Preventive Medicine:超140万人群证实,儿童长期暴露于空气污染,自残风险增加50%!

2021-09-20 MedSci原创 MedSci原创

全世界有90%的人都在呼吸受到污染的空气。在世界卫生组织公布的2019十大健康威胁中,空气污染位列首位。流行病学发现长期暴露于空气污染与一系列疾病的发病率和死亡率有关。

全世界有90%的人都在呼吸受到污染的空气。在世界卫生组织公布的2019十大健康威胁中,空气污染位列首位。流行病学发现长期暴露于空气污染与一系列疾病的发病率和死亡率有关。

CCO

近日,发表在Preventive Medicine杂志的一项超过140万丹麦人的研究表明,童年时期接触两种常见污染物,包括PM 2.5NO 2 ,与成年自残的风险增加之间存在联系。

在这项研究中,研究人员使用丹麦民事登记系统数据,该数据包括所有在丹麦出生和移民人群,包括性别、出生日期和地点、父母的身份,以及关于生命健康状况和住址信息。研究纳入1979 年至 2006 年间在丹麦出生,在 10 岁生日时还活着并居住在丹麦,共超过 140 万人。

同时,研究人员跟踪每个人从出生到十岁生日的居住地点,以及每个地址居住的时间长度,进而评估了室外PM 2.5 NO 2水平与从 10 岁生日到 37 岁的后续自残风险。

环境室外空气污染由气体、颗粒物以及无机和有机化合物的复杂混合物组成。PM 2.5NO 2是对身体健康影响最大的污染物。这些气体的排放来源广泛,包括汽车尾气、发电、航运和家庭供暖。

研究结果显示,从出生到10岁生日,与每天暴露于低于13 μg/m 3PM2.5相比,露于19 μg/m 3或以上的儿童,自残风险高出48%,且PM2.5每增加5 μg/m 3,自残风险增加 42%

PM2.5和NO2暴露水平对成年自残风险的影响.

同样,从出生到10岁生日,与每天暴露于低于10 μg/m 3NO 2相比,每天暴露于25μg/m 3或以上,自残风险高出50%,且NO 2每增加10 μg/m 3,自残风险增加 21%

研究者表示,越来越多的证据表明,暴露于空气污染也与不良的心理健康结果有关。居住在空气污染程度较高的社区的儿童患一系列精神疾病的风险增加,包括精神分裂症、抑郁症和注意力缺陷多动障碍 (ADHD)等。

虽然尚未阐明,空气污染与精神障碍的发展和恶化的生物学机制,但已经确定它会导致炎症和氧化应激。这项研究首次为儿童暴露于空气污染与随后增加的自残风险之间的关联提供了宝贵的证据。然而,仍要进一步的研究,尤其是环境空气污染水平远高于丹麦的中低收入国家。

原始出处

Pearl L.H. Mok et al, Exposure to ambient air pollution during childhood and subsequent risk of self-harm: A national cohort study, Preventive Medicine (2021). DOI: 10.1016/j.ypmed.2021.106502

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    2022-01-22 kalseyzl
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    2022-01-10 lhlxtx
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    2021-12-07 jeanqiuqiu
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    2021-09-20 公子墨

    厉害👍

    0

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    2021-09-20 ms2000001764390960

    来好好学习一下

    0

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