Obstet Gynecol:严重冠状病毒感染的妊娠结局

2020-06-16 MedSci原创 MedSci原创

妊娠期间SARS-CoV、MERS-CoV和SAR-CoV-2感染的病例报告数据有限,但它们可能会指导早期公共卫生行动和COVID-19的临床决策。

为充分了解当前的2019冠状病毒疾病(COVID-19)爆发,近日,妇产科权威杂志Obstetrics and Gynecology上发表了一篇研究文章,研究人员对报道在妊娠期间感染中东呼吸综合征冠状病毒(MERS-CoV)、严重急性呼吸综合征冠状病毒(SARS-CoV)和严重急性呼吸道综合征冠状病毒2(SARS-CoV-2)和引起COVID-19病毒病例的研究进行了系统评价,旨在概述临床表现、病程以及妊娠和新生儿结局。

研究人员检索了MEDLINE和ClinicalTrials.gov,检索时间从数据库成立到2020年4月23日。研究人员纳入了报道感染MERS-CoV、SARS-CoV和SARS-CoV-2孕妇的文献。从纳入的文章中摘录了病程、严重疾病的指标、孕产妇健康结局和妊娠结局。

研究人员确定了1328篇独特的文献,其中1253篇文献通过标题和摘要审阅被排除。研究人员完成了75篇文献的全文检索,其中29篇文章通过全文检索后被排除。在报告病例水平数据的46项文献中,有8项描述了12例MERS-CoV感染病例,有7项描述了17例SARS-CoV感染病例,还有31项描述了98例SARS-CoV-2感染病例。临床表现和病程从无症状到严重致命疾病不等,与一般患者相似。在妊娠期间感染MERS-CoV、SARS-CoV或SARS-CoV-2感染孕妇中报道了严重发病和死亡情况,以及不良的妊娠结局,包括流产、早产和母婴垂直传播。

由此可见,必须了解孕妇是否可能因严重的冠状病毒感染而产生不良的母婴结局。妊娠期间SARS-CoV、MERS-CoV和SAR-CoV-2感染的病例报告数据有限,但它们可能会指导早期公共卫生行动和COVID-19的临床决策。需要捕获关键数据才能更好地确定这种感染如何影响孕妇和新生儿。

原始出处:

Galang, Romeo R.et al.Severe Coronavirus Infections in Pregnancy A Systematic Review.Obstetrics & Gynecology.2020.https://journals.lww.com/greenjournal/Abstract/9000/Severe_Coronavirus_Infections_in_Pregnancy__A.97313.aspx

