Anesth Analg:疑似伴病理性胎盘附着的前置胎盘剖宫产术的椎管内麻醉:回顾性分析

2018-04-01 王子君 “罂粟花”微信号

由于出血和子宫切除的风险增加,对于疑似伴病理性胎盘附着(MAP)前置胎盘的患者,通常选择全麻(GA)进行剖宫产术(CD)。我们回顾分析了椎管内麻醉(NA)下行剖宫产术的产妇结局和转为GA的风险率。

背景与目的:由于出血和子宫切除的风险增加,对于疑似伴病理性胎盘附着(MAP)前置胎盘的患者,通常选择全麻(GA)进行剖宫产术(CD)。我们回顾分析了椎管内麻醉(NA)下行剖宫产术的产妇结局和转为GA的风险率。

方  法:我们对从1997年到2015年疑似伴MAP前置胎盘接受非急诊CD的产妇进行一项单中心、回顾性队列研究。根据患者是否接受GA、NA或术中从NA转为GA,对患者进行分类。主要观察指标为术后敏锐度,定义为需要进入重症监护病房,动脉栓塞,再次手术或持续输注≥3单位的红细胞。我们另外确定变量与子宫切除术中从NA转为GA的概率呈正相关。用逻辑回归模型来控制混杂。

结  果:在疑似伴MAP的前置胎盘患者中,接受非急诊CD的129名患者中,122名(95%)接受NA为主要麻醉方式。大多数患者的体重指数≥40kg / m(9/10,90%),既往CD≥3(18/20,90%),怀疑胎盘增大或过度(2935,83%),Mallampati分级≥3(19中21,90%)。72例NA患者术中需要切除子宫,15例(21%)术中需要转换为GA。转换为GA的患者输注大量红细胞的比率较高(60%vs 25%; P = 0.01),输血量相似(9%比7%; P = 1.0)。此外,患者术后敏锐度的发生率也较高(47%vs 4%; P <.0001),其中包括5例在大容量复苏后需在重症监护室给予呼吸支持管理。校正多个混杂因素后,子宫切除术患者需转为GA的唯一独立预测因子是更长的手术时间(校正比值比1.54,95%CI 1.01.2.42)和≥3次的CD史(校正比值比6.45,95%CI,1.12.45.03)。

结  论:NA可成功用于大多数疑似伴MAP的前置胎盘患者。我们的研究结果支持这类患者在子宫切除术期间可选择性转为GA,重点关注手术较复杂的患者。

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    2019-01-06 经常头晕
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    2018-05-01 bugit
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  4. [GetPortalCommentsPageByObjectIdResponse(id=1700068, encodeId=66901e00068a0, content=<a href='/topic/show?id=295524e541' target=_blank style='color:#2F92EE;'>#Anal#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2475, encryptionId=295524e541, topicName=Anal)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=de3a29999500, createdName=经常头晕, createdTime=Sun Jan 06 02:55:00 CST 2019, time=2019-01-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1690764, encodeId=58641690e64c3, content=<a href='/topic/show?id=de3362880f1' target=_blank style='color:#2F92EE;'>#椎管内#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62880, encryptionId=de3362880f1, topicName=椎管内)], attachment=null, authenticateStatus=null, createdAvatar=null, 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topicList=[TopicDto(id=2471, encryptionId=377824e1c0, topicName=ANA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=434d22047430, createdName=AspirantSuo, createdTime=Fri May 11 09:55:00 CST 2018, time=2018-05-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1953105, encodeId=ae211953105b4, content=<a href='/topic/show?id=3b7962884e0' target=_blank style='color:#2F92EE;'>#椎管内麻醉#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62884, encryptionId=3b7962884e0, topicName=椎管内麻醉)], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=47c5349, createdName=tastas, createdTime=Mon Sep 24 23:55:00 CST 2018, time=2018-09-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2051108, encodeId=5d3f2051108a0, content=<a href='/topic/show?id=95f8e042dd' target=_blank style='color:#2F92EE;'>#EST#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7042, encryptionId=95f8e042dd, topicName=EST)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e9a6357, createdName=xiangyuzhou971, createdTime=Fri Mar 01 21:55:00 CST 2019, time=2019-03-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1799695, encodeId=e9fd1e996956c, content=<a href='/topic/show?id=f850e1037bd' target=_blank style='color:#2F92EE;'>#病理性胎盘附着#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71037, encryptionId=f850e1037bd, topicName=病理性胎盘附着)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=03e7496, createdName=楚钟, createdTime=Sun Dec 23 10:55:00 CST 2018, time=2018-12-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1395246, encodeId=3112139524632, content=<a href='/topic/show?id=c0e43265992' target=_blank style='color:#2F92EE;'>#前置胎盘#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=32659, encryptionId=c0e43265992, topicName=前置胎盘)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=24a22500182, createdName=1696533704_45270454, createdTime=Tue Apr 03 03:55:00 CST 2018, time=2018-04-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1406846, encodeId=0e94140684602, content=<a href='/topic/show?id=2aca8365e2c' target=_blank style='color:#2F92EE;'>#胎盘#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83657, encryptionId=2aca8365e2c, topicName=胎盘)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTItxfbnwF4Yku2j227me6wl2EGarBoTicR3tHxrMtib5tnyyEEsgxlHkk8JAS4ZjHsEF7PxhBwh1QwQ/132, createdBy=c8162575557, createdName=liuyong2981, createdTime=Tue Apr 03 03:55:00 CST 2018, time=2018-04-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1516772, encodeId=2cb71516e724d, content=<a href='/topic/show?id=67e940555fb' target=_blank style='color:#2F92EE;'>#回顾性分析#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=40555, encryptionId=67e940555fb, topicName=回顾性分析)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=7d6111012350, createdName=小小小向日葵, createdTime=Tue Apr 03 03:55:00 CST 2018, time=2018-04-03, status=1, ipAttribution=)]
    2018-05-11 AspirantSuo
  5. 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  6. 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style='color:#2F92EE;'>#EST#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7042, encryptionId=95f8e042dd, topicName=EST)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e9a6357, createdName=xiangyuzhou971, createdTime=Fri Mar 01 21:55:00 CST 2019, time=2019-03-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1799695, encodeId=e9fd1e996956c, content=<a href='/topic/show?id=f850e1037bd' target=_blank style='color:#2F92EE;'>#病理性胎盘附着#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71037, encryptionId=f850e1037bd, topicName=病理性胎盘附着)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=03e7496, createdName=楚钟, createdTime=Sun Dec 23 10:55:00 CST 2018, time=2018-12-23, status=1, ipAttribution=), 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  7. 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createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTItxfbnwF4Yku2j227me6wl2EGarBoTicR3tHxrMtib5tnyyEEsgxlHkk8JAS4ZjHsEF7PxhBwh1QwQ/132, createdBy=c8162575557, createdName=liuyong2981, createdTime=Tue Apr 03 03:55:00 CST 2018, time=2018-04-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1516772, encodeId=2cb71516e724d, content=<a href='/topic/show?id=67e940555fb' target=_blank style='color:#2F92EE;'>#回顾性分析#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=40555, encryptionId=67e940555fb, topicName=回顾性分析)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=7d6111012350, createdName=小小小向日葵, createdTime=Tue Apr 03 03:55:00 CST 2018, time=2018-04-03, status=1, ipAttribution=)]