Diabetes Care:孕前习惯性摄入叶酸与妊娠期糖尿病风险

2019-04-23 xing.T 网络

由此可见,妊娠前习惯性补充较高叶酸摄入量与较低的GDM风险显著相关。如果得到证实,这些研究结果表明孕前补充叶酸可以提供一种新的低成本途径来降低GDM风险。

近日,糖尿病领域权威杂志Diabetes Care上发表了一篇研究文章,研究人员旨在通过检查孕前习惯性叶酸摄入量与GDM风险之间的关系,确定妊娠期糖尿病(GDM)的新型可改变危险因素。 

该研究纳入了护士健康研究II中的14553名女性,她们在1991年和2001年期间的问卷调查中报告了至少一次单胎妊娠。使用每4年一次的食物频率问卷评估了孕前总叶酸、补充叶酸和食物叶酸的摄入量。GDM由自我报告的医生诊断确定。研究人员使用对数二项式模型估计GDM的相对风险(RR),并调整人口统计学指标、生活方式和饮食因素。 

在研究随访中,该研究共20199次妊娠中报告了824次GDM事件。叶酸摄入量足够(≥400μg/天)的女性与摄入不足(<400μg/天)的女性相比,GDM的RR为0.83(95%CI为0.72-0.95,P=0.007)。这种关联完全由补充叶酸摄入量所驱动。与没有补充叶酸摄入量相比,补充叶酸摄入量为1-399、400-599和≥600μg/天GDM的RR分别为0.83、0.77和0.70(趋势P=0.002)。在进一步调整摄入多种维生素和其他微量营养素以及可能计划怀孕的女性后,补充叶酸摄入量与GDM风险之间的关联仍然存在。 

由此可见,妊娠前习惯性补充较高叶酸摄入量与较低的GDM风险显著相关。如果得到证实,这些研究结果表明孕前补充叶酸可以提供一种新的低成本途径来降低GDM风险。 

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    2019-07-01 szhvet
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    2019-05-06 xiaodengzi

    哪里有全文可下

    0

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    2019-04-25 wjcjjian
  7. [GetPortalCommentsPageByObjectIdResponse(id=1639083, encodeId=2fc21639083df, content=<a href='/topic/show?id=afda591646' target=_blank style='color:#2F92EE;'>#DIA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5916, encryptionId=afda591646, topicName=DIA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=987022654425, createdName=ms9608593228839890, createdTime=Fri Jul 05 07:05:00 CST 2019, time=2019-07-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1761092, encodeId=927c1e6109236, content=<a href='/topic/show?id=9bea33520d' target=_blank style='color:#2F92EE;'>#BET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3352, encryptionId=9bea33520d, topicName=BET)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9a1a37427546, createdName=ms5439512287675881, createdTime=Thu Oct 31 10:05:00 CST 2019, time=2019-10-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1659595, encodeId=428916595953e, content=<a href='/topic/show?id=c42845239ef' target=_blank style='color:#2F92EE;'>#孕前#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=45239, encryptionId=c42845239ef, topicName=孕前)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=2c8925003801, createdName=szhvet, createdTime=Mon Jul 01 12:05:00 CST 2019, time=2019-07-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1902241, encodeId=d3241902241fc, content=<a href='/topic/show?id=c097591ed5' target=_blank style='color:#2F92EE;'>#Diabetes#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5917, encryptionId=c097591ed5, topicName=Diabetes)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0045169, createdName=木头人513, createdTime=Tue Mar 03 17:05:00 CST 2020, time=2020-03-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=365841, encodeId=1cf2365841f5, content=哪里有全文可下, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/4sPiciau2eSo8iabklbS8UVgdFvPV0gZbUpeZ7I1KV1dxAxPaRVJCEyHobI3b1GJeJbAnGgc4hibnpnmxRcY7XdmYw/132, createdBy=bdcc2425097, createdName=xiaodengzi, createdTime=Mon May 06 21:33:21 CST 2019, time=2019-05-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1251201, encodeId=9185125120135, content=<a href='/topic/show?id=90494486837' target=_blank style='color:#2F92EE;'>#妊娠期#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=44868, encryptionId=90494486837, topicName=妊娠期)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0b7c20, createdName=wjcjjian, createdTime=Thu Apr 25 00:05:00 CST 2019, time=2019-04-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1253644, encodeId=897912536445e, content=<a href='/topic/show?id=9d5d44888a9' target=_blank style='color:#2F92EE;'>#妊娠期糖尿病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=44888, encryptionId=9d5d44888a9, topicName=妊娠期糖尿病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a9de34, createdName=shenxlcyp, createdTime=Thu Apr 25 00:05:00 CST 2019, time=2019-04-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1042401, encodeId=ae4d1042401ff, content=谢谢MedSci提供最新的资讯, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=misszhang, createdTime=Tue Apr 23 12:05:00 CST 2019, time=2019-04-23, status=1, ipAttribution=)]
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    2019-04-23 misszhang

    谢谢MedSci提供最新的资讯

    0

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Nature Commun:女性孕前饮食或“终身影响婴儿DNA”

一项新的研究结果表明,妇女在受孕期间的饮食或将对其腹中的孩子的DNA产生持续的影响,甚至有可能是终身的。 在这项新的研究中,研究者对非洲西部冈比亚农村地区的妇女的饮食进行了调查,冈比亚是一个一年中只有雨季和旱季的国度,在每年其饮食也经历主要的变化。 “雨季常被认为是一个‘饥饿的季节’,而旱季则被认为是‘丰收的季节’,”来自休斯敦贝勒医学院的研究者营养表观遗传学家Robert Waterland说到

AJCN:孕前改善机体健康或可有效抑制后代肥胖

近日,一项刊登在国际杂志The American Journal of Clinical Nutrition上的研究论文中,来自南安普顿大学的研究人员通过研究发现,女性孕前改善机体健康或者可以帮助有效预防个体后代肥胖;文章中研究者为揭示儿童早期生长环境和后期患肥胖间的关系又提供了新的研究证据,此前研究者鉴别出了一系列风险因子,但却很少评估其对肥胖的联合效应。 这项研究中研究者发现了许多可以预

Lancet:警惕!受孕前父母的饮食会影响孩子健康

孩子的健康状况不仅会受到孕期吸烟或饮酒的母亲的影响,还与父母在生育前的肥胖和饮食不良有关。近日,研究人员在三份研究报告中警告说,怀孕前母亲和父亲的饮食,以及他们是否严重超重,都可能对他们孩子的成长、发育和长期健康产生深远的影响。

NEJM:甲状腺过氧化物酶抗体阳性女性在孕前服用左旋甲状腺素的效果如何?

由此可见,在甲状腺过氧化物酶抗体阳性的甲状腺功能正常女性中使用左旋甲状腺素不会得到比安慰剂更高的活产率。

Hypertension:美国研究称,孕前和孕早期血压升高与反复流产有关

美国国立卫生研究院尤妮斯甘乃迪施莱佛国家儿童健康与人类发展研究所发表的一项新的研究结果表明,孕前以及孕早期血压升高与反复流产有关。

控制孕期体重和促进母乳喂养可降低儿童肥胖

Kaiser Permanente的一项新研究发表在《Pediatric Obesity》上,文章显示怀孕前肥胖和孕期体重过度增加与儿童在2岁时超重的风险相关。研究还发现母乳喂养至少到婴儿六个月时才会降低孩子到2岁时超重的可能性。 根据美国疾病控制和预防中心称,在过去的30年里,肥胖儿童已增长逾一倍,青少年中超过四倍,而在2012年,已发现超过三分之一的儿童和青少年有超重或肥胖现象。 “