Retina:视网膜剥离手术引起内界膜剥离后与Alport综合征相似

2018-09-23 MedSci MedSci原创

名古屋大学医学研究科眼科的Fukukita H近日在Retina上发表了一篇有趣的文章。视网膜的最内层基底膜,也就是内界膜(ILM),有时会在玻璃体手术中被剥离。他们探究了ILM丢失后对视网膜的影响。

名古屋大学医学研究科眼科的Fukukita H近日在Retina上发表了一篇有趣的文章。视网膜的最内层基底膜,也就是内界膜(ILM),有时会在玻璃体手术中被剥离。他们探究了ILM丢失后对视网膜的影响。

他们使用光学相干断层扫描技术,对26例玻璃体切除术后视网膜脱离患者进行回顾性研究,观察26只眼的视网膜变化,其中11只ILM被剥离,15只眼睛中ILM没有被剥离。此外,他们研究了三名患有Alport综合征患者的六只眼,其中ILM是遗传性受损。

结果他们观察到中央凹向视盘的凹陷显着地向内部视网膜位移,鼻区内视网膜增厚(91.9±24.3μm,210.3±31.4μm; P = 0.048),颞区视网膜内层变薄(174.3±18.3μm,142.2±23.6μm; P <0.001)。同时出现黄斑中心凹增厚,ILM未剥离为217.0±39.4μm,ILM剥离的眼睛为302.0±86.2μm,P = 0.006。Alport综合征的眼睛表现出类似的发现。

因此,他们认为,内界膜出现功能障碍后,在先天性和后天性条件下都可以引起黄斑内部视网膜的特征性变化。

原文出处:

Fukukita, H., et al., INNER MACULAR CHANGES AFTER VITRECTOMY WITH INTERNAL LIMITING MEMBRANE PEELING FOR RHEGMATOGENOUS RETINAL DETACHMENT: Similarity With Alport Syndrome. Retina, 2018.

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    2019-05-30 jiekemin
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    2019-04-01 ysjykql
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    2019-06-10 仁医06
  5. [GetPortalCommentsPageByObjectIdResponse(id=2036003, encodeId=13952036003c7, content=<a href='/topic/show?id=01482345fc' target=_blank style='color:#2F92EE;'>#ALP#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2345, encryptionId=01482345fc, topicName=ALP)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5c82369, createdName=jiekemin, createdTime=Thu May 30 04:17:00 CST 2019, time=2019-05-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1913892, encodeId=7b7a191389287, content=<a href='/topic/show?id=4684153e41f' target=_blank style='color:#2F92EE;'>#RET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=15374, encryptionId=4684153e41f, topicName=RET)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=96d4340, createdName=ysjykql, createdTime=Mon Apr 01 22:17:00 CST 2019, time=2019-04-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1793311, encodeId=24de1e9331198, content=<a href='/topic/show?id=5400153e639' target=_blank style='color:#2F92EE;'>#Retina#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=15376, encryptionId=5400153e639, topicName=Retina)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0d342500153, createdName=12498bf3m25暂无昵称, createdTime=Thu May 02 12:17:00 CST 2019, time=2019-05-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1954069, encodeId=794c1954069d8, content=<a href='/topic/show?id=c9a6235842' target=_blank style='color:#2F92EE;'>#Alport#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2358, encryptionId=c9a6235842, topicName=Alport)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=55683, createdName=仁医06, createdTime=Mon Jun 10 05:17:00 CST 2019, time=2019-06-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1270112, encodeId=1c3a12e01126f, content=<a href='/topic/show?id=979690e33bd' target=_blank style='color:#2F92EE;'>#视网膜#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=90733, encryptionId=979690e33bd, topicName=视网膜)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=742793, createdName=zutt, createdTime=Tue Sep 25 04:17:00 CST 2018, time=2018-09-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1431332, encodeId=2743143133206, content=<a href='/topic/show?id=f9b9e9124a8' target=_blank style='color:#2F92EE;'>#综合征#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79124, encryptionId=f9b9e9124a8, topicName=综合征)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=zhouqu_8, createdTime=Tue Sep 25 04:17:00 CST 2018, time=2018-09-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1458427, encodeId=7538145842e59, content=<a href='/topic/show?id=782423592a' target=_blank style='color:#2F92EE;'>#Alport综合征#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2359, encryptionId=782423592a, topicName=Alport综合征)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b6846069053, createdName=lancelotzzl, createdTime=Tue Sep 25 04:17:00 CST 2018, time=2018-09-25, status=1, ipAttribution=)]
    2018-09-25 zutt
  6. [GetPortalCommentsPageByObjectIdResponse(id=2036003, encodeId=13952036003c7, content=<a href='/topic/show?id=01482345fc' target=_blank style='color:#2F92EE;'>#ALP#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2345, encryptionId=01482345fc, topicName=ALP)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5c82369, createdName=jiekemin, createdTime=Thu May 30 04:17:00 CST 2019, time=2019-05-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1913892, encodeId=7b7a191389287, content=<a href='/topic/show?id=4684153e41f' target=_blank style='color:#2F92EE;'>#RET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=15374, encryptionId=4684153e41f, topicName=RET)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=96d4340, createdName=ysjykql, createdTime=Mon Apr 01 22:17:00 CST 2019, time=2019-04-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1793311, encodeId=24de1e9331198, content=<a href='/topic/show?id=5400153e639' target=_blank style='color:#2F92EE;'>#Retina#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=15376, encryptionId=5400153e639, topicName=Retina)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0d342500153, createdName=12498bf3m25暂无昵称, createdTime=Thu May 02 12:17:00 CST 2019, time=2019-05-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1954069, encodeId=794c1954069d8, content=<a href='/topic/show?id=c9a6235842' target=_blank style='color:#2F92EE;'>#Alport#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2358, encryptionId=c9a6235842, topicName=Alport)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=55683, createdName=仁医06, createdTime=Mon Jun 10 05:17:00 CST 2019, time=2019-06-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1270112, encodeId=1c3a12e01126f, content=<a href='/topic/show?id=979690e33bd' target=_blank style='color:#2F92EE;'>#视网膜#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=90733, encryptionId=979690e33bd, topicName=视网膜)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=742793, createdName=zutt, createdTime=Tue Sep 25 04:17:00 CST 2018, time=2018-09-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1431332, encodeId=2743143133206, content=<a href='/topic/show?id=f9b9e9124a8' target=_blank style='color:#2F92EE;'>#综合征#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79124, encryptionId=f9b9e9124a8, topicName=综合征)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=zhouqu_8, createdTime=Tue Sep 25 04:17:00 CST 2018, time=2018-09-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1458427, encodeId=7538145842e59, content=<a href='/topic/show?id=782423592a' target=_blank style='color:#2F92EE;'>#Alport综合征#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2359, encryptionId=782423592a, topicName=Alport综合征)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b6846069053, createdName=lancelotzzl, createdTime=Tue Sep 25 04:17:00 CST 2018, time=2018-09-25, status=1, ipAttribution=)]
    2018-09-25 zhouqu_8
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