J Am Coll Surg:种族及环境因素影响下肢动脉阻塞的截肢率

2018-02-26 国际循环编辑部 国际循环

《美国外科医学杂志》1月19日在线发表的一项有关纽约州数据的最新研究显示,腿部动脉严重阻塞的患者有时可通过手术治疗实现血运重建,否则需截肢。截肢风险会受种族差异影响。

《美国外科医学杂志》1月19日在线发表的一项有关纽约州数据的最新研究显示,腿部动脉严重阻塞的患者有时可通过手术治疗实现血运重建,否则需截肢。截肢风险会受种族差异影响。

研究者哈佛大学医学院的Sahael Stapleton等对1999~2014年间纽约州数据库中215 000余例因重度肢体缺血接受治疗的患者进行分析。结果发现,受试患者的截肢率为38%。其中黑人及白种人患者的截肢率分别为43%和27%;与白种人相比,黑人患者的截肢风险可增加46%。进一步分析发现,在手术量较大的医院及血管外科手术量较大或黑人患者数量较少的医生中,上述种族差异更显著。研究者分析认为,早期诊疗及患者术后自我管理能力差异可能是导致上述种族差异的重要原因。

Widener大学的Kristin Lefebvre评论认为,该研究存在仅采用纽约州的数据以及种族偏倚难以与其他变量差异进行分割等局限性,却增加了人们对于下肢动脉阻塞截肢率种族差异的认识。西北大学Feinberg医学院的Joe Feinglass评论认为,尽管种族差异会影响下肢动脉阻塞患者的截肢风险,但可能不同种族患者就诊医院及医疗服务体系差异才是更重要的因素;该研究中不同种族患者截肢率的差异可能反映决定健康的潜在社会因素的差异。

原始出处:
Sahael M. Stapleton, et al. Variation in Amputation Risk for Black Patients: Uncovering Potential Sources of Bias and Opportunities for Intervention. Journal of the American College of Surgeons. Jan 19, 2018.

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    2018-11-13 tomyang96
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    2018-11-30 waiwai3030
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