J Minim Invasive Gynecol:临床和宫腔镜特征预测癌前和恶性子宫内膜息肉

2019-06-15 sunshine MedSci原创

本研究旨在探究宫腔镜是否有助于诊断子宫内膜息肉中的恶性肿瘤。采用回顾性研究设计,纳入所有在2012年1月至2017年9月期间接受手术宫腔镜检查以切除子宫内膜息肉的妇女。对其医疗记录进行了审查,并提供了有关医疗,手术和产科病史以及宫腔镜检查结果(包括数量,大小和血管外观)的信息。息肉)是抽象的。对其进行子宫内膜息肉切除或活检的手术宫腔镜检查。该研究纳入了五百五十六名女性。他们的平均年龄为55.4±1

本研究旨在探究宫腔镜是否有助于诊断子宫内膜息肉中的恶性肿瘤。

采用回顾性研究设计,纳入所有在2012年1月至2017年9月期间接受手术宫腔镜检查以切除子宫内膜息肉的妇女。对其医疗记录进行了审查,并提供了有关医疗,手术和产科病史以及宫腔镜检查结果(包括数量,大小和血管外观)的信息。息肉)是抽象的。对其进行子宫内膜息肉切除或活检的手术宫腔镜检查。

该研究纳入了五百五十六名女性。他们的平均年龄为55.4±12.4岁,绝经期为322(57.9%)。在26例(4.7%)病例中发现子宫内膜癌,而在5例(0.9%)病例中发现子宫内膜增生。子宫内膜癌或增生与患者的年龄,绝经状态,宫腔镜检查时息肉血管增多以及宫腔镜检查中存在3个或更多息肉明显相关(所有比较p <.01)。然而,最大息肉的大小与子宫内膜癌或增生无关。在逻辑回归分析中,仅增加的息肉血管分布与子宫内膜癌或增生相关(优势比= 13.5; 95%置信区间,5.6-32.3; p <.001)。息肉血管性对非良性病变息肉诊断的敏感性,特异性,阳性预测值和阴性预测值分别为51.6%,94.3%,34.8%和97.1%。

综上所述,该研究结果表明,除了年龄和绝经状态等人口统计学参数外,宫腔镜检查发现子宫内膜息肉和许多子宫内膜息肉的血管分布增加可能提示恶性息肉的诊断。

原始出处:

Shor S, Pansky M, et al., Prediction of Premalignant and Malignant Endometrial Polyps by Clinical and HysteroscopicFeatures. J Minim Invasive Gynecol. 2019 Jan 4. pii: S1553-4650(19)30004-4. doi: 10.1016/j.jmig.2018.12.018. 


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