Rom J Morphol Embryol :91岁女性患者患有结膜侵袭性低分化鳞状细胞癌

2018-07-01 cuiguizhong MedSci原创

罗马尼亚Grigore T. Popa医学的Todireasa AI近日在 Rom J Morphol Embryol发表了一篇文章,他们介绍了一名91岁患者的临床病例,该病人在罗马尼亚雅住院期间被Nicolae Oblu教授所在的第二眼科诊所诊断发现。该实体肿瘤块约为1×2厘米,这在鼻部右眼球结膜下。磁共振成像(MRI)检查显示右眼巩膜粘附肿瘤,侵入眼眶组织。

罗马尼亚Grigore T. Popa医学的Todireasa AI近日在 Rom J Morphol Embryol发表了一篇文章,他们介绍了一名91岁患者的临床病例,该病人在罗马尼亚雅住院期间被Nicolae Oblu教授所在的第二眼科诊所诊断发现。该实体肿瘤块约为1×2厘米,这在鼻部右眼球结膜下。磁共振成像(MRI)检查显示右眼巩膜粘附肿瘤,侵入眼眶组织。

眼球的侵袭性结膜鳞状细胞癌(SCC)是一种仅侵入结膜但很少侵入眼球和眼眶组织的恶性肿瘤。医生将右眼球与粘附肿瘤一起摘除,并且进行了附近眼窝组织部分剔除。病理学检查显示,抗细胞角蛋白AE1 / AE3抗体的免疫组织化学(IHC)反应为阳性,Ki67具有相对较高的标记指数,但其对人黑色素黑-45(HMB-45)的标记物不具有免疫反应性。组织病理学(HP)诊断为右眼结膜的SCC分化差,伴有角膜、巩膜和眼眶结缔组织和脂肪组织(pT4N0M0)的浸润。

这项研究表明,对对老年患者的侵入性结膜SCC的诊断需要提早进行,以防止眼部和眼眶的侵袭以及转移的出现。这种肿瘤在十年中很少发生,目前文献报道仅有三例。HP的病变检查是诊断的金标准,特别是当结合IHC染色时进行诊断。

原文出处:

Todireasa, A.I., et al., Conjunctival invasive poorly differentiated squamous cell carcinoma in a 91-year-old female patient. Rom J Morphol Embryol, 2018. 59(1): p. 375-380.

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    2018-07-03 sunyl07
  5. [GetPortalCommentsPageByObjectIdResponse(id=2033520, encodeId=d0312033520d4, content=<a href='/topic/show?id=446044648ad' target=_blank style='color:#2F92EE;'>#女性患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=44648, encryptionId=446044648ad, topicName=女性患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e0a1165, createdName=jiangfeng5067, createdTime=Thu Aug 16 01:29:00 CST 2018, time=2018-08-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1978710, encodeId=14bb19e8710cd, content=<a href='/topic/show?id=3b90e79787f' target=_blank style='color:#2F92EE;'>#细胞癌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=77978, encryptionId=3b90e79787f, topicName=细胞癌)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e457184, createdName=qingting, createdTime=Tue Jul 17 12:29:00 CST 2018, time=2018-07-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1923421, encodeId=73ed192342179, content=<a href='/topic/show?id=fa0d2615677' target=_blank style='color:#2F92EE;'>#低分化#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26156, encryptionId=fa0d2615677, topicName=低分化)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=85152500072, createdName=124987c6m36暂无昵称, createdTime=Thu Nov 29 08:29:00 CST 2018, time=2018-11-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1366305, encodeId=49b8136630552, content=<a href='/topic/show?id=186126998e2' target=_blank style='color:#2F92EE;'>#侵袭性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26998, encryptionId=186126998e2, topicName=侵袭性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1be8234, createdName=sunyl07, createdTime=Tue Jul 03 11:29:00 CST 2018, time=2018-07-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=328583, encodeId=9b05328583dd, content=厉害了我的哥, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib3IzoRn621JdKCFUI4XvNELcibocrAVU6aUzEVDSaf3rYH08PUYUiagGqxAEhj8g9WqqNvD1CupIpCrmnR2OrqHZh/0, createdBy=7f181365728, createdName=飛歌, createdTime=Mon Jul 02 00:20:59 CST 2018, time=2018-07-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=328547, encodeId=c48e32854ec2, content=很好的学习机会, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2018/04/12/cd30eefc465f70dc4dad89bd57479781.jpg, createdBy=02be2318568, createdName=一天没事干, createdTime=Sun Jul 01 22:22:24 CST 2018, time=2018-07-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=328545, encodeId=8a633285453d, content=不错的文章值得拥有., beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=eff51996281, createdName=1e1b8538m79(暂无匿称), createdTime=Sun Jul 01 22:17:47 CST 2018, time=2018-07-01, status=1, ipAttribution=)]
    2018-07-02 飛歌

