Hypertension:阻塞性睡眠呼吸暂停患者白天被动睡眠也容易发生高血压

2016-10-20 xing.T MedSci原创

OSA

由此可见,OSA患者白天被动睡眠也与高血压相关。

白天主动睡眠是阻塞性睡眠呼吸暂停(OSA)患者高血压的重要危险因素。最近心血管权威杂志《Hypertension》上发表中国学者的研究文章,旨在明确OSA患者白天被动睡眠与高血压的关系。

在这项研究中,研究者通过多次睡眠潜伏期试验测得OSA患者白天被动睡眠情况,研究共纳入1338例OSA患者和484例原发性打鼾患者,所有的研究对象接受一晚的多导睡眠图检测后进行多次睡眠潜伏期试验。多次睡眠潜伏期试验值分为3类:<5分钟,5-8分钟,>8分钟。高血压是基于直接血压测量值或医生的诊断。控制混杂因素后,相比于多次睡眠潜伏期试验值>8分钟的原发性打鼾患者,多次睡眠潜伏期试验值在5-8分钟的OSA患者发生高血压的可能性增加了95%(比值比为1.95;95%置信区间为1.10–3.46),而多次睡眠潜伏期试验值<5分钟的OSA患者发生高血压的几率进一步增加达111%(比值比为2.11;95%置信区间为1.22–3.31)。在分层分析中,研究者发现不同性别、年龄、有无肥胖以及过度的白天主动睡眠,OSA患者多次睡眠潜伏期试验与高血压均存在相关性。

由此可见,OSA患者白天被动睡眠也与高血压相关。

原始出处:

Rong Ren,et al. Obstructive Sleep Apnea With Objective Daytime Sleepiness Is Associated With Hypertension. Hypertension. 2016.

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    2016-11-20 feather89
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    2017-09-17 tomyang96
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    2016-11-02 xyfg98

    谢谢分享!

    0

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