Support Care Cancer:运动康复对接受化疗放疗的头颈部癌症患者功能能力和生活质量的影响

2020-06-22 MedSci原创 MedSci原创

疲劳、功能下降、生活质量受损是化疗放疗(CRT)最常见的不良后果。头颈部癌症(HNC)在全球范围内影响了50多万人,其治疗对患者造成了沉重的伤害,常常影响到他们的语言、吞咽和呼吸功能,因此他们常常会出

疲劳、功能下降、生活质量受损是化疗放疗(CRT)最常见的不良后果。头颈部癌症(HNC)在全球范围内影响了50多万人,其治疗对患者造成了沉重的伤害,常常影响到他们的语言、吞咽和呼吸功能,因此他们常常会出现疲劳、抑郁和身体不活动。本研究旨在评价基于运动的康复治疗对CRT的HNC患者的功能能力、生活质量、疲劳、血红蛋白和血小板计数的效果。

 

研究对148名接受CRT的头颈癌患者进行随机分组,评价运动对6分钟步行测试测量的功能能力、医疗结果调查短表36 v2问卷测量的生活质量、NCCN(0-10)量表测量的疲劳、血红蛋白和血小板的效果。对照组接受了标准的体力活动建议,而运动组则接受了为期11周的有氧运动和主动阻力运动的结构化运动计划。

 

结果显示,运动组的功能能力(p<0.001)、生活质量(p<0.001)和预防疲劳恶化(p<0.001)均有显著改善。血液参数在对照组和运动组之间未见显著差异。

 

综上所述,该研究结果表明,对接受CRT的HNC患者进行为期11周的结构化运动计划有助于提高他们的功能能力和生活质量。同时也防止了运动组疲劳程度的恶化。

 

原始出处:

 

Stephen Rajan Samuel, Arun G Maiya, et al., Effectiveness of Exercise-Based Rehabilitation on Functional Capacity and Quality of Life in Head and Neck Cancer Patients Receiving Chemo-Radiotherapy.Support Care Cancer. 2019 Oct;27(10):3913-3920. doi: 10.1007/s00520-019-04750-z.  

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    2021-02-05 wetgdt
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    2020-06-24 wshxjq
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