BMJ：新冠肺炎母婴垂直传播风险研究

2022-03-21 MedSci原创 MedSci原创

SARS-CoV-2感染产妇其后代SARS-CoV-2的阳性率较低，但现有证据证实了SARS-CoV-2的母婴垂直传播，母亲Covid-19的严重程度与后代的SARS-CoV-2阳性风险有关

随着新冠肺炎疫情的持续，孕妇感染风险不断增加，孕产妇感染SARS-CoV-2引发人们对新冠肺炎母婴传播可能性的担忧。SARS-CoV-2在普通人群中传播模式得到了充分研究，但产妇感染及其对后代影响的研究尚不充分。近日研究人员就SARS-CoV-2感染产妇后代婴儿的SARS-CoV-2阳性率、母婴传播可能性和围产期结局进行了研究。

本次研究为系统综述及荟萃分析，考察2019年12月1日至2021年8月3日之间相关研究数据，参与者为因任何原因接受治疗并诊断为SARS-CoV-2感染的孕妇，包括流产或流产后人群，并提供了关于后代SARS-CoV-2状态和阳性危险因素的数据。
总计472项研究纳入本次荟萃分析，包括206项队列研究，266例病例研究，包括28952 名孕妇和18237 名后代。总而言，SARS-CoV-2感染产妇所生的14271 名后代中，1.8%RT-PCR呈阳性。在592名SARS-CoV-2阳性婴儿中，14名确认为母婴传播，其中7名子宫内传播，2名分娩时传播，5名在产后早期。800名SARS-CoV-2阳性婴儿中，20名死产，23名新生儿死亡，8名早期流产，随访结束时，749名婴儿存活。孕产妇重症Covid-19（风险比2.4）、孕产妇新冠肺炎死亡（14.1）、孕产妇入住重症监护病房（3.5）和孕产妇产后感染（5）与后代SARS-CoV-2阳性相关。

母亲Covid-19的严重程度与后代的SARS-CoV-2阳性风险有关

研究认为，SARS-CoV-2感染产妇其后代SARS-CoV-2的阳性率较低，但现有证据证实了SARS-CoV-2的母婴垂直传播，母亲Covid-19的严重程度与后代的SARS-CoV-2阳性风险有关。
原始出处：
John Allotey et al. SARS-CoV-2 positivity in offspring and timing of mother-to-child transmission: living systematic review and meta-analysis. BMJ，16 March，2022.

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2022-09-20 394192432

借用，很有用

25 0
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2023-02-24 quxin068

#风险研究#

34 0
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2022-09-13 gaoxiaoe

#BMJ#

27 0
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2022-03-24 ms2000001386604039

学习

60 0
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2022-03-23 zhouqu_8

#母婴#

45 0
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2022-03-23 一闲

#垂直传播#

34 0
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2022-03-23 147760b0m84暂无昵称

学习了，谢谢

53 0
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2022-03-21 ms7000001578493802

很好

60 0
[GetPortalCommentsPageByObjectIdResponse(id=2089340, encodeId=4f102089340e7, content=借用，很有用, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=04514866935, createdName=394192432, createdTime=Tue Sep 20 14:32:32 CST 2022, time=2022-09-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2055734, encodeId=15642055e349e, content=<a href='/topic/show?id=734110089320' target=_blank style='color:#2F92EE;'>#风险研究#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100893, encryptionId=734110089320, topicName=风险研究)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=74808, createdName=quxin068, createdTime=Fri Feb 24 18:02:49 CST 2023, time=2023-02-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1849387, encodeId=a7cc184938e22, content=<a href='/topic/show?id=2977356edc' target=_blank style='color:#2F92EE;'>#BMJ#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3567, encryptionId=2977356edc, topicName=BMJ)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=148754, createdName=gaoxiaoe, createdTime=Tue Sep 13 18:02:49 CST 2022, time=2022-09-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1205425, encodeId=d30f1205425ce, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=1d465591916, createdName=ms2000001386604039, createdTime=Thu Mar 24 05:39:42 CST 2022, time=2022-03-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1439407, encodeId=2cd9143940eb2, content=<a href='/topic/show?id=45616352128' target=_blank style='color:#2F92EE;'>#母婴#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=63521, encryptionId=45616352128, topicName=母婴)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=zhouqu_8, createdTime=Wed Mar 23 10:02:49 CST 2022, time=2022-03-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1526048, encodeId=4e0d152604833, content=<a href='/topic/show?id=1005415189f' target=_blank style='color:#2F92EE;'>#垂直传播#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=41518, encryptionId=1005415189f, topicName=垂直传播)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=752811684847, createdName=一闲, createdTime=Wed Mar 23 10:02:49 CST 2022, time=2022-03-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1205084, encodeId=15121205084cf, content=学习了，谢谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1fa35218798, createdName=147760b0m84暂无昵称, createdTime=Wed Mar 23 00:25:45 CST 2022, time=2022-03-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1204738, encodeId=64ac1204e38aa, content=很好, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=af015636463, createdName=ms7000001578493802, createdTime=Mon Mar 21 21:17:07 CST 2022, time=2022-03-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1204736, encodeId=153e1204e36e1, content=学习～, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=cfb41991958, createdName=xulv123, createdTime=Mon Mar 21 21:09:14 CST 2022, time=2022-03-21, status=1, ipAttribution=)]
2022-03-21 xulv123

学习～

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