Eur Heart J:妊娠相关的动脉夹层

2020-08-01 MedSci原创 MedSci原创

5.5/100000的住院孕妇或产后妇女发生动脉夹层,最常见于产后期,并与高死亡风险相关。冠状动脉夹层最为常见。妊娠相关的夹层与传统的危险因素以及特定的妊娠状况有关。

妊娠是动脉夹层已知的危险因素,动脉夹层可使围产期发病率和死亡率显著增加。但是,对于与妊娠相关的动脉夹层的危险因素、时机、分布和结局知之甚少。

近日,血管领域权威杂志Eur Heart J上发表了一篇研究文章,研究人员将2010年至2015年之间所有≥12岁的因妊娠和/或分娩而住院的妇女纳入了全国再入院数据库。该研究的主要结局是在妊娠、分娩或产后期间(分娩后42天)出现的任何夹层。该研究的次要结局包括夹层时机、夹层位置和院内死亡率。

在18151897名孕妇中,有993名(0.005%)患者被诊断出与妊娠有关的夹层。危险因素包括老年(32.8 vs. 28.0岁)、多胎妊娠(3.6% vs. 1.9%)、妊娠糖尿病(14.3% vs. 0.2%)、妊娠高血压(6.0% vs. 0.6%)和先兆子痫/子痫(2.7% vs. 0.4%)以及传统的心血管危险因素。在993例夹层患者中,有150例(15.1%)在产前发生夹层,232例(23.4%)在分娩时被诊断,611例(61.5%)在产后期间被诊断。最常见的夹层部位是冠状动脉(38.2%)、椎动脉(22.9%)、主动脉(19.8%)和颈动脉(19.5%)。夹层孕妇的院内死亡率为3.7%,而无夹层孕妇<0.001%。

由此可见,5.5/100000的住院孕妇或产后妇女发生动脉夹层,最常见于产后期,并与高死亡风险相关。冠状动脉夹层最为常见。妊娠相关的夹层与传统的危险因素以及特定的妊娠状况有关。
 
原始出处:
 
Sebastian E Beyer.et al.Pregnancy-associated arterial dissections: a nationwide cohort study.Eur Heart J.2020.https://doi.org/10.1093/eurheartj/ehaa497

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    2020-08-03 zhaojie88
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    2020-08-03 slcumt
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    2020-08-02 1240394fm61暂无昵称

    孕期血管检查是不是也是有必要的。

    0

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    2020-08-02 1240394fm61暂无昵称

    动脉夹层,怀孕风险太高

    0

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    2020-08-01 Arvin0001
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    2020-08-01 ms5000000545858632

    学习,学习

    0

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