Int J Impot Res:地中海饮食和前列腺癌风险研究

2018-10-28 AlexYang MedSci原创

前列腺癌(PCa)是第二最常见诊断的癌症,并且是世界范围内引起死亡排名第6的疾病。与其他欧洲国家相比,那些遵从地中海饮食习惯的国家被报道具有更低的PCa发生率和死亡率。最近,有研究人员在2015年1月到2016年12月之间进行了一个基于群体的案例-对照研究,地点在意大利南部卡塔尼亚的一个单独的机构。研究总共包括了118名PCa患者和238名基于群体的对照。对照具有对地中海饮食更高的依从性,并且在一

前列腺癌(PCa)是第二最常见诊断的癌症,并且是世界范围内引起死亡排名第6的疾病。与其他欧洲国家相比,那些遵从地中海饮食习惯的国家被报道具有更低的PCa发生率和死亡率。

最近,有研究人员在2015年1月到2016年12月之间进行了一个基于群体的案例-对照研究,地点在意大利南部卡塔尼亚的一个单独的机构。研究总共包括了118名PCa患者和238名基于群体的对照。对照具有对地中海饮食更高的依从性,并且在一些亚群中非常明显(包括年龄组,超重的肥胖男性,抽烟,饮酒和低程度和中等程度体育锻炼水平)。研究发现,与对照相比,PCa案例消耗更少的蔬菜(223g/d vs. 261g/d; p=0.001),豆类(34.26g/d vs. 53.55g/d; p=0.003),鱼类(47.75g/d vs. 58.3g/d);其他差异表现在酒精摄入(12.37g/d vs 5.07g/d; p<0.01),谷类食品(254.06g/d vs.235.94g/d; p<0.001),奶制品(196g/d vs. 166g/d; p<0.001)和肉类(98.09g/d vs. 70.15g/d; p<0.001)。然而,在案例和对照组之间,研究人员并没有发现在水果,豆类和橄榄油消费方面的差异。另外,地中海饮食评分与患有PCa具有线性负相关关系(风险比 [OR]: 0.86 [95% CI 0.77-0.96])。特别的是,具有最高地中海饮食依从性的个体患前列腺癌的风险降低78%,且评分每增加一点可能性减少14%。另外,多酚摄入量模型表明地中海饮食依从性和PCa之间具有负相关关系,并且更加线性化,且在评分每增加1点中并不显著(OR: 0.88 [95% CI 0.77-1.01])。

最后,研究人员指出,他们的研究表明了地中海饮食的高依从性与患有PCa可能性表现为负相关关系。

原始出处:

Giorgio Ivan Russo, Tatiana Solinas, Daniele Urzì et al. Adherence to Mediterranean diet and prostate cancer risk in Sicily: population-based case-control study. Int J Impot Res. 18 Oct 2018.

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    2019-09-30 sjq027
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    2018-10-31 健康达人

    地中海饮食是热点,被认为是最健康的饮食,而中国传统饮食一般被认为多半是不健康的,这是事实吗?其实需要更多严谨的科学证据,而不是猜测!

    0

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    2018-10-30 风铃826
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    2018-10-30 wgx311

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