Heart:院外心脏骤停后的长期生存情况如何?

2017-03-07 xing.T MedSci原创

出院后回家的OHCA幸存者经历了相对良好的长期生存。而围心脏骤停因素对出院后长期生存的影响较小,出院后恢复良好是与改善的长期预后相关。

虽然院外心脏骤停(OHCA)短期生存的相关因素已众所周知,而然对OHCA患者长期生存的影响因素知之甚少。近日,在心脏病领域权威杂志Heart上发表了一篇研究文章。在这项研究中,研究人员描述了OHCA幸存者的15年生存结局,并且评估围心脏骤停因素和12个月结局对长期生存率的影响。

研究人员纳入了在2000年至2014年之间经维多利亚急救心脏骤停注册中心(该中心与全州死亡记录相链接)确认的OHCA幸存者。研究人员采用Kaplan Meier生存曲线和Cox回归模型来估计的参与者的长期生存结局。

该研究共纳入了3449例患者,其平均生存时间为11.9年(95% 可信区间为11.7-12.1年)。1年生存率为92.2%(95% 可信区间为91.3%-93.1%),而5、10和15年的生存率分别为81.4%(95% 可信区间为79.9%-82.8%)、70.1%(95% 可信区间为67.9%-72.1%)和62.3%(95% 可信区间为58.9%-65.5%)。在心脏骤停后第一年,OHCA幸存者标准化死亡率为标准的澳大利亚人群的5.6倍,但在心脏骤停后第5年接近的标准人群。少数围心脏骤停因素与出院后长期生存独立相关。相反,运输到可以进行经皮冠状动脉介入治疗的医院和出院后回家与长寿相关。返回工作和良好的身体/功能恢复与12个月后改善的生存相关。

出院后回家的OHCA幸存者经历了相对良好的长期生存。而围心脏骤停因素对出院后长期生存的影响较小,出院后恢复良好是与改善的长期预后相关。

原始出处:

Emily Andrew,et al. Long-term survival following out-of-hospital cardiac arrest. Heart. 2017. http://dx.doi.org/10.1136/heartjnl-2016-310485

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    2017-03-10 jiuling

    学习了谢谢分享

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    2017-03-09 zhaojie88
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    2017-03-09 slcumt
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