Int J Oral Max Surg:口腔癌中与癌症相关的高钙血症

2018-04-22 MedSci MedSci原创

癌症相关性高钙血症(CRH)是晚期癌症患者中的重要副肿瘤疾病。在临床实践中,CRH患者的预后较差。

癌症相关性高钙血症(CRH)是晚期癌症患者中的重要副肿瘤疾病。在临床实践中,CRH患者的预后较差。

回顾了2003年1月1日至2015年12月31日在台中退伍军人综合医院诊断的3198例口腔癌CRH患者的病历资料。患者入选标准是诊断高钙血症或使用抗高钙血症药物。符合以下任何标准的患者被排除在外:使用全胃肠外营养,血清钙数据不完整,死亡日期未知。 CRH总发生率为6.95‰/年。共有91名患者入选;他们的中位生存时间是28天。患者按生存时间分为两组,以30天为界。在单变量分析中,血清白蛋白,白细胞增多症和氯膦酸盐使用降低对生存率具有统计学显着影响(所有P <0.05)。 45名患者(49.5%)复发CRH,其中9名在30天内死亡。这9例患者的首次CRH复发间隔时间(中位数为13天)要比存活≥30天(中位数为28天)的患者短(P <0.001)。据观察,首次发生CRH复发的短时间间隔是一个不良预后因素。

原始出处:

T.-C. Lin, et al. Cancer-related hypercalcemia in oral cancer. Internatonal Journal of Oral and Maxillofacial Surgery. 2018 June. doi:10.1016/j.ijom.2017.10.015

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    2018-10-03 小几洁
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    2018-05-07 沙漠浪人

