Diabetologia:与非糖尿病患者相比,年龄、性别和种族在体重、血压、糖化血红蛋白和血脂水平上的差异?

2020-08-31 MedSci原创 MedSci原创

这项工作的目的是确定体重模式以及血糖、血压和血脂在糖尿病诊断中如何随年龄、性别和种族而变化。

这项工作的目的是确定体重模式以及血糖、血压和血脂在糖尿病诊断中如何随年龄、性别和种族而变化。

根据英国临床实践研究数据,研究人员确定了1998-2015年确诊的2型糖尿病患者(n = 187,601),并按性别和种族将他们的体重、糖化血红蛋白、血压和血脂水平与年龄相仿的非糖尿病患者(n = 906,182)进行了比较。

研究结果表明,诊断年龄越小,2型糖尿病患者与非2型糖尿病患者之间的校正平均体重差异(95% CI)越大:20-39岁时为18.7 (18.3,19.1)kg, 80岁时为5.3 (5.0,5.5)kg。白人女性的体重差异最大,与南亚人和黑人相比,白人的差异约为前者的两倍。尽管绝对值较低,但糖尿病发病年龄越小,血压差异也越大:20-39岁时血压为7 (6,7)mmHg,年龄≥80岁时血压为- 0.5(−0.9,−0.2)mmHg。白人的血压差异最大,尤其是女性。三酰基甘油水平的差异在年轻男性中最大。最后,糖化血红蛋白水平在较年轻的糖尿病发病人群中也较高,尤其是黑人。

在诊断为2型糖尿病时,与没有糖尿病的人相比,年轻人与老年人、女性与男性、白人与南亚人和黑人的体重和血压差异更大。这些差异是观察到的,尽管南亚人和黑人倾向于早10年发展糖尿病,或相似或更严重的血糖异常。这些显著的模式可能会对管理预防产生影响。

原始出处:

Alison K. Wright, Paul Welsh,Age-, sex- and ethnicity-related differences in body weight, blood pressure, HbA1c and lipid levels at the diagnosis of type 2 diabetes relative to people without diabetes

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    2020-09-01 14818eb4m67暂无昵称

    学习

    0

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    2020-08-31 misszhang

    谢谢MedSci提供最新的资讯

    0

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