Clin Oral Investig:肾脏疾病患者的口腔健康调查:一项从透析到肾移植的纵向研究

2017-05-02 lishiting MedSci原创

这篇研究的目的是为了比较患慢性肾脏疾病的患者透析(基线)和肾移植(进一步治疗)治疗阶段的口腔健康情况变化,并评估糖尿病肾病和其他肾脏疾病在追踪随访过程中的口腔健康差异。

这篇研究的目的是为了比较患慢性肾脏疾病的患者透析(基线)和肾移植(进一步治疗)治疗阶段的口腔健康情况变化,并评估糖尿病肾病和其他肾脏疾病在追踪随访过程中的口腔健康差异。

研究对53名年龄在31-86岁之间的肾脏疾病患者(男性34人)进行长达157个月的随访调查。受试者于芬兰Helsinki大学附属医院在透析治疗期间以及进一步的治疗阶段分别进行临床和放射线口腔检查、唾液和实验室分析以及口腔健康行为调查问卷,并记录检查结果。口腔炎症负荷程度通过测量深牙周袋、牙周炎症负荷(PIBI)、龋失补牙(DMFT)和总牙指数(TDI)进行评估。结果通过cross-tabulation Pearson chi-square或Fisher's exact test、Mann-Whitney U test和McNemar and Wilcoxon signed-rank test进行统计学分析。

结果显示,在透析阶段,更多的肾病患者检查出牙石和深牙周袋;并且,TDI、PIBI、牙齿数和唾液流速要明显高于随后的治疗阶段。另外,在随访调查过程中,与其他肾脏疾病相比,更多的糖尿病肾病患者检查出念珠菌以及更多的牙菌斑形成,并且使用更多的药物,而唾液流速却较低。

结论:肾病患者在进一步治疗阶段的口腔健康情况要好于透析阶段。但是,在这一阶段需要使用更多的药物进行治疗,并且口腔唾液流速也会明显降低,这一点需要注意!这篇研究表明,肾病患者在透析阶段治疗口腔感染灶是十分必要的,以此可以有效防止在肾移植后口腔疾病的加重。

原始出处

Nylund KM, Meurman JH, et al. Oral health in patients with renal disease: a longitudinal study from predialysis to kidney transplantation. Clin Oral Investig. 2017 Apr 20. doi: 10.1007/s00784-017-2118-y.

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    2017-06-11 小几洁
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    2017-05-11 cuiyejia

    学习了,谢谢

    0

  6. 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    2017-05-06 1e14ec7dm65(暂无匿称)

    肾病病情越重口腔感染可能性大,因此治疗肾病同时加强口腔感染治疗

    0

  7. 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ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=193175, encodeId=253c1931e5be, content=学习了很有用, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib3IzoRn621JdKCFUI4XvNELcibocrAVU6aUzEVDSaf3rYH08PUYUiagGqxAEhj8g9WqqNvD1CupIpCrmnR2OrqHZh/0, createdBy=7f181365728, createdName=飛歌, createdTime=Wed May 03 08:23:26 CST 2017, time=2017-05-03, status=1, ipAttribution=)]
    2017-05-04 1ddf0692m34(暂无匿称)

    口腔健康全身健康

    0

  8. 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content=学习了很有用, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib3IzoRn621JdKCFUI4XvNELcibocrAVU6aUzEVDSaf3rYH08PUYUiagGqxAEhj8g9WqqNvD1CupIpCrmnR2OrqHZh/0, createdBy=7f181365728, createdName=飛歌, createdTime=Thu May 04 02:16:14 CST 2017, time=2017-05-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=193327, encodeId=6e4819332e9c, content=学习一下谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzaiabIFicf63hKvVMjL6aJlx4yX4UcXmzX9DyibCRcicq0QtCRWMaQKh8MYjE1D3EKUBopgiaGWYuqbeR/0, createdBy=0c2b1999806, createdName=三生有幸9135, createdTime=Wed May 03 17:06:16 CST 2017, time=2017-05-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=193175, encodeId=253c1931e5be, content=学习了很有用, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib3IzoRn621JdKCFUI4XvNELcibocrAVU6aUzEVDSaf3rYH08PUYUiagGqxAEhj8g9WqqNvD1CupIpCrmnR2OrqHZh/0, createdBy=7f181365728, createdName=飛歌, createdTime=Wed May 03 08:23:26 CST 2017, time=2017-05-03, status=1, ipAttribution=)]
    2017-05-04 飛歌

    学习了很有用

    0

  9. 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ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=193175, encodeId=253c1931e5be, content=学习了很有用, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib3IzoRn621JdKCFUI4XvNELcibocrAVU6aUzEVDSaf3rYH08PUYUiagGqxAEhj8g9WqqNvD1CupIpCrmnR2OrqHZh/0, createdBy=7f181365728, createdName=飛歌, createdTime=Wed May 03 08:23:26 CST 2017, time=2017-05-03, status=1, ipAttribution=)]
    2017-05-03 三生有幸9135

    学习一下谢谢分享

    0

  10. 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    2017-05-03 飛歌

    学习了很有用

    0

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