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (4)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1636212, encodeId=f0821636212d5, content=<a href='/topic/show?id=26eb3092232' target=_blank style='color:#2F92EE;'>#冠状病毒感染#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=30922, encryptionId=26eb3092232, topicName=冠状病毒感染)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=53a422597656, createdName=zjshifan_98647313, createdTime=Sun Oct 11 10:56:07 CST 2020, time=2020-10-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2044137, encodeId=9120204413ea6, content=<a href='/topic/show?id=8513126129d' target=_blank style='color:#2F92EE;'>#NEC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12612, encryptionId=8513126129d, topicName=NEC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1ac22500003, createdName=1249842em09(暂无昵称), createdTime=Fri Mar 12 18:56:07 CST 2021, time=2021-03-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2011429, encodeId=d21720114295d, content=<a href='/topic/show?id=840d1e300e5' target=_blank style='color:#2F92EE;'>#TET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=17300, encryptionId=840d1e300e5, topicName=TET)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=cc52251, createdName=yhy100200, createdTime=Sun Feb 07 04:56:07 CST 2021, time=2021-02-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1392965, encodeId=9f721392965bb, content=<a href='/topic/show?id=8c9f4492370' target=_blank style='color:#2F92EE;'>#妊娠结局#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=44923, encryptionId=8c9f4492370, topicName=妊娠结局)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1fa82500120, createdName=12498a1cm67暂无昵称, createdTime=Thu Jun 18 11:56:07 CST 2020, time=2020-06-18, status=1, ipAttribution=)]
  2. [GetPortalCommentsPageByObjectIdResponse(id=1636212, encodeId=f0821636212d5, content=<a href='/topic/show?id=26eb3092232' target=_blank style='color:#2F92EE;'>#冠状病毒感染#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=30922, encryptionId=26eb3092232, topicName=冠状病毒感染)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=53a422597656, createdName=zjshifan_98647313, createdTime=Sun Oct 11 10:56:07 CST 2020, time=2020-10-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2044137, encodeId=9120204413ea6, content=<a href='/topic/show?id=8513126129d' target=_blank style='color:#2F92EE;'>#NEC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12612, encryptionId=8513126129d, topicName=NEC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1ac22500003, createdName=1249842em09(暂无昵称), createdTime=Fri Mar 12 18:56:07 CST 2021, time=2021-03-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2011429, encodeId=d21720114295d, content=<a href='/topic/show?id=840d1e300e5' target=_blank style='color:#2F92EE;'>#TET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=17300, encryptionId=840d1e300e5, topicName=TET)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=cc52251, createdName=yhy100200, createdTime=Sun Feb 07 04:56:07 CST 2021, time=2021-02-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1392965, encodeId=9f721392965bb, content=<a href='/topic/show?id=8c9f4492370' target=_blank style='color:#2F92EE;'>#妊娠结局#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=44923, encryptionId=8c9f4492370, topicName=妊娠结局)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1fa82500120, createdName=12498a1cm67暂无昵称, createdTime=Thu Jun 18 11:56:07 CST 2020, time=2020-06-18, status=1, ipAttribution=)]
  3. [GetPortalCommentsPageByObjectIdResponse(id=1636212, encodeId=f0821636212d5, content=<a href='/topic/show?id=26eb3092232' target=_blank style='color:#2F92EE;'>#冠状病毒感染#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=30922, encryptionId=26eb3092232, topicName=冠状病毒感染)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=53a422597656, createdName=zjshifan_98647313, createdTime=Sun Oct 11 10:56:07 CST 2020, time=2020-10-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2044137, encodeId=9120204413ea6, content=<a href='/topic/show?id=8513126129d' target=_blank style='color:#2F92EE;'>#NEC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12612, encryptionId=8513126129d, topicName=NEC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1ac22500003, createdName=1249842em09(暂无昵称), createdTime=Fri Mar 12 18:56:07 CST 2021, time=2021-03-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2011429, encodeId=d21720114295d, content=<a href='/topic/show?id=840d1e300e5' target=_blank style='color:#2F92EE;'>#TET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=17300, encryptionId=840d1e300e5, topicName=TET)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=cc52251, createdName=yhy100200, createdTime=Sun Feb 07 04:56:07 CST 2021, time=2021-02-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1392965, encodeId=9f721392965bb, content=<a href='/topic/show?id=8c9f4492370' target=_blank style='color:#2F92EE;'>#妊娠结局#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=44923, encryptionId=8c9f4492370, topicName=妊娠结局)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1fa82500120, createdName=12498a1cm67暂无昵称, createdTime=Thu Jun 18 11:56:07 CST 2020, time=2020-06-18, status=1, ipAttribution=)]
    2021-02-07 yhy100200
  4. [GetPortalCommentsPageByObjectIdResponse(id=1636212, encodeId=f0821636212d5, content=<a href='/topic/show?id=26eb3092232' target=_blank style='color:#2F92EE;'>#冠状病毒感染#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=30922, encryptionId=26eb3092232, topicName=冠状病毒感染)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=53a422597656, createdName=zjshifan_98647313, createdTime=Sun Oct 11 10:56:07 CST 2020, time=2020-10-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2044137, encodeId=9120204413ea6, content=<a href='/topic/show?id=8513126129d' target=_blank style='color:#2F92EE;'>#NEC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12612, encryptionId=8513126129d, topicName=NEC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1ac22500003, createdName=1249842em09(暂无昵称), createdTime=Fri Mar 12 18:56:07 CST 2021, time=2021-03-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2011429, encodeId=d21720114295d, content=<a href='/topic/show?id=840d1e300e5' target=_blank style='color:#2F92EE;'>#TET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=17300, encryptionId=840d1e300e5, topicName=TET)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=cc52251, createdName=yhy100200, createdTime=Sun Feb 07 04:56:07 CST 2021, time=2021-02-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1392965, encodeId=9f721392965bb, content=<a href='/topic/show?id=8c9f4492370' target=_blank style='color:#2F92EE;'>#妊娠结局#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=44923, encryptionId=8c9f4492370, topicName=妊娠结局)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1fa82500120, createdName=12498a1cm67暂无昵称, createdTime=Thu Jun 18 11:56:07 CST 2020, time=2020-06-18, status=1, ipAttribution=)]

相关资讯

J Hypertens:妊娠早期接触比索洛尔后的妊娠结局

由此可见,该研究结果支持这样的假设即妊娠早期服用比索洛尔治疗不会增加自然流产或重大先天性缺陷的风险。然而,不能排除长期比索洛尔暴露对胎儿生长的影响。

JCEM:妊娠早期甲状腺功能和TPOAb对妊娠结局的影响

由此可见,妊娠早期TSH为2.5-4.08 mIU/L联合TPOAb(-)与流产和孕产妇综合结局相关。在TSH为2.5-4.08 mIU/L的孕妇中使用L-T4的优缺点仍不确定。

Eur Respir J:妊娠期哮喘急性发作对女性妊娠结局的影响

由此可见,妊娠期间AE的妇女发生妊娠并发症、围产期不良结局和其子女儿童早期患呼吸系统疾病的风险增加,表明适当的哮喘治疗可能会降低不良健康结局的风险。

Diabetologia:基于胰岛素抵抗的妊娠期糖尿病亚型的特征和妊娠结局

本研究旨在基于胰岛素抵抗确定妊娠期糖尿病(GDM)不同亚型的特征和妊娠结局。

Heart:瓣膜疾病女性的妊娠结局

由此可见,中度/重度MS和AS的女性具有不良的孕产妇和胎儿/新生儿结局风险。他们应由具有妊娠和心脏病经验的团队进行孕前咨询和怀孕护理。