Nutr Metab Cardiovas:体重正常仍然三高 原来是体脂率在捣鬼

2018-10-27 吴星 环球医学网

肥胖已成为全球范围内非常常见的疾病,超重和肥胖则是死亡的第五大风险因素。虽然目前体重指数(BMI)是超重和肥胖的标准诊断评估方法,但其不能准确评估身体脂肪率(BF%)。已有研究表明,一些BMI≥30kg/m2的患者代谢正常,而一些BMI仅为18.5~30.0kg/m2的患者却代谢异常。因此,随着相关研究的进展,BMI用于评估肥胖不断受到挑战。

肥胖已成为全球范围内非常常见的疾病,超重和肥胖则是死亡的第五大风险因素。虽然目前体重指数(BMI)是超重和肥胖的标准诊断评估方法,但其不能准确评估身体脂肪率(BF%)。已有研究表明,一些BMI≥30kg/m2的患者代谢正常,而一些BMI仅为18.5~30.0kg/m2的患者却代谢异常。因此,随着相关研究的进展,BMI用于评估肥胖不断受到挑战。

2018年10月,中国学者在《Nutr Metab Cardiovasc Dis》发表了一项全国性研究,考察了中国人群正常体重肥胖(NWO)的患病率,及其与心脏代谢风险的相关性。

数据来自于2007~2008年中国全国糖尿病和代谢疾病研究。使用生物阻抗法测量体脂(BF)。NWO的定义为,BMI正常(18.5~23.9kg/m2)但BF%过量(男性BF%≥24%,女性≥33%)。

纳入了23748人(男性9633人,女性14115人),男性NWO的患病率为9.5%,女性为6.06%。

研究结果显示,与正常组相比,NWO组的糖尿病、弗拉明汉风险评分(FRS)≥10%、高血压代谢综合征患病风险显着增加。

亚组分析表明,排除了腰围异常的参与者后,男性组与总人群的结果相似;但女性组中,FRS≥10%者高血压代谢综合征的患病风险增加,而糖尿病风险并无增加。

总之,在中国人群中,NWO的患病率相对较高,且中国男性的NWO患病率高于中国女性。NOW人群心脏代谢风险均显着增加,在排除腹部肥胖的影响后该风险仍然持续存在。

研究表明,文献报告的NWO患病率差别较大,女性为2%~31%,男性为0.7%~28%。除了研究人群的种族差异外,BF%临界值的不同也可能是患病率变化的一个重要原因。因此,研究者使用了几种不同的诊断标准进行分析。分析表明,NWO的患病率在4.52%~9.68%之间,表明中国人群NWO的患病率较高,有必要进行NWO筛查

原始出处:
Jia A1, Xu S2, Xing Y3, et al.Prevalence and cardiometabolic risks of normal weight obesity in Chinese population: A nationwide study.Nutr Metab Cardiovasc Dis. 2018 Oct;28(10):1045-1053. doi: 10.1016/j.numecd.2018.06.015. Epub 2018 Jun 25.

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    2019-06-10 一闲
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    2018-12-01 guojianrong
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