心脏射频消融手术视频详解,4招识别复发风险!

2021-10-17 医格心领域 医格心领域

心房颤动(atrial fibrillation,AF)是一种最为常见的心律失常疾病,简称房颤,常见于冠状动脉硬化性心脏病(冠心病)、 瓣膜病和高血压病,也可单独发生,即特发性房颤或孤立性房颤。

心房颤动(atrial fibrillationAF)是一种最为常见的心律失常疾病,简称房颤,常见于冠状动脉硬化性心脏病(冠心病) 瓣膜病和高血压病,也可单独发生,即特发性房颤或孤立性房颤。

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射频导管消融术(radiofrequency catheter ablationRFCA)是治疗心房颤动的有效手段,是针对心房肌局部解剖的电活动异常,采取热能或冷冻方式使局部心肌坏死,从而达到根治的目的。RFCA在很多方面均优于抗心律失常药物,是治疗药物难治的阵发性和持续性AF的重要治疗方法。

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01 RFCA手术过程

过程:股静脉穿刺→送入导管→导管在房间隔进行穿刺→肺静脉开口处消融

房间隔穿刺

肺静脉处消融

消融成功后

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房间隔穿刺

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肺静脉处消融

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消融成功后

02 哪些人适合RFCA

1、心房颤动(房颤):对于有症状的阵发性房颤患者最适合;持续性房颤患者也是适合的,尤其是在抗心律失常药物效果欠佳的患者。

2、房室折返型心动过速(预激综合征)

3、房室结折返型心动过速

4、心房扑动(房扑)

5、房性心动过速(房速)

6、室性期前收缩(早搏)

7、室性心动过速(室速):包括特发性、束支折返性和疤痕性室速等。

03 RFCA效果如何?

阵发性心房颤动射频消融术的成功率85%左右,而持续性心房颤动,因采取的手术方式不一样,成功率有差别,在60%-80%

典型心房扑动、室上性心动过速,射频消融成功率可以达到95%以上,且可以起到根治性治疗。

房室结折返性心动过速、预激综合征等心律失常一次射频消融成功率可以达到98%以上。

04 RFCA术中需注意什么?

1、疼痛:由于RFCA术中病人保持清醒,因此病人不同人对疼痛的耐受程度不同。术中常规使用镇痛药物,大部分患者是可以耐受的,如果实在忍受不了,可以和医生沟通增加疼痛药物的使用量或者全麻下进行手术。消融时有可能会累及神经节分布区域,疼痛会比较剧烈,但这些部位往往是手术的关键区域。

2、平静呼吸:部分患者由于不能耐受疼痛,容易深呼吸(大喘气)或者屏气(憋住气)来缓解疼痛,容易导致术中扭动身体。而RFCA需要配合三维心脏模型开展,一旦身体扭动,医生需要重新建立心脏模型,势必会延长手术时间,增加不必要的痛苦。因此在术中平静呼吸非常重要有利于手术安全、顺利的开展。

3、咳嗽:如果想咳嗽,一定要提前和医生说明,否则咳嗽时不巧导管在心脏薄弱位置,咳嗽时产生的巨大压力容易戳破心脏。术中如果想咳嗽,也不能太用力,轻轻的咳,避免发生危险。

05 RFCA术后需注意什么?

1、穿刺后制动:射频消融术前需在大腿双侧进行静脉穿刺,术中为预防血栓形成使用抗凝药物,因此术后需在穿刺处用0.5KG的沙袋压迫2-6小时,双腿制动6-10小时,之后方可下地活动。需注意,术后平卧并非越长越好,平卧时间过长可能增加血栓栓塞的风险。平卧时可在床上做一些足部和脚趾的活动来预防血栓形成。

2、服用抗凝药物:阵发性房颤术后抗凝的时间一般在3个月左右,而持续性房颤抗凝时间一般更长,需要结合患者的自身情况、术中情况和术后心律而定,其时间在3个月至终身不等。

3、服用抗心律失常药物:无论是阵发性房颤还是持续性房颤,术后胺碘酮的服用时间一般都在3个月左右,有极少数患者会在复查时将胺碘酮服用时间延长为半年。

4、复查心电图:术后1~2周复查心电图,之后每1~3个月再次复查,连续监测半年。

06 如何判断RFCA术后复发风险?

1、肾小球滤过率(eGFR):房颤复发随着肾功能的恶化而逐渐增加,eGFR82.5 ml*mir-1*1.73m-2时,对房颤复发具有良好的预测价值。在肾功能正常、轻、中、重度CKD分型中,房颤复发率分别为11.5%29.3%72.0%93.3%,复发风险分别高出3倍、6倍和12倍。

2、血脂异常:来自 MESA-FHS队列的联合分析显示,高密度脂蛋白胆固醇 甘油三酯与房颤的复发相关。高密度脂蛋白≥60 mg/dL和甘油三酯< 40 mg/dL与较低的AF风险相关(风险比为 0.64),高甘油三酯与较高的AF风险相关(风险比为1.60)。

3、胱抑素C:胱抑素C水平越低,房颤复发的可能性越小。研究发现,消融前胱抑素C 水平与射频消融术后房颤复发相关,最佳截断值为1.190 mg/L,胱抑素C可能是比心脏结构改变或其他炎性标志物更敏感地预测消融后房颤复发的指标。

4、左心房(LA)容量:LA容量已被证明与房颤复发风险相关,LA内的瘢痕组织被认为是房颤复发的关键驱动因素,研究表明LA瘢痕(平均覆盖 LA表面的21.11%)的患者是房颤复发的唯一独立预测因子。

参考文献:

1LawrenceRosenthal . What is the success rate of ablation of atrial fibrillation (Afib)(AF) and who are potential candidates?medscap.Updated: Nov18, 2019.

