SciRep:光学相干断层扫描血管造影诊断慢性中心浆液性脉络膜视网膜病变中脉络膜新生血管情况

2019-06-28 MedSci 网络

台湾彰化基督教医院眼科的Wu JS等人在SciRep杂志上发表了一项重要的工作。他们通过光谱域光学相干断层扫描血管造影(OCTA)在慢性中心性浆液性脉络膜视网膜病变(CSC)(超过3个月)中检测脉络膜新生血管(CNV),比较这种方法新生血管的比例以及通过半剂量光动力疗法(PDT)治疗的比例。

台湾彰化基督教医院眼科的Wu JS等人在SciRep杂志上发表了一项重要的工作。他们通过光谱域光学相干断层扫描血管造影(OCTA)在慢性中心性浆液性脉络膜视网膜病变(CSC)(超过3个月)中检测脉络膜新生血管(CNV),比较这种方法新生血管的比例以及通过半剂量光动力疗法(PDT)治疗的比例。

所有患者随访至少12个月。使用光谱域OCT(SD-OCT,RTVue XR; Optovue)获得黄斑血管造影照片。外网状层和布鲁赫膜之间的外视网膜板中的血管被定义为CNV。比较CNV和非CNV组之间的临床特征。

研究群体包括61名患者(51名男性和10名女性)的70只眼睛。平均年龄为46.2岁。症状的平均持续时间为32.9个月。所有患者最初均接受半剂量PDT治疗。十一只眼睛(15.7%)接受了一次以上的PDT治疗。根据OCTA,70只眼中有32只(45.7%)被诊断为CNV。32只眼中只有6只(18.8%)需要玻璃体内抗血管内皮生长因子(VEGF)治疗。在CNV组中观察到年龄较大(p = 0.059)、较大的PDT斑点尺寸(p = 0.024)和较薄的中心凹下脉络膜厚度(p = 0.008)。

作者得出结论,OCTA显示出PDT治疗后与慢性CSC相关的CNV发生率较高。CNV组患者年龄较大,PDT斑点较大,中心凹下脉络膜厚度较薄。 OCTA可被认为是鉴定PDT治疗后慢性CSC中CNV的首要检测步骤。

原文出处:

Wu, J.S. and S.N. Chen, Optical Coherence Tomography Angiography for Diagnosis of Choroidal Neovascularization in Chronic Central Serous Chorioretinopathy after Photodynamic Therapy. Sci Rep, 2019. 9(1): p. 9040

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    2019-06-30 zutt
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    2019-06-30 sodoo
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    2019-06-29 百草

    666

    0

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    2019-06-28 医者仁心5538

    学习了

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