Sleep Med:睡眠呼吸暂停与CABG患者室性心律失常风险

2018-02-12 国际循环编辑部 国际循环

一项最新研究表明,睡眠呼吸障碍(SDB)可能与冠状动脉旁路移植术(CABG)前心肌复极化异常具有相关性,可增加CABG患者室性心律失常的发生风险。

一项最新研究表明,睡眠呼吸障碍(SDB)可能与冠状动脉旁路移植术(CABG)前心肌复极化异常具有相关性,可增加CABG患者室性心律失常的发生风险。

研究者德国雷根斯堡大学医学中心的Christoph Fisser等共计入选2014~2015年其中心行CABG治疗的100例既往无睡眠呼吸暂停病史的患者,通过CABG前一夜的多导图评估呼吸暂停,通过12导联心电图所示的T-peak-to-end(TpTe)、QTc间期及TpTe/QT评估心脏复极化。受试患者平均年龄为68岁,平均BMI为28.7 kg/m2,男性占84%;共计37例患者存在SDB(呼吸暂停低通气指数≥15),中枢性睡眠呼吸暂停(CSA)和阻塞性睡眠呼吸暂停(OSA)患者分别有14例和23例。

进一步分析发现,患者CABG术前不论存在哪种类型睡眠呼吸暂停,与不伴有SDB者相比,其平均TpTe间隔均明显延长,平均TpTe/QT比值显著增加。但是,术前QTc间期则仅在OSA患者中所有延长。多因素分析显示,校正年龄、BMI、NT-proBNP增高及心力衰竭等已知心律失常危险因素后,SBD与心脏复极化异常具有独立相关性。但是,CABG术后两组患者的心脏复极化参数无差异。

克利夫兰诊所的Daniel Cantillon认为,该研究存在一定的局限性,但提示SDB可增加CABG术后室性室性心律失常风险。因此,临床实践中对于伴有SDB的CABG患者,应在术后恢复期给予重点关注。

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    2018-02-14 三生有幸9135

    学习一下谢谢分享

    0

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    2018-02-13 飘飘爱

    很好

    0

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    2018-02-12 有备才能无患

    一项最新研究表明.睡眠呼吸障碍(SDB)可能与冠状动脉旁路移植术(CABG)前心肌复极化异常具有相关性.可增加CABG患者室性心律失常的发生风险.

    0

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