Thorax：孕期和婴儿期接触细颗粒物对小儿过敏性鼻炎的影响

2021-03-16 AlexYang MedSci原创

产前和产后接触细颗粒物(PM2.5)对过敏性鼻炎(AR)发展的影响尚不清楚。

产前和产后接触细颗粒物(PM2.5)对过敏性鼻炎(AR)发展的影响尚不清楚。

最近，有研究人员进一步确定了AR发展的易发期，以确定降低不良影响的方法。

研究包括了140911名单胎活婴的大型人群出生队列，评估了产前和产后早期暴露对AR发病的影响。结果表明，在140911名儿童中，有47276名(33.55%)为AR病例。AR患儿初诊时的平均年龄为2.97±1.78岁。研究人员发现AR与妊娠30周至出生后52周PM2.5的四分位数范围（IQR 17.98 ？g/m3）的增加有显著相关性。暴露-反应关系表明，AR与PM2.5的26-76 ？g/m3之间有显著的正相关关系（调整后OR 1.00至1.05）。

最后，研究人员指出，产前和产后暴露于PM2.5与AR的后期发展有关。易受影响的时间窗口可能是在妊娠晚期和生命的第一年内。仍旧需要进一步的研究来确认AR对PM2.5的易感时期。

原始出处：

Yu-Ting Lin ， Hao Shih ， Chau-Ren Jung et al. Effect of exposure to fine particulate matter during pregnancy and infancy on paediatric allergic rhinitis. Thorax. Mar 2021

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#插入话题

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2021-07-18 hongbochen

#过敏性#

24 0
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2021-09-23 ms8435843352634314

#细颗粒物#

39 0
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2021-07-02 lisa449

#颗粒物#

40 0
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2021-05-26 ms1000001436543258

厉害了

62 0
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2021-03-18 108807375_62823133

#婴儿期#

0 0
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2021-03-17 ms1000000750365045

很好，谢谢

88 0
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2021-03-17 330911029

挺不错的

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