Am J Gastroenterol:IBD患者,需注意维生素D水平

2016-03-23 MedSci MedSci原创

研究者进行了一项研究,探究维生素D水平和炎症性肠病(IBD)的关系。研究者对IBD患者进行了长达5年的随访,根据患者的维生素D水平将其分类。通过使用药物类型、医疗利用率、炎症相关生化标志物(CRP和ESR)、疼痛、临床疾病活动评分和健康相关生活质量评估患者IBD的临床状况。研究数据显示,纳入的965名IBD患者中,克罗恩病占61.9%,溃疡性结肠炎占38.1%,患者平均年龄44岁,其中女性占52.

研究者进行了一项研究,探究维生素D水平和炎症性肠病(IBD)的关系。

研究者对IBD患者进行了长达5年的随访,根据患者的维生素D水平将其分类。通过使用药物类型、医疗利用率、炎症相关生化标志物(CRP和ESR)、疼痛、临床疾病活动评分和健康相关生活质量评估患者IBD的临床状况。

研究数据显示,纳入的965名IBD患者中,克罗恩病占61.9%,溃疡性结肠炎占38.1%,患者平均年龄44岁,其中女性占52.3%。所有患者中,29.9%的患者维生素D水平低。5年的随访时间里,与维生素D水平正常的患者相比,低水平的维生素D组需要更多的类固醇激素、生物制剂、麻醉、CT扫描、急救科就诊、住院和手术 (P<0.05)。

不仅如此,低水平维生素D组患者的疼痛、临床疾病活动评分和健康相关生活质量更糟糕(P<0.05)。使用维生素D补充剂的患者可显著减少他们的医疗利用率。

研究结果表明,IBD患者中常见低水平的维生素D,而该种维生素的缺乏又于发病率和严重程度相关,因此其潜在影响,临床上要对维生素D进行监测并治疗。

原始出处:


Kabbani TA,Koutroubakis IE,Schoen RE,et al.Association of Vitamin D Level With Clinical Status in Inflammatory Bowel Disease: A 5-Year Longitudinal Study.Am J Gastroenterol 2016 Mar 8;


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    2017-02-08 许安
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    2016-03-25 bnurmamat

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