AAN围手术期抗血栓药物应用指南

2014-03-18 徐振涛译 医学论坛网

这些有益的指南对脑血管病患者有很好的提示意义,他们应该充分地认识到围手术期风险。 神经病学家经常被要求就有创性治疗的脑血管患者是否继续或停止应用抗血栓药物而拟写规范。由于抗血栓药物不同、患者病情及手术风险不一,制定这种规范比较困难。美国神经病学会承诺最近发布的循证指南更容易掌握。 经过查阅2011年8月份以来的文献,指南制定者发现可供制定关于脑血管病患者围手术期抗血栓药物应用规范的

这些有益的指南对脑血管病患者有很好的提示意义,他们应该充分地认识到围手术期风险。

神经病学家经常被要求就有创性治疗的脑血管患者是否继续或停止应用抗血栓药物而拟写规范。由于抗血栓药物不同、患者病情及手术风险不一,制定这种规范比较困难。美国神经病学会承诺最近发布的循证指南更容易掌握。

经过查阅2011年8月份以来的文献,指南制定者发现可供制定关于脑血管病患者围手术期抗血栓药物应用规范的高质量研究很少。他们根据现有证据建议如下:

·阿司匹林和华法林可继续应用于牙科手术时(A级).

·一些其他相对小的手术时继续应用这些药物可能是安全的。(B级和C级)。

·应用华法林的围手术期患者联合应用肝素的证据,无论支持的还是反对的都很少(U级)。

·联用肝素与单纯应用华法林相比容易增加出血风险(B级)。

·应该告知患者停用阿司匹林或华法林增加中风的风险,特别是应用超过7天者(B级)。

点评

这些指南突显了缺乏关于围手术期抗血栓药物应用最佳方案的有力证据,特别是对脑血管病患者。当然,它以现有证据综合分析为基础,也包含很多有益的建议,它会帮助神经科医师给患者一致的建议。这个指南也提醒神经科医师,要确保他们的脑血管患者在行有创治疗知情同意前被充分告知围手术期中风及出血的风险。它在决定这些高风险患者每个手术必要性时没有强调多学科讨论的重要性。 


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    2014-03-20 bluefate123
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    2014-03-20 gwc388