JACC:外周动脉疾病患者预后的存在性别差异

2020-02-22 不详 MedSci原创

外周动脉疾病(PAD)会增加主要不良心血管事件(MACE)的风险。本研究的目的旨在评估PAD患者的MACE风险的性别差异。本EUCLID临床研究纳入分析了13885名PAD患者(女性占28%),不同性别患者之间的PAD严重程度和药物治疗无明显差异。女性患者的年龄更大(p < 0.001),且糖尿病、高血压高脂血症和慢性肾脏疾病的概率更大。经过平均30个月时间的随访,女性患者的MACE风险更低

外周动脉疾病(PAD)会增加主要不良心血管事件(MACE)的风险。本研究的目的旨在评估PAD患者的MACE风险的性别差异。

本EUCLID临床研究纳入分析了13885名PAD患者(女性占28%),不同性别患者之间的PAD严重程度和药物治疗无明显差异。女性患者的年龄更大(p < 0.001),且糖尿病高血压高脂血症和慢性肾脏疾病的概率更大。经过平均30个月时间的随访,女性患者的MACE风险更低(9.5% vs. 11.2%;p < 0.001),全因死亡率更低(7.6% vs. 9.7%; p < 0.001)。另外,主要不良肢体事件无明显性别差异。

研究结果显示,对于外周动脉疾病患者,女性的主要不良心血管事件风险更低,而主要不良肢体事件风险无明显差异。

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    2020-12-02 hbwxf
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