HBP:有较少适应性感觉处理和特质焦虑的母亲的小脑静息状态活动增加

2021-07-19 MedSci原创 MedSci原创

fALFF可能是一个有临床意义的指标,检测母亲特质焦虑作为一个因素的育儿压力。

特质焦虑水平高的育儿母亲倾向于较少的适应性感觉加工,从而导致育儿压力。然而,这种感觉加工和特质焦虑的神经机制尚不清楚。

Akemi Tomoda等为了确定全脑自发神经活动和感觉加工特点的母亲与不同的育儿压力水平进行了功能磁共振研究,研究结果发表在human brain mapping杂志。

利用静息态功能磁共振成像,该研究评估了照顾一个以上学龄前儿童(2-5岁)的母亲,她们表现出不同程度的感觉处理、特质焦虑和养育压力。采用基于fALFF的全脑相关分析来评估选定脑区域的自发神经活动。

(a)散点图显示了STAI的特质分数与AASP总分的关系。(b)显示PSI分数与AASP总分关系的散点图。

该研究发现感觉加工水平与特质焦虑和父母压力之间存在显著的正相关。感觉处理适应性较差的母亲显著增加了小脑左侧第六小叶的静息状态网络活动。

使用快速傅立叶变换测量fALFF的静息态网络活动显著增加的脑区。主要簇在左侧小脑、VI小叶;Talairach坐标x=-30,y=-60,z=-24;簇大小=80体素;Z=4.06。

STAI的特质得分与AASP总分之间的关系受左小脑、小叶静息态活动(fALFF值)的中介路径模型的影响。*, p <.05; **, p <.01; n.s., 无意义。

该研究发现揭示了使用AASP总分评估的感觉加工程度与左第六小叶静息状态大脑活动之间的关联。AASP总分较高的个体,其特质焦虑和父母压力水平较高,分别通过STAI和PSI得分进行评估。此外,通径分析显示左侧小脑第六小叶的fALFF值介导特质焦虑水平对AASP总分的影响。该研究阐明了这一区域参与母亲感觉加工的神经机制。

左侧第六小叶fALFF值的增加证实了特质焦虑与感觉加工之间的中介作用。第六小叶大脑活动增加导致的适应性感觉处理能力下降的趋势可能是母亲特质焦虑和父母压力风险的一个指标。

这项研究证明了育儿母亲左小脑第六小叶的fALFF值是影响不同水平特质焦虑和较低适应性感觉加工的神经功能标志。此外, fALFF可能是一个有临床意义的指标,检测母亲特质焦虑作为一个因素的育儿压力。确定每日感觉刺激的这一指标可用于筛选有虐待儿童风险的父母,以便进行早期指导干预,并进一步阐明不同水平的特质焦虑和养育压力的个体差异。将来有可能建立针对具有各种感官处理模式的个体的治疗(心理教育),这将充分缓解父母的压力和焦虑。综上所述,这些方法,包括早期筛查和心理教育,对于帮助母亲应对养育期间感觉加工适应性较差的趋势,并与孩子形成稳定的依恋关系至关重要,这有助于防止虐待儿童。

原文出处

Increased resting-state activity in the cerebellum with mothers having less adaptive sensory processing and trait anxiety.  https://doi.org/10.1002/hbm.25594

