Eur Urol:无症状性菌尿治疗的利弊:系统回顾和荟萃分析

2017-08-01 fengxiangxin MedSci原创

因为抗生素治疗的副作用以及抗生素耐药风险的存在,无症状性菌尿往往无需抗菌治疗。但是,凡事有利弊,研究者为了弄清楚无症状性菌尿抗菌治疗的利弊,在特定病人群体中进行了系统的回顾分析。研究者对相关数据库进行了检索,并对合格的试验的风险偏倚、推荐等级、发展和教育质量进行了评估。

因为抗生素治疗的副作用以及抗生素耐药风险的存在,无症状性菌尿往往无需抗菌治疗。但是,凡事有利弊,研究者为了弄清楚无症状性菌尿抗菌治疗的利弊,在特定病人群体中进行了系统的回顾分析。研究者对相关数据库进行了检索,并对合格的试验的风险偏倚、推荐等级、发展和教育质量进行了评估。

在筛选了3626篇文章之后,本次荟萃分析共纳入了50项涉及7088名患者的研究。总的来说,证据质量偏低,在没有危险因素的病人中,研究者没有发现治疗带来益处的证据(糖尿病患者、绝经后的妇女、老年弱势病人、肾移植患者、关节置换术患者),对于复发性尿路感染(UTI)患者,治疗是有害的。

无症状性菌尿治疗降低了经尿道电除术后的尿路感染风险。在怀孕妇女中,有证据表明治疗降低了症状性菌尿、低出生体重和早产的风险。

最后得出结论:对大多数人来说,抗菌治疗是无益的,并且可能是有害的。但是,对于无症状性菌尿的孕妇和那些即将接受泌尿外科手术的妇女抗生素治疗似乎是有利的。

原始出处:


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    2017-11-11 venlin
  3. 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    2018-02-26 lujian
  4. 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topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib2JlGvwpAibiaovVhfA9DbO7X7JLGGjM4Cic6oMgxLdnuS9piaP9cnG2OwIbkzHvX0qzS1boibyYNqR5vHZu7HQs5EIB/0, createdBy=298d1398341, createdName=lou.minghong, createdTime=Sun Aug 06 01:37:28 CST 2017, time=2017-08-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1484973, encodeId=750b14849e3c6, content=<a href='/topic/show?id=4bbe5902ed2' target=_blank style='color:#2F92EE;'>#无症状#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=59027, encryptionId=4bbe5902ed2, topicName=无症状)], attachment=null, authenticateStatus=null, createdAvatar=Bioon/avatar/20180429/70baad2aa5a046c5aa2914d262de7d37.jpg, createdBy=bd077990475, createdName=12498da4m34(暂无昵称), createdTime=Thu Aug 03 14:21:00 CST 2017, time=2017-08-03, status=1, ipAttribution=), 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createdBy=78cc1691107, createdName=龙胆草, createdTime=Thu Aug 03 08:58:27 CST 2017, time=2017-08-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=229034, encodeId=28ae229034ef, content=这算新观点吗, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=18741984753, createdName=smartxiuxiu, createdTime=Wed Aug 02 06:44:46 CST 2017, time=2017-08-02, status=1, ipAttribution=)]
    2017-08-09 139****9672

    学习了,不错啊

    0

  5. 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createdBy=78cc1691107, createdName=龙胆草, createdTime=Thu Aug 03 08:58:27 CST 2017, time=2017-08-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=229034, encodeId=28ae229034ef, content=这算新观点吗, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=18741984753, createdName=smartxiuxiu, createdTime=Wed Aug 02 06:44:46 CST 2017, time=2017-08-02, status=1, ipAttribution=)]
    2017-08-09 天涯183

    非常好的文章,学习了,很受益

    0

  6. 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createdBy=78cc1691107, createdName=龙胆草, createdTime=Thu Aug 03 08:58:27 CST 2017, time=2017-08-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=229034, encodeId=28ae229034ef, content=这算新观点吗, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=18741984753, createdName=smartxiuxiu, createdTime=Wed Aug 02 06:44:46 CST 2017, time=2017-08-02, status=1, ipAttribution=)]
    2017-08-06 lou.minghong

    学习了谢谢分享!

    0

  7. 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  8. 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topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib2JlGvwpAibiaovVhfA9DbO7X7JLGGjM4Cic6oMgxLdnuS9piaP9cnG2OwIbkzHvX0qzS1boibyYNqR5vHZu7HQs5EIB/0, createdBy=298d1398341, createdName=lou.minghong, createdTime=Sun Aug 06 01:37:28 CST 2017, time=2017-08-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1484973, encodeId=750b14849e3c6, content=<a href='/topic/show?id=4bbe5902ed2' target=_blank style='color:#2F92EE;'>#无症状#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=59027, encryptionId=4bbe5902ed2, topicName=无症状)], attachment=null, authenticateStatus=null, createdAvatar=Bioon/avatar/20180429/70baad2aa5a046c5aa2914d262de7d37.jpg, createdBy=bd077990475, createdName=12498da4m34(暂无昵称), createdTime=Thu Aug 03 14:21:00 CST 2017, time=2017-08-03, status=1, ipAttribution=), 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  9. 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createdBy=78cc1691107, createdName=龙胆草, createdTime=Thu Aug 03 08:58:27 CST 2017, time=2017-08-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=229034, encodeId=28ae229034ef, content=这算新观点吗, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=18741984753, createdName=smartxiuxiu, createdTime=Wed Aug 02 06:44:46 CST 2017, time=2017-08-02, status=1, ipAttribution=)]
    2017-08-03 龙胆草

    学习谢谢分享

    0

  10. 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createdBy=78cc1691107, createdName=龙胆草, createdTime=Thu Aug 03 08:58:27 CST 2017, time=2017-08-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=229034, encodeId=28ae229034ef, content=这算新观点吗, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=18741984753, createdName=smartxiuxiu, createdTime=Wed Aug 02 06:44:46 CST 2017, time=2017-08-02, status=1, ipAttribution=)]
    2017-08-02 smartxiuxiu

    这算新观点吗

    0

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