ARCH PATHOL LAB MED:妊娠滋养细胞肿瘤

2019-02-03 MedSci MedSci原创

妊娠滋养细胞肿瘤包括3个不同的实体:妊娠绒毛膜癌,胎盘部位滋养细胞肿瘤和上皮样滋养细胞肿瘤。因此,准确的诊断对于患者的临床管理很重要。本研究的目的是回顾妊娠滋养细胞肿瘤的临床特征和病理诊断。文献和个人经验是本研究的来源。

滋养细胞瘤是现代医学中少见的肿瘤,是临床实践中对持续妊娠期滋养细胞瘤的监测和早期化疗干预的结果。对这些肿瘤的诊断识别需要高度怀疑,并对其组织学特征的认识,以及免疫组织化学和分子生物标志物的适当应用。近年来,一些妊娠滋养细胞肿瘤的前体病变受到关注,包括早期/原位绒毛膜癌和不典型胎盘部位结节。

原始出处:

Pei Hui, Gestational Trophoblastic Tumors: A Timely Review of Diagnostic Pathology

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    2019-04-09 yb6560
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郭瑞霞教授:妊娠滋养细胞肿瘤,可被化疗攻克的癌症

妊娠滋养细胞肿瘤是胚胎的滋养细胞发生恶变而形成的肿瘤,有一半由葡萄胎恶化发展而来。因人种的差异,其在黄种人的发病率要高于其他人种,随着我国二孩政策开放,高龄妊娠妇女增加,近年发病率又有抬头趋势。因为妊娠滋养细胞肿瘤对化疗的高度敏感性,使之成为迄今为止化疗治疗效果最好的肿瘤,疾病缓解率可达80%以上,即将被攻克。