Diabetes Care:1型糖尿病血糖控制不佳与精神合并症的关系

2021-09-02 从医路漫漫 MedSci原创

糖尿病已成为全世界共同面临的一个的重大健康课题,它造成的损害累及全身多个器官和组织,无论直接还是间接地累及到中枢神经系统,都会导致精神症状的出现。

   糖尿病已成为全世界共同面临的一个的重大健康课题,它造成的损害累及全身多个器官和组织,无论直接还是间接地累及到中枢神经系统,都会导致精神症状的出现,其中抑郁状态是最常见的,其他疾病如神经衰弱综合征、焦虑、精神病性症状都可能出现,严重者可能出现糖尿病性脑病,最初以认知功能下降为主要表现,后期可以表现为类似痴呆综合征。   目的:我们调查了儿童人群中伴或不伴有精神疾病的预测因子和糖尿病结局的关系,认为1型糖尿病与精神疾病风险增加有关。   方法:收集了丹麦糖尿病登记处(DanDiabKids)和国家患者登记处(National Patient Register)儿童和青少年的数据(1996-2015年),基于这项人群进行研究。我们使用Kaplan-Meier图研究1型糖尿病发病时的年龄、1型糖尿病发病后2年内糖化血红蛋白(HbA1c)的平均水平(不包括首次的HbA1c)是否与合并精神疾病的风险相关。使用混合效应线性和logistic回归模型分析,将HbA1c、BMI、严重低血糖(SH)或酮症酸中毒和精神疾病的关系。   结果:在4725

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    2021-09-02 misszhang

    谢谢MedSci提供最新的资讯

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