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Kadimastem报告其针对渐冻症的干细胞疗法阳性结果

2020-01-03 不详 MedSci原创

Kadimastem渐冻症干细胞疗法
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据Globes报道，Kadimastem公司宣布了其正在开发的干细胞疗法AstroRx用于肌萎缩性侧索硬化症（ALS）的I / IIa期细胞替代试验中，用该药治疗的第一组患者的结果。

据Globes报道，Kadimastem公司宣布了其正在开发的干细胞疗法AstroRx用于肌萎缩性侧索硬化症（ALS）的I / IIa期细胞替代试验中，用该药治疗的第一组患者的结果。

六个月的监测后，未见严重副作用，也未发现毒性限制治疗剂量。

该公司先前报告说，经过三个月的治疗，ALS患者的运动状况评分改善了0.26分，而在开始治疗之前的三个月中，对照患者的病情却恶化了0.87分。

Kadimastem在最新结果中表示，患者的病情已恢复。五到六个月后，患者再次恶化，其恶化速度与未经治疗的预期相同。

将有另外两组患者参加该试验，并且比前五位患者接受的剂量要高出两剂。该公司还考虑改变试验方案，以最终包括四个小组，其中一个小组每隔两至三个月接受两次注射。

根据该公司的网站，Kadimastem正在开发干细胞疗法AstroRx，由人类胚胎干细胞衍生的星形胶质细胞组成的，用于治疗ALS和其他神经退行性疾病。

原始出处：


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    2020-02-10 12498cb5m20暂无昵称

    #阳性结果#

    0

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    2020-04-15 ms24272190615788285182

    #AST#

    0

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    2020-11-24 dongjia2010

    #Kadimastem#

    0

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    2020-01-06 独孤立克

    干细胞是热点，但是进入临床仍然需要时间和临床疗效验证哦

    0

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    2020-01-05 xjy02

    #渐冻症#

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1642058, encodeId=9126164205874, content=<a href='/topic/show?id=679b9e514c8' target=_blank style='color:#2F92EE;'>#阳性结果#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97514, encryptionId=679b9e514c8, topicName=阳性结果)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=28fb22837833, createdName=12498cb5m20暂无昵称, createdTime=Mon Feb 10 16:03:00 CST 2020, time=2020-02-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1712260, encodeId=b7b91e1226073, content=<a href='/topic/show?id=9a1c289680' target=_blank style='color:#2F92EE;'>#AST#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2896, encryptionId=9a1c289680, topicName=AST)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8b9831894722, createdName=ms24272190615788285182, createdTime=Wed Apr 15 05:03:00 CST 2020, time=2020-04-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2050127, encodeId=2f2a205012ed5, content=<a href='/topic/show?id=5e74104006f' target=_blank style='color:#2F92EE;'>#Kadimastem#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10400, encryptionId=5e74104006f, topicName=Kadimastem)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3547346, createdName=dongjia2010, createdTime=Tue Nov 24 13:03:00 CST 2020, time=2020-11-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1025381, encodeId=f1821025381e5, content=干细胞是热点，但是进入临床仍然需要时间和临床疗效验证哦, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=独孤立克, createdTime=Mon Jan 06 12:03:00 CST 2020, time=2020-01-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1269701, encodeId=b1241269e0141, content=<a href='/topic/show?id=5e106628237' target=_blank style='color:#2F92EE;'>#渐冻症#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=66282, encryptionId=5e106628237, topicName=渐冻症)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d59291, createdName=xjy02, createdTime=Sun Jan 05 03:03:00 CST 2020, time=2020-01-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1314489, encodeId=fbd213144890d, content=<a href='/topic/show?id=4c6348e80a9' target=_blank style='color:#2F92EE;'>#干细胞疗法#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=48780, encryptionId=4c6348e80a9, topicName=干细胞疗法)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5319428, createdName=jjjiang0199, createdTime=Sun Jan 05 03:03:00 CST 2020, time=2020-01-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1482285, encodeId=3ff0148228532, content=<a href='/topic/show?id=8cc416e78f3' target=_blank style='color:#2F92EE;'>#STEM#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=16778, encryptionId=8cc416e78f3, topicName=STEM)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d1067833268, createdName=12498bb3m92(暂无昵称), createdTime=Sun Jan 05 03:03:00 CST 2020, time=2020-01-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=377781, encodeId=bf903e778141, content=期待突破, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3xjZ9qh3bhXrJtUlmycKGfQKPuADVZQsdNAQj5IrHHlzbGsDwScictBgogYRk8KhicpgEKwTEfOHgqw/0, createdBy=bc931611963, createdName=jin321, createdTime=Sat Jan 04 21:05:52 CST 2020, time=2020-01-04, status=1, ipAttribution=)]
    2020-01-05 jjjiang0199

    #干细胞疗法#

    0

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    2020-01-05 12498bb3m92(暂无昵称)

    #STEM#

    0

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    2020-01-04 jin321

    期待突破

    0