RedHill的RHB-104完成了克罗恩病治疗的主要终点

2018-07-30 MedSci MedSci原创

RedHill制药今日表示，针对克罗恩病患者的实验性药物RHB-104的III期研究符合其主要终点，以及关键的次要终点。首席执行官Dror Ben-Asher表示：“我们期待与FDA讨论RHB-104的审批之路，并加快与潜在制药合作伙伴的讨论”。

RedHill制药今日表示，针对克罗恩病患者的实验性药物RHB-104的III期研究符合其主要终点，以及关键的次要终点。首席执行官Dror Ben-Asher表示：“我们期待与FDA讨论RHB-104的审批之路，并加快与潜在制药合作伙伴的讨论”。

该项III期试验将331名患有中度至重度活动性克罗恩病的患者随机接受RHB-104或安慰剂治疗。结果显示，对于主要终点，37％接受RHB-104的患者在第26周达到缓解，定义为克罗恩病活动指数（CDAI）值小于150，而安慰剂组仅为23％。此外，实验药物与安慰剂相比，在实现早期缓解方面具有显著的益处（定义为第16周的缓解），以及在第16周至第52周的持久缓解（定义为整个治疗期间的持续缓解）。RedHill补充说，在治疗52周时，RHB-104组的缓解率继续高于安慰剂，分别为27％和20％。该公司医疗总监Ira Kalfus表示：“这项研究的有力结果表明，RHB-104可能成为克罗恩病的主要治疗选择”。

原始出处：

http://www.firstwordpharma.com/node/1581701?tsid=4#axzz5MVjkDWbV

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2019-02-07 andy2100

#RedHill#

41 0
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2019-02-17 zhangj7108

#主要终点#

32 0
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2018-08-05 cscdliu

学习了，谢谢

71 0
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2018-08-01 kafei

学习了谢谢

61 0
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2018-07-31 西西er

期待新药早点上市

1 0
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2018-07-31 太阳系小猪

很赞！学习了！

72 0
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2018-07-31 飛歌

厉害了我的妹

72 0
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2018-07-30 happsf

学习

24 0
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2018-07-30 王秀

学习了，涨知识了！

26 0

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