Otol Neurotol:前庭神经鞘瘤中颅窝切除术后的听力保留分析

2022-02-05 AlexYang MedSci原创

描述了术前听力对中颅窝(MCF)入路切除前庭分裂瘤(VS)后听力保留可能性的影响,以及保留听力对疾病特异性生活质量(QOL)的影响。

前庭神经鞘瘤(VS)是位于桥小脑角(CPA)或内耳道(IAC)的良性、缓慢生长的肿瘤。目前,VS的发生率有所增加,可能是因为病人的寿命,症状教育以及听觉筛查和高分辨率对比增强磁共振成像(MRI)的使用。最常见的是CPA肿瘤,MRI的广泛使用使得较小管内肿瘤的诊断频率更高。

近期,来自美国的研究人员在《Otol Neurotol》上发表文章,描述了术前听力对中颅窝(MCF)入路切除前庭分裂瘤(VS)后听力保留可能性的影响,以及保留听力对疾病特异性生活质量(QOL)的影响

研究为回顾性的病历审查设计,依托学术性三级护理颅底手术项目。患者包括63名术前认字评分(WRS)≥50%的成年患者,他们在2017年至2020年间接受了MCF切除VS的手术。所有患者都接受了MCF VS切除术,并尝试保留听力。主要结果测量为听力保留(术后WRS≥50%),听力相关的彭氏听神经瘤生活质量(PANQOL)评分。

研究共分析了63名患者,平均年龄47.4(±9.6)岁,肿瘤大小11.5(±0.5)毫米。分别有37名(58.7%)和26名(41.3%)患者的听力得到保留(+HP)和丧失(-HP)。术前,+HP组的纯音平均听力(20.0分贝)明显低于-HP组(31.0分贝,P<0.003)。与-HP组相比,+HP组WRS较高(分别为94%和84%;P<0.002)。线性回归显示,管内与管外的肿瘤位置、突发性听力损失史、眼底液盖厚度和肿瘤大小与听力保存结果没有关系。在评估术后QOL数据时(n=37)发现,与听力有关的PANQOL评分在+HP和-HP组之间存在差异(t35=2.458,p=0.0191)。

人口统计学和临床特征

综上所述,在接受MCF切除VS的患者中,术前听力良好的患者HP率较高。术后,与-HP患者相比,+HP患者的听力相关PANQOL评分有所提高

原始出处:

Olivia A La Monte , Kareem O Tawfik, Usman Khan et al. Analysis of Hearing Preservation in Middle Cranial Fossa Resection of Vestibular Schwannoma. Otol Neurotol. Jan 2022

 

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    2022-02-11 妙医生

    好文!😄

    0

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    2022-02-07 ysjykql
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    2022-02-06 ms5000000518166734

    学习学习学习学习学习学习学习学习学习学习学习学习学习学习学习学习学习学习

    0

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