Hypertension:每日步数与动脉僵硬度

2018-12-21 xing.T MedSci原创

由此可见,该系统评价和荟萃分析显示,每天客观监测的步骤与PWV之间存在临床意义的关联,PWV是动脉僵硬度的公认指标,也是心血管疾病的早期亚临床危险因素。

动脉僵硬度已成为血管发病率和死亡率的独立预测因子。此外,人们普遍认为,每天客观监测的步数有利于控制健康风险因素,并有助于预防发病率和死亡率。近日,血管权威杂志Hypertension上发表了一篇研究文章,该评价的目的是确定每日步数与通过脉搏波速度(PWv)来测量的动脉僵硬度之间的关系。

研究人员系统地检索了解决每日步数与PWv之间关联研究的横断面数据。DerSimonian和Laird方法用于计算相关的汇总估计值及其各自的95%CI。此外,研究人员使用回归模型估计了根据身体活动分组的合并平均PWv:久坐<5000;低活动程度5000至7499;活跃7500至9999;高度活跃为10000+。

该系统评价纳入了20项已发表的研究,但只有10项成人和老年人研究可纳入荟萃分析。每天步数与成人和老年人经PWV测量的动脉僵硬度呈负相关(r=-0.18; 95%CI为-0.27至-0.10; P<0.001),具有显著的异质性(I2=77.9%; P<0.001)。回归模型显示,汇总的PWV较低,每天的步数水平相应较高,主要受高度活跃生活方式组受试者的低PWv值影响(趋势P=0.005)。

由此可见,该系统评价和荟萃分析显示,每天客观监测的步骤与PWV之间存在临床意义的关联,PWV是动脉僵硬度的公认指标,也是心血管疾病的早期亚临床危险因素。

原始出处:

Iván Cavero-Redondo,et al. Steps per Day and Arterial Stiffness Systematic Review and Meta-Analysis
Hypertension.2018.https://www.ahajournals.org/doi/10.1161/HYPERTENSIONAHA.118.11987

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    2019-09-08 feather89
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    2018-12-23 jyzxjiangqin

    每日步数与动脉僵硬度。

    0

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