    厉害了我的哥

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=2033520, encodeId=d0312033520d4, content=<a href='/topic/show?id=446044648ad' target=_blank style='color:#2F92EE;'>#女性患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=44648, encryptionId=446044648ad, topicName=女性患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e0a1165, createdName=jiangfeng5067, createdTime=Thu Aug 16 01:29:00 CST 2018, time=2018-08-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1978710, encodeId=14bb19e8710cd, content=<a href='/topic/show?id=3b90e79787f' target=_blank style='color:#2F92EE;'>#细胞癌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=77978, encryptionId=3b90e79787f, topicName=细胞癌)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e457184, createdName=qingting, createdTime=Tue Jul 17 12:29:00 CST 2018, time=2018-07-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1923421, encodeId=73ed192342179, content=<a href='/topic/show?id=fa0d2615677' target=_blank style='color:#2F92EE;'>#低分化#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26156, encryptionId=fa0d2615677, topicName=低分化)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=85152500072, createdName=124987c6m36暂无昵称, createdTime=Thu Nov 29 08:29:00 CST 2018, time=2018-11-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1366305, encodeId=49b8136630552, content=<a href='/topic/show?id=186126998e2' target=_blank style='color:#2F92EE;'>#侵袭性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26998, encryptionId=186126998e2, topicName=侵袭性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1be8234, createdName=sunyl07, createdTime=Tue Jul 03 11:29:00 CST 2018, time=2018-07-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=328583, encodeId=9b05328583dd, content=厉害了我的哥, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib3IzoRn621JdKCFUI4XvNELcibocrAVU6aUzEVDSaf3rYH08PUYUiagGqxAEhj8g9WqqNvD1CupIpCrmnR2OrqHZh/0, createdBy=7f181365728, createdName=飛歌, createdTime=Mon Jul 02 00:20:59 CST 2018, time=2018-07-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=328547, encodeId=c48e32854ec2, content=很好的学习机会, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2018/04/12/cd30eefc465f70dc4dad89bd57479781.jpg, createdBy=02be2318568, createdName=一天没事干, createdTime=Sun Jul 01 22:22:24 CST 2018, time=2018-07-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=328545, encodeId=8a633285453d, content=不错的文章值得拥有., beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=eff51996281, createdName=1e1b8538m79(暂无匿称), createdTime=Sun Jul 01 22:17:47 CST 2018, time=2018-07-01, status=1, ipAttribution=)]
    2018-07-01 一天没事干

    很好的学习机会

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=2033520, encodeId=d0312033520d4, content=<a href='/topic/show?id=446044648ad' target=_blank style='color:#2F92EE;'>#女性患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=44648, encryptionId=446044648ad, topicName=女性患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e0a1165, createdName=jiangfeng5067, createdTime=Thu Aug 16 01:29:00 CST 2018, time=2018-08-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1978710, encodeId=14bb19e8710cd, content=<a href='/topic/show?id=3b90e79787f' target=_blank style='color:#2F92EE;'>#细胞癌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=77978, encryptionId=3b90e79787f, topicName=细胞癌)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e457184, createdName=qingting, createdTime=Tue Jul 17 12:29:00 CST 2018, time=2018-07-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1923421, encodeId=73ed192342179, content=<a href='/topic/show?id=fa0d2615677' target=_blank style='color:#2F92EE;'>#低分化#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26156, encryptionId=fa0d2615677, topicName=低分化)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=85152500072, createdName=124987c6m36暂无昵称, createdTime=Thu Nov 29 08:29:00 CST 2018, time=2018-11-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1366305, encodeId=49b8136630552, content=<a href='/topic/show?id=186126998e2' target=_blank style='color:#2F92EE;'>#侵袭性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26998, encryptionId=186126998e2, topicName=侵袭性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1be8234, createdName=sunyl07, createdTime=Tue Jul 03 11:29:00 CST 2018, time=2018-07-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=328583, encodeId=9b05328583dd, content=厉害了我的哥, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib3IzoRn621JdKCFUI4XvNELcibocrAVU6aUzEVDSaf3rYH08PUYUiagGqxAEhj8g9WqqNvD1CupIpCrmnR2OrqHZh/0, createdBy=7f181365728, createdName=飛歌, createdTime=Mon Jul 02 00:20:59 CST 2018, time=2018-07-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=328547, encodeId=c48e32854ec2, content=很好的学习机会, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2018/04/12/cd30eefc465f70dc4dad89bd57479781.jpg, createdBy=02be2318568, createdName=一天没事干, createdTime=Sun Jul 01 22:22:24 CST 2018, time=2018-07-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=328545, encodeId=8a633285453d, content=不错的文章值得拥有., beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=eff51996281, createdName=1e1b8538m79(暂无匿称), createdTime=Sun Jul 01 22:17:47 CST 2018, time=2018-07-01, status=1, ipAttribution=)]
    2018-07-01 1e1b8538m79(暂无匿称)

    不错的文章值得拥有.

    0