心室或脑沟扩大有关。额颞叶痴呆(FTD)的异质性是该病的一个

JNNP:额颞叶痴呆患者颞叶萎缩的独特模式和TARDBP中的I383V变异

额颞叶痴呆(FTD)和肌萎缩侧索硬化(ALS)是一种密切相关的疾病,通过TAR-DNA结合蛋白-43(TDP-43)在病理学和遗传学上相互联系。编码TDP-43的TARDBP中的致病性变体在FTD中的

JNNP:GRN相关额颞叶痴呆生物标志物级联变化的模型研究

染色体17q21上的前粒蛋白(GRN)基因突变是常染色体显性遗传性额颞叶痴呆(FTD)的一个主要原因。大多数突变携带者发展出行为变异的FTD(bvFTD)表型,非流利变异型原发性进行性失语症(nfvP

JNNP:C9orf72相关的额颞叶痴呆和肌萎缩侧索硬化症发病前和血浆microRNA特征

额颞叶性痴呆(FTD)是指中老年患者缓慢出现人格改变、言语障碍及行为异常的痴呆综合征。神经影像学显示额颞叶萎缩。本病是神经变性痴呆较常见的病因,约占全部痴呆病人的1/4。约1/4的额颞叶痴呆病人存在P