Resp Med:老年人中不同肥胖指数与肺功能有何关系?

2017-12-26 安雅晶 环球医学

2017年发表在《Respir Med》的一项由中国和英国科学家进行的研究,考察了中国老年人中不同肥胖指数与肺功能的相关性,发现中国老年人核心肥胖及指数与较低的肺功能和较高的限制性呼吸缺陷风险相关。

2017年发表在《Respir Med》的一项由中国和英国科学家进行的研究,考察了中国老年人中不同肥胖指数与肺功能的相关性,发现中国老年人核心肥胖及指数与较低的肺功能和较高的限制性呼吸缺陷风险相关。

目的:研究人员考察了中国广州生物库队列研究(GBCS)中不同肥胖指数与肺功能的相关性。

方法:排除体质指数(BMI)<18.5(体重过低)的受试者。测量肥胖指数包括BMI、腰围(WC)、腰臀比、腰高比和体脂率。使用涡轮流量计评价肺功能。研究者分析了1秒用力呼气量(FEV1%)、用力肺活量(FVC%)和限制性呼吸缺陷(FEV1/FVC比>正常下限和FVC%<0.80)。

结果:在16186例受试者(平均年龄61.4 ± 7.2岁;74.0%为女性)中,116例(0.7%)受试者普通型肥胖(BMI≥28 kg/m2),4079例(25.2%)中心型肥胖(WC:男性≥90 cm,女性≥80 cm),1591例(9.8%)兼具两种肥胖类型。与核心和全身均不肥胖的受试者相比,中心型肥胖的受试者和兼具中心型和普通型肥胖的受试者肺功能更低(FEV1%和FVC%校正β范围-2.85至-6.02,校正OR范围1.14至1.70,均P<0.05)。普通型肥胖的受试者的肺功能较好,但不显着(FEV1%和FVC%粗β范围1.46至2.92,粗OR 范围0.68至0.93,均P>0.05)。肥胖指数增加每标准差,FEV1%和FVC%降低(校正β 范围-0.46至-3.17,均P<0.002)。中心型或普通型肥胖与限制性呼吸道缺陷呈正相关(校正比值比 (AOR)范围1.50至2.04,均P<0.002)。进一步校正WC反转了BMI与肺功能(校正β 范围1.93至6.22,均P<0.001)以及限制性呼吸缺陷(校正AOR范围0.72至0.80,均P<0.001)之间的逆相关。

结论:在中国老年人中,中心型肥胖及其指数而非普通型肥胖和BMI,与较低的肺功能和较高的限制性呼吸缺陷风险相关。

原始出处:
Pan J, Xu L, Lam TH, et al.Association of adiposity with pulmonary function in older Chinese: Guangzhou Biobank Cohort Study.Respir Med. 2017 Nov;132:102-108. doi: 10.1016/j.rmed.2017.10.003. Epub 2017 Oct 7.

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目前,有关疼痛对以后生活中性健康的影响的研究甚少。近期,一项发表在杂志Pain上的研究旨在明确老年男性和女性的自我报告疼痛与性健康之间的关系。此项研究收集了全国代表性英国老年纵向研究的数据。对社区居住的50岁及以上的成年人进行第6轮(2012/2013)性关系和活动问卷调查。询问他们是否经常“受到痛苦困扰”,他们的痛苦有多严重;轻度、中度或重度。疼痛和性健康之间的关联使用逻辑回归进行评估。分析按性

Nutrients:老年人容易缺什么?

已有的研究表明,老年人微量营养素亚临床缺乏症与老年慢性疾病和不良身体机能相关。