J Periodontol:牙周炎与血脂水平关系的研究

2018-02-23 MedSci MedSci原创

高脂血症是心血管疾病的风险因素。已知全身性疾病如心血管疾病和牙周病之间有共同的生物机制。这项研究的目的是研究血脂和牙周炎之间的关系。

高脂血症是心血管疾病的风险因素。已知全身性疾病如心血管疾病和牙周病之间有共同的生物机制。这项研究的目的是研究血脂和牙周炎之间的关系。

该研究纳入6,905名20岁以上的韩国成年人。在2010年和2012年使用社区牙周指数系统的第五次韩国国家健康和营养调查中,缺乏血脂数据的患者和缺乏牙周炎检查结果的患者以及诊断糖尿病高血压和高脂血症的患者被排除在外。所有分析涉及复杂的样本设计。使用根据协变量调整的多重逻辑回归分析评估关联性。

结果发现,高密度脂蛋白(HDL)水平低的女性患牙周炎的风险增高(优势比(OR)[95%置信区间(CI)]:最低组为1.65 [1.03-2.66])高于高HDL水平。低密度脂蛋白(LDL)水平高的女性患病的风险较高(OR为95%CI:2.38 [1.01-5.60]为最高组)。疾病风险与HDL和LDL水平之间存在显着的剂量 - 反应关系(P趋势分别为0.001和0.04)。绝经前和绝经后妇女的风险之间没有显着差异。男性在血脂水平和牙周炎之间没有显示任何显着关联。

结论:女性牙周炎与低HDL和高LDL之间存在显着相关性。

原始出处:

Aejung Im, et al. Association between periodontitis and blood lipid levels in a Korean population. Journal of Periodontology. 2018 January. doi:10.1902/jop.2017.170111

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    2019-01-15 feather89
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    2018-02-24 lou.minghong

    生物机制是什么?

    0

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    2018-02-23 天地飞扬

    了解一下.谢谢分享!

    0

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