Sci Rep:Bio-Gide膜与钛网结合可有效修复种植体周围牙槽骨缺损

2018-11-18 MedSci MedSci原创

为了指导选择屏障膜治疗种植体周围牙槽骨缺损,我们评估了钛(Ti)网或Bio-Gide膜,单独或组合引导骨再生(GBR)以修复Beagle犬的牙槽骨缺损的效果。拔除三个小猎兔犬的下颌臼齿和第一臼齿后六个月,植入种植体,并分别覆盖有下列膜:A组:种植体+ BIO-Oss + Ti基网,B组:种植体+BIO-Oss + Bio-Gide和C组:植入物+ Bio-Oss + Ti-mesh + Bio-G

为了指导选择屏障膜治疗种植体周围牙槽骨缺损,我们评估了钛(Ti)网或Bio-Gide膜,单独或组合引导骨再生(GBR)以修复Beagle犬的牙槽骨缺损的效果。

拔除三个小猎兔犬的下颌臼齿和第一臼齿后六个月,植入种植体,并分别覆盖有下列膜:A组:种植体+ BIO-Oss + Ti基网,B组:种植体+BIO-Oss + Bio-Gide和C组:植入物+ Bio-Oss + Ti-mesh + Bio-Gide。

在6个月时,micro-CT显示C组的骨量/总体积(BV / TV),小梁数(Tb.N)和小梁厚度(Tb.Th)明显高于其他两组,而小梁分离(Tb.Sp)显著降低,表明骨再生得到改善。C组中三种荧光追踪染料的条带之间的距离明显更大,表明新骨的沉积更快。Bio-Oss颗粒与新沉积的骨骼完美结合,C组骨厚度明显增大。

综上所述,这些研究结果表明,与单独使用钛网或Bio-Gide相比,Bio-Gide膜与钛网结合可有效修复种植体周围牙槽骨缺损,实现骨再生增强,为临床种植手术提供了一种新的治疗理念。

原始出处:

HuiPing Li, JiSi Zheng, et al., Experiment of GBR for repair of peri-implant alveolar defects in beagle dogs. Sci Rep. 2018; 8: 16532.


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    2018-12-19 huangdf
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    2019-08-31 sunylz
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    2019-06-17 30397613
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    2019-03-28 mei540
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    2018-11-20 lfcmxl