BMC Anesthesiology:羟乙基淀粉不能改善术后患者恶心症状

2013-07-11 无奈的风铃 dxy

国际麻醉指南建议静脉补液可以改善患者术后恶心、呕吐的症状。但尚无统一的治疗方案,针对这一问题,来自爱尔兰都柏林Rotunda医院的Conan McCaul等人进行了一项前沿性研究,该研究对比分析了等体积胶体液(羟乙基淀粉 130/0.4)和晶体液(Hartmann氏溶液)对妇产科腹腔镜术后患者恶心、呕吐症状的改善。该研究结果发表在2012年7月31日的BMC麻醉学杂志上(BMC Anesthesi

国际麻醉指南建议静脉补液可以改善患者术后恶心、呕吐的症状。但尚无统一的治疗方案,针对这一问题,来自爱尔兰都柏林Rotunda医院的Conan McCaul等人进行了一项前沿性研究,该研究对比分析了等体积胶体液(羟乙基淀粉 130/0.4)和晶体液(Hartmann氏溶液)对妇产科腹腔镜术后患者恶心、呕吐症状的改善。该研究结果发表在2012年7月31日的BMC麻醉学杂志上(BMC Anesthesiology)。

该研究全组共120例,随机分为胶体组60例,晶体组60例。术中补液速度每小时为1.5ml/kg。变量包括恶心、呕吐、止吐药物的使用、头晕、咽喉痛、头痛、一般感觉。术后30min、2h、24h、48h分别记录上述变量。部分患者给予肺功能测试。术后2h患者出现恶心症状两组对比胶体组38.2%、晶体组17.9%,P=0.03。而恶心评估表得分胶体组为1.49±0.3(平均值±标准差),晶体组为0.68 ± 0.2,P=0.028。两组呕吐的发生率均较低无明显差异。在咽喉痛、头晕、头痛、一般感觉这些变量方面,两组也无明显差异。部分患者术后出现FVC、FEV-1和PEFR降低,但两组无明显差异。
该研究组发现相对于晶体溶液来说,使用胶体溶液可增加妇产科腹腔镜手术术后患者早期出现恶心症状的风险。


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    2015-12-26 hixiaoluo

    值得收藏,学习,谢谢分享

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    2013-07-13 skhzy

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