    血钙与口腔癌

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=1953157, encodeId=934a195315e08, content=<a href='/topic/show?id=d441e1440e8' target=_blank style='color:#2F92EE;'>#癌症相关#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71440, encryptionId=d441e1440e8, topicName=癌症相关)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e9a6357, createdName=xiangyuzhou971, createdTime=Sun Sep 02 02:55:00 CST 2018, time=2018-09-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2020401, encodeId=c2d92020401c4, content=<a href='/topic/show?id=1584134451c' target=_blank style='color:#2F92EE;'>#Oral#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13445, encryptionId=1584134451c, topicName=Oral)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIpeueeYB1kem1yfEZrSYKBdZBoqac9USf0RxIgRICBIyDn4licyiaiakNnobeCDVpvwqaWgwTNeLRHA/132, createdBy=bb5e2500127, createdName=小几洁, createdTime=Wed Oct 03 00:55:00 CST 2018, time=2018-10-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=312885, encodeId=928c31288550, content=血钙与口腔癌, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTJUlbw1Mf1vppicGcaWPx1YUOgLgKccao77Rykbx3jiazqzwcyXMdzRIZkhFyBPqknibeuOGhXI1VzVg/0, createdBy=7f162154630, createdName=沙漠浪人, createdTime=Mon May 07 17:04:05 CST 2018, time=2018-05-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1569234, encodeId=50a9156923454, content=<a href='/topic/show?id=80b9102e78f6' target=_blank style='color:#2F92EE;'>#高钙血症#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102778, encryptionId=80b9102e78f6, topicName=高钙血症)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=432e15501492, createdName=marlenexl, createdTime=Tue Apr 24 08:55:00 CST 2018, time=2018-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=308522, encodeId=197e30852220, content=一起学习学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/TDiaAWyicHgedzX3wKo3qcxudVJib7AfibfvNeufHRF2jG3Bw8MmZyWjIhtBV1mpJI7Sy9n7RcBKK5t3CuOKuOFxkg/0, createdBy=dd702206933, createdName=wzb521zf, createdTime=Mon Apr 23 12:12:56 CST 2018, time=2018-04-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=308326, encodeId=6a7b308326f1, content=癌症相关性高钙血症(CRH)是晚期癌症患者中的重要副肿瘤疾病.在临床实践中.CRH患者的预后较差., beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7cJ6ejWUr2nIia8qOvAKNdLHr32Df6G8iaoaOx6pHaoiacwp26DaslxZHCGbibZhhCGven4rvmWP60GahtzgFjgCjR/0, createdBy=6b111703011, createdName=有备才能无患, createdTime=Sun Apr 22 23:02:22 CST 2018, time=2018-04-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=308300, encodeId=497a30830070, content=了解一下.谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/12/23/2f51002e1349ccda5be11c1eea1e1e60.jpg, createdBy=a22097948, createdName=天地飞扬, createdTime=Sun Apr 22 21:17:58 CST 2018, time=2018-04-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=308283, encodeId=9615308283a9, content=学习了.谢谢分享., beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/xkvRjYnJzzRJ2R0y7VhicibvkjPWHjIMmu4ZpKnE9cWAu4lVicS3uDUCfF4M4JWvrkrYfpb2KehPV0Ee29tPqyPEebBUibiaKhnvD/0, createdBy=f8412001184, createdName=惠映实验室, createdTime=Sun Apr 22 19:32:40 CST 2018, time=2018-04-22, status=1, ipAttribution=)]
  5. [GetPortalCommentsPageByObjectIdResponse(id=1953157, encodeId=934a195315e08, content=<a href='/topic/show?id=d441e1440e8' target=_blank style='color:#2F92EE;'>#癌症相关#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71440, encryptionId=d441e1440e8, topicName=癌症相关)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e9a6357, createdName=xiangyuzhou971, createdTime=Sun Sep 02 02:55:00 CST 2018, time=2018-09-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2020401, encodeId=c2d92020401c4, content=<a href='/topic/show?id=1584134451c' target=_blank style='color:#2F92EE;'>#Oral#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13445, encryptionId=1584134451c, topicName=Oral)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIpeueeYB1kem1yfEZrSYKBdZBoqac9USf0RxIgRICBIyDn4licyiaiakNnobeCDVpvwqaWgwTNeLRHA/132, createdBy=bb5e2500127, createdName=小几洁, createdTime=Wed Oct 03 00:55:00 CST 2018, time=2018-10-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=312885, encodeId=928c31288550, content=血钙与口腔癌, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTJUlbw1Mf1vppicGcaWPx1YUOgLgKccao77Rykbx3jiazqzwcyXMdzRIZkhFyBPqknibeuOGhXI1VzVg/0, createdBy=7f162154630, createdName=沙漠浪人, createdTime=Mon May 07 17:04:05 CST 2018, time=2018-05-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1569234, encodeId=50a9156923454, content=<a href='/topic/show?id=80b9102e78f6' target=_blank style='color:#2F92EE;'>#高钙血症#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102778, encryptionId=80b9102e78f6, topicName=高钙血症)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=432e15501492, createdName=marlenexl, createdTime=Tue Apr 24 08:55:00 CST 2018, time=2018-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=308522, encodeId=197e30852220, content=一起学习学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/TDiaAWyicHgedzX3wKo3qcxudVJib7AfibfvNeufHRF2jG3Bw8MmZyWjIhtBV1mpJI7Sy9n7RcBKK5t3CuOKuOFxkg/0, createdBy=dd702206933, createdName=wzb521zf, createdTime=Mon Apr 23 12:12:56 CST 2018, time=2018-04-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=308326, encodeId=6a7b308326f1, content=癌症相关性高钙血症(CRH)是晚期癌症患者中的重要副肿瘤疾病.在临床实践中.CRH患者的预后较差., beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7cJ6ejWUr2nIia8qOvAKNdLHr32Df6G8iaoaOx6pHaoiacwp26DaslxZHCGbibZhhCGven4rvmWP60GahtzgFjgCjR/0, createdBy=6b111703011, createdName=有备才能无患, createdTime=Sun Apr 22 23:02:22 CST 2018, time=2018-04-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=308300, encodeId=497a30830070, content=了解一下.谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/12/23/2f51002e1349ccda5be11c1eea1e1e60.jpg, createdBy=a22097948, createdName=天地飞扬, createdTime=Sun Apr 22 21:17:58 CST 2018, time=2018-04-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=308283, encodeId=9615308283a9, content=学习了.谢谢分享., beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/xkvRjYnJzzRJ2R0y7VhicibvkjPWHjIMmu4ZpKnE9cWAu4lVicS3uDUCfF4M4JWvrkrYfpb2KehPV0Ee29tPqyPEebBUibiaKhnvD/0, createdBy=f8412001184, createdName=惠映实验室, createdTime=Sun Apr 22 19:32:40 CST 2018, time=2018-04-22, status=1, ipAttribution=)]
    2018-04-23 wzb521zf

    一起学习学习

    0

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    2018-04-22 有备才能无患

    癌症相关性高钙血症(CRH)是晚期癌症患者中的重要副肿瘤疾病.在临床实践中.CRH患者的预后较差.

    0

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    2018-04-22 天地飞扬

    了解一下.谢谢分享!

    0

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    2018-04-22 惠映实验室

    学习了.谢谢分享.

    0

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