JAMA Intern Med:浙江地区一次新冠肺炎公交车传播案例分析研究

2020-09-07 MedSci原创 MedSci原创

本次队列研究表明,与COVID-19确诊患者同乘的接触者感染SARS-CoV-2的风险更高,在高度封闭的环境中,必须考虑SARS-CoV-2病毒在空中传播的可能性

寻找严重急性呼吸系统综合征冠状病毒2型(SARS-CoV-2)气溶胶(即空气传播)传播的证据具有重大的公共卫生意义。近日研究人员利用COVID-19疫情的流行病学证据,探讨SARS-CoV-2感染的潜在传播途径。

研究人员分析了浙江省一次社区COVID-19疫情数据。在2020年1月19日,128人乘坐2辆公交车(60[46.9%]接触者来自公交车1,68[53.1%]接触者来自公交车2)往返100分钟,参加了一个150分钟的礼拜活动。在公交车2上有一名确诊患者。研究人员考察了乘坐公交车1(n=60)和公交车2(n=67[确诊病人除外])和所有其他参加礼拜活动的个人(n=172)感染SARS-CoV-2的风险。根据与确诊病人的距离将公交车座位分为高风险区和低风险区,在这两辆公交车上,中央空调都处于室内循环模式。研究的主要终点为核酸检测证实的SARS-CoV-2感染。

在128名接触者中,15名(11.7%)为男性,113名(88.3%)为女性,平均年龄为58.6岁。 在公交车2上,68名接触者中有24人(35.3%)在事件发生后确诊COVID-19,但与此同时,在公交车1的60名接触者中无一人感染。 在参与礼拜活动的172名接触者中,有7人(4.1%)感染。 在公交车2感染COVID-19的风险比在公交车1高34.3%,并且与参加礼拜活动的所有其他个体相比,患COVID-19的风险高11.4倍。在公交车2中,高风险区域的接触者与低风险区域的接触者相比,COVID-19感染风险中度提高但不显著。

公交车2接触者感染情况

本次队列研究表明,与COVID-19确诊患者同乘的接触者感染SARS-CoV-2的风险更高,在高度封闭的环境中,必须考虑SARS-CoV-2病毒在空中传播的可能性。

原始出处:

Ye Shen et al. Community Outbreak Investigation of SARS-CoV-2 Transmission Among Bus Riders in Eastern China. JAMA Intern Med. September 1, 2020.

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  3. [GetPortalCommentsPageByObjectIdResponse(id=2056374, encodeId=1d4820563e4b0, content=<a href='/topic/show?id=9205623394a' target=_blank style='color:#2F92EE;'>#案例分析#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62339, encryptionId=9205623394a, topicName=案例分析)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c30265, createdName=jiafufeng@yaho, createdTime=Sun May 23 09:08:48 CST 2021, time=2021-05-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1610692, encodeId=497916106924b, content=<a href='/topic/show?id=eb6b1145939' target=_blank style='color:#2F92EE;'>#Med#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11459, encryptionId=eb6b1145939, topicName=Med)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=552a19396740, createdName=ms3994565386320060, createdTime=Wed Sep 09 10:08:48 CST 2020, time=2020-09-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1028516, encodeId=7b4c10285163a, content=新冠肺炎,疫情何时才能消失, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=公卫新人, createdTime=Mon Sep 07 22:08:48 CST 2020, time=2020-09-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1036259, encodeId=899b10362592f, content=顶刊就是顶刊,谢谢梅斯带来这么高水平的研究报道,我们科里同事经常看梅斯,分享梅斯上的信息, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=旺医, createdTime=Mon Sep 07 22:08:48 CST 2020, time=2020-09-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=883385, encodeId=4493883385aa, content=好, beContent=null, objectType=article, channel=null, level=null, likeNumber=98, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bbc11488193, createdName=thm112988, createdTime=Mon Sep 07 19:10:53 CST 2020, time=2020-09-07, status=1, ipAttribution=)]
    2020-09-07 公卫新人

    新冠肺炎,疫情何时才能消失

    0

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    2020-09-07 旺医

    顶刊就是顶刊,谢谢梅斯带来这么高水平的研究报道,我们科里同事经常看梅斯,分享梅斯上的信息

    0

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    2020-09-07 thm112988

    0

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