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  3. [GetPortalCommentsPageByObjectIdResponse(id=2078420, encodeId=3e4220e842068, content=<a href='/topic/show?id=3b04990841c' target=_blank style='color:#2F92EE;'>#静息状态#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99084, encryptionId=3b04990841c, topicName=静息状态)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=08e964, createdName=drwjr, createdTime=Mon May 09 00:33:43 CST 2022, time=2022-05-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1621048, encodeId=b1b2162104863, content=<a href='/topic/show?id=dccc94e01c9' target=_blank style='color:#2F92EE;'>#适应性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=94701, encryptionId=dccc94e01c9, topicName=适应性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=智慧医人, createdTime=Wed Jul 21 02:33:43 CST 2021, time=2021-07-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1000970, encodeId=bc7410009e046, content=对临床有指导, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2018/08/20/54886e9842d0997b08ed3f134c538d9d.jpg, createdBy=0d1e1365885, createdName=yesaisai133, createdTime=Mon Jul 19 22:51:53 CST 2021, time=2021-07-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1050570, encodeId=03b610505e024, content=焦虑是当年年轻人的共同问题,需要认真对待。, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=明天jing, createdTime=Mon Jul 19 14:33:43 CST 2021, time=2021-07-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1000842, encodeId=a17810008429a, content=已读已读已读已读已读,学习学习学习学习学习,受益匪浅, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f03a5433387, createdName=ms5000000518166734, createdTime=Mon Jul 19 11:39:43 CST 2021, time=2021-07-19, status=1, ipAttribution=)]
    2021-07-19 yesaisai133

    对临床有指导

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=2078420, encodeId=3e4220e842068, content=<a href='/topic/show?id=3b04990841c' target=_blank style='color:#2F92EE;'>#静息状态#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99084, encryptionId=3b04990841c, topicName=静息状态)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=08e964, createdName=drwjr, createdTime=Mon May 09 00:33:43 CST 2022, time=2022-05-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1621048, encodeId=b1b2162104863, content=<a href='/topic/show?id=dccc94e01c9' target=_blank style='color:#2F92EE;'>#适应性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=94701, encryptionId=dccc94e01c9, topicName=适应性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=智慧医人, createdTime=Wed Jul 21 02:33:43 CST 2021, time=2021-07-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1000970, encodeId=bc7410009e046, content=对临床有指导, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2018/08/20/54886e9842d0997b08ed3f134c538d9d.jpg, createdBy=0d1e1365885, createdName=yesaisai133, createdTime=Mon Jul 19 22:51:53 CST 2021, time=2021-07-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1050570, encodeId=03b610505e024, content=焦虑是当年年轻人的共同问题,需要认真对待。, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=明天jing, createdTime=Mon Jul 19 14:33:43 CST 2021, time=2021-07-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1000842, encodeId=a17810008429a, content=已读已读已读已读已读,学习学习学习学习学习,受益匪浅, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f03a5433387, createdName=ms5000000518166734, createdTime=Mon Jul 19 11:39:43 CST 2021, time=2021-07-19, status=1, ipAttribution=)]
    2021-07-19 明天jing

    焦虑是当年年轻人的共同问题,需要认真对待。

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=2078420, encodeId=3e4220e842068, content=<a href='/topic/show?id=3b04990841c' target=_blank style='color:#2F92EE;'>#静息状态#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99084, encryptionId=3b04990841c, topicName=静息状态)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=08e964, createdName=drwjr, createdTime=Mon May 09 00:33:43 CST 2022, time=2022-05-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1621048, encodeId=b1b2162104863, content=<a href='/topic/show?id=dccc94e01c9' target=_blank style='color:#2F92EE;'>#适应性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=94701, encryptionId=dccc94e01c9, topicName=适应性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=智慧医人, createdTime=Wed Jul 21 02:33:43 CST 2021, time=2021-07-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1000970, encodeId=bc7410009e046, content=对临床有指导, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2018/08/20/54886e9842d0997b08ed3f134c538d9d.jpg, createdBy=0d1e1365885, createdName=yesaisai133, createdTime=Mon Jul 19 22:51:53 CST 2021, time=2021-07-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1050570, encodeId=03b610505e024, content=焦虑是当年年轻人的共同问题,需要认真对待。, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=明天jing, createdTime=Mon Jul 19 14:33:43 CST 2021, time=2021-07-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1000842, encodeId=a17810008429a, content=已读已读已读已读已读,学习学习学习学习学习,受益匪浅, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f03a5433387, createdName=ms5000000518166734, createdTime=Mon Jul 19 11:39:43 CST 2021, time=2021-07-19, status=1, ipAttribution=)]
    2021-07-19 ms5000000518166734

    已读已读已读已读已读,学习学习学习学习学习,受益匪浅

    0

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