Gastroenterology.:水下内镜下黏膜切除术可提高肠息肉的切除率

2019-08-06 MedSci MedSci原创

UEMR显著增加了10-20mm无蒂结直肠病变的R0切除率

内镜下黏膜切除术(EMR)结合黏膜下注射是切除大肠息肉的一种有效方法,但当息肉直径超过10 mm时,整体切除率降低。局部切除增加局部复发。水下EMR(UEMR)是一种有效的切除无梗结直肠息肉的技术,近日研究人员就EMR对大息肉的切除效果进行了考察。

研究在日本开展。经内镜诊断为中等大小(10~20 mm) 无蒂结直肠病变的患者随机分为接受UEMR或常规EMR(CEMR)。EUEMR手术将整个管腔浸入水中,在不注射生理盐水的情况下切除病变。研究的主要终点是各组间组织学证实为阴性切缘的整块切除(R0)率的差异。

EUEMR组R0切除率为69%,CEMR组为50%。EUEMR组整体切除率为89%,CEMR组为75% (P=0.007)。组间中位手术时间(165 vs 175秒)和不良事件患者比例(UEMR组为2.8%,CEMR组为2.0%)无显著性差异(P>0.05)。

研究认为,UEMR显著增加了10-20mm无蒂结直肠病变的R0切除率。

原始出处:


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    2019-08-08 snowpeakxu

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