Dent Mater J:酸诱导BioUnionTM释放锌离子以及其对变形链球菌的抑制作用分析

2020-03-20 lishiting MedSci原创

BioUnionTM填料嫩巩固在酸环境下释放Zn2+。这篇研究的目的是为了评估BioUnionTM填料在酸条件下离子释放的模式以及它对变形链球菌的抗菌效果。

整合入修复/涂层材料中的BioUnionTM填料是一种全新的生物活性玻璃粉末。BioUnionTM填料最特别的功能是在酸环境下能够释放Zn2+。这篇研究的目的是为了评估BioUnionTM填料在酸条件下离子释放的模式以及它对变形链球菌的抗菌效果。

结果显示,BioUnion填料在乙酸中释放Zn2+的浓度要明显高于其在水中释放的浓度。BioUnion填料在有蔗糖的情况下对变形链球菌的抑制作用显著高于无蔗糖条件,表明添加蔗糖后悬浮状态的pH水平降低。酸暴露能够增加BioUnion填料的Zn2+释放,并且填料反复暴露于酸环境展示出对变形链球菌明显的抑制作用。

结论:这些结果表明,BioUnion填料在酸环境下能够加速Zn2+的释放,进而诱导对变脸链球菌的杀菌/抑制作用。

原始出处

Liu Y, Kohno T, et al. Acidity-induced release of zinc ion from BioUnionTM filler and its inhibitory effects against Streptococcus mutans. Dent Mater J. 2020 Feb 21. doi: 10.4012/dmj.2019-061.

 

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    2020-07-15 sunylz
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