Eur J Oral Sci:空气研磨加活性玻璃改性或可提高种植体骨结合

2020-03-12 MedSci原创 MedSci原创

本研究旨在评估45S5生物活性玻璃,含锌生物活性玻璃或惰性玻璃在空气磨蚀后在喷砂和酸蚀钛表面上的人成骨样MC3T3-E1细胞的亲水性,表面自由能以及增殖和活力。

本研究旨在评估45S5生物活性玻璃,含锌生物活性玻璃或惰性玻璃在空气磨蚀后在喷砂和酸蚀钛表面上的人成骨样MC3T3-E1细胞的亲水性,表面自由能以及增殖和活力。

 

使用45S5生物活性玻璃,实验生物活性玻璃(Zn4)或惰性玻璃对喷砂和酸蚀的钛圆盘进行空气研磨。评价了接触角和表面自由能。使用成骨前细胞MC3T3-E1细胞研究试件表面。

 

结果显示,任一种类型的玻璃的空气磨蚀都显著提高了喷砂和酸蚀钛圆盘的亲水性和表面自由能。空气研磨掺有Zn4生物活性玻璃的基材的MC3T3-E1细胞数量更高,与硼硅酸盐盖玻片(对照组)相似。共聚焦激光扫描显微镜图像显示,MC3T3-E1细胞在喷砂,酸蚀和生物活性玻璃抛光表面上的扩散范围较对照组小。但是,对于45S5和Zn4处理的样品,细胞在24小时的时间点扩散最多,并且在进一步培养时其形态变为更多的纺锤状。

 

总之,研究表明,空气磨蚀可显著改变生物活性玻璃和惰性玻璃的表面润湿性和表面自由能。与使用惰性玻璃的空气研磨或不使用空气研磨的空气研磨相比,使用45S5生物活性玻璃和实验Zn4生物活性玻璃进行空气研磨可增强喷砂和酸蚀钛圆盘上的成骨细胞增殖。

 

原始出处:

 

Abushahba FTuukkanen J, et al., Effect of bioactive glass air-abrasion on the wettability and osteoblast proliferation on sandblasted and acid-etched titanium surfaces. Eur J Oral Sci. 2020 Mar 10. doi: 10.1111/eos.12683.

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    2020-12-28 小几洁
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    2020-12-04 huangdf
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