2DengH,  Shantsila A,  Xue Y, et al.  Renal function andoutcomes after  catheter  ablation of  patients  with atrial  fibrillation  The Guangzhou  atrial fibrillation  ablation  registry [J]. Arch  Cardio- vasc Dis, 2019,112(6-7) 420-429

3、崔婷,黄织春.心房颤动射频消融复发的临床研究进展. [J].中国血管病研究,2020182):176-179.

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    溶酶生成后迅速与a2纤溶酶抑制剂1:1结

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  5. [GetPortalCommentsPageByObjectIdResponse(id=1905591, encodeId=ffd7190559100, content=<a href='/topic/show?id=0eb34259ea1' target=_blank style='color:#2F92EE;'>#复发风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=42597, encryptionId=0eb34259ea1, topicName=复发风险)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ca20190, createdName=wushaoling, createdTime=Sun Jan 09 04:20:34 CST 2022, time=2022-01-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1279968, encodeId=511212e996882, content=<a href='/topic/show?id=0b0546822fd' target=_blank style='color:#2F92EE;'>#射频消融#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=46822, encryptionId=0b0546822fd, topicName=射频消融)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=dc7a157, createdName=jinweidong, createdTime=Tue Oct 19 11:20:34 CST 2021, time=2021-10-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1421875, encodeId=641e14218e535, content=<a href='/topic/show?id=4bc865819d2' target=_blank style='color:#2F92EE;'>#消融#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=65819, encryptionId=4bc865819d2, topicName=消融)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=1a193676008, createdName=xiangyuzhou972, createdTime=Tue Oct 19 11:20:34 CST 2021, time=2021-10-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1061392, encodeId=63221061392b4, content=溶酶生成后迅速与a2纤溶酶抑制剂1:1结, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIrrxxDxnLic8t6EAs38Qfwo6H2h6JMleIgb9OSYf6LMnVDkQEqUXWoSDWboibjhOBI9SJDTXweqQIA/132, createdBy=50aa5321359, createdName=查查佳佳, createdTime=Mon Oct 18 08:56:09 CST 2021, time=2021-10-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1061315, encodeId=5cc21061315f3, content=感谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a4d75638647, createdName=YHW, createdTime=Sun Oct 17 22:06:36 CST 2021, time=2021-10-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1061298, encodeId=9cac10612984a, content=学到很多,感谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ac5e2550940, createdName=哈哈哈不知道呀, createdTime=Sun Oct 17 20:29:36 CST 2021, time=2021-10-17, status=1, ipAttribution=)]
    2021-10-17 YHW

    感谢

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  6. [GetPortalCommentsPageByObjectIdResponse(id=1905591, encodeId=ffd7190559100, content=<a href='/topic/show?id=0eb34259ea1' target=_blank style='color:#2F92EE;'>#复发风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=42597, encryptionId=0eb34259ea1, topicName=复发风险)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ca20190, createdName=wushaoling, createdTime=Sun Jan 09 04:20:34 CST 2022, time=2022-01-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1279968, encodeId=511212e996882, content=<a href='/topic/show?id=0b0546822fd' target=_blank style='color:#2F92EE;'>#射频消融#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=46822, encryptionId=0b0546822fd, topicName=射频消融)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=dc7a157, createdName=jinweidong, createdTime=Tue Oct 19 11:20:34 CST 2021, time=2021-10-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1421875, encodeId=641e14218e535, content=<a href='/topic/show?id=4bc865819d2' target=_blank style='color:#2F92EE;'>#消融#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=65819, encryptionId=4bc865819d2, topicName=消融)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=1a193676008, createdName=xiangyuzhou972, createdTime=Tue Oct 19 11:20:34 CST 2021, time=2021-10-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1061392, encodeId=63221061392b4, content=溶酶生成后迅速与a2纤溶酶抑制剂1:1结, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIrrxxDxnLic8t6EAs38Qfwo6H2h6JMleIgb9OSYf6LMnVDkQEqUXWoSDWboibjhOBI9SJDTXweqQIA/132, createdBy=50aa5321359, createdName=查查佳佳, createdTime=Mon Oct 18 08:56:09 CST 2021, time=2021-10-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1061315, encodeId=5cc21061315f3, content=感谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a4d75638647, createdName=YHW, createdTime=Sun Oct 17 22:06:36 CST 2021, time=2021-10-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1061298, encodeId=9cac10612984a, content=学到很多,感谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ac5e2550940, createdName=哈哈哈不知道呀, createdTime=Sun Oct 17 20:29:36 CST 2021, time=2021-10-17, status=1, ipAttribution=)]
    2021-10-17 哈哈哈不知道呀

    学到很多,感谢分享

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