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双抗体鸡尾酒疗法REGN-COV2：再生元启动针对新冠病毒COVID-19的首项临床研究

2020-06-11 MedSci原创 MedSci原创

新型冠状病毒COVID-19双抗体鸡尾酒疗法REGN-COV2首项临床研究
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REGN-COV2结合了两种抗体，它们非竞争性地与SARS-CoV-2病毒刺突蛋白的受体结合域结合，以降低突变病毒的逃逸。

再生元（Regeneron Pharmaceuticals）公司宣布，已开始对其双抗体混合物REGN-COV2用于预防和治疗新型冠状病毒COVID-19，开展首项临床研究。

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该公司指出，REGN-COV2结合了两种抗体REGN10933和REGN10987，它们非竞争性地与SARS-CoV-2病毒刺突蛋白的受体结合域（RBD）结合，以降低突变病毒的逃逸。

根据Regeneron的说法，REGN-COV2临床计划将由四个独立的研究人群组成，包括住院和非住院的新冠COVID-19感染患者、处​​于高风险暴露人群中的未感染人群和与COVID-19患者密切接触的未感染人群。

Regeneron的首席科学官George Yancopoulos表示，REGN-COV2具有“预防和治疗感染COVID-19的潜能，也有可能阻止病毒的逃逸”。

原始出处：

https://www.firstwordpharma.com/node/1731740?tsid=4

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    2020-12-22 黑布林

    积极配合

    0

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    2020-10-08 yyanpro@21cn.c

    #新冠病毒COVID-19#

    0

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    2020-06-13 yeye5224615

    #双抗#

    0

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    2020-06-13 12498768m17(暂无昵称)

    #鸡尾酒疗法#

    0

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    2020-06-13 qblt

    #鸡尾酒#

    0

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    2020-06-11 公卫新人

    新冠肺炎，疫情何时才能消失

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