Nat Med:中国万州是如何有效控制SARS-CoV-2病毒传播 ?

2020-12-01 haibei MedSci原创

万州是中国重庆的一个拥有174万人口的城市,与湖北省西部接壤。作为湖北省通往中国西南地区的门户,万州迅速受到COVID-19疫情的影响,其震中是武汉。

万州是中国重庆的一个拥有174万人口的城市,与湖北省西部接壤。作为湖北省通往中国西南地区的门户,万州迅速受到COVID-19疫情的影响,其震中是武汉。

2020年1月下旬春节假期期间,约有2万人从湖北省返回万州。随着2020年1月23日武汉及周边地区的封锁,万州也成为流行病学调查的封闭环境。这些情况为更好地了解COVID-19的致病菌--严重急性呼吸道综合征冠状病毒2(SARS-CoV-2)1的传播动态和危险因素提供了机会。

中国22个省约有47个城市的人口规模与万州相似(150万至250万),并采取了同样的遏制措施来应对COVID-19疫情。此外,万州的人口规模与欧洲和美国的大中型城市相当。这些特点使万州成为受COVID-19疫情严重影响的国家和城市的研究人员和政策制定者更好地了解SARS-CoV-2感染的传播动态和风险因素,以及控制措施的有效性的合适例子。

最近,研究人员在Nature Medicine发文,评估了中国万州2019年冠状病毒病(COVID-19)控制措施的有效性。对整个万州COVID-19疫情期间183例COVID-19确诊病例及其五代传播的密切接触者的流行病学数据进行了分析,这些病例均为重症急性呼吸综合征冠状病毒2型。有症状和无症状的病例分别约占67.2%和32.8%。无症状和症状前传播占记录传播总数的75.9%。G1-G2传播的繁殖数为1.64(95%置信区间:1.16-2.40),随着严格控制措施的实施,后几代的繁殖数下降到0.31-0.39。

感染者感染后5 d内接触、频繁接触和接触时间≥8 h的感染风险大幅提高。通过社会疏散、广泛的接触者追踪、大规模检测和严格的密切接触者隔离等措施,切断传播链,COVID-19在万州的传播得到有效控制。

 

 

原始出处:

Qiuling Shi et al. Effective control of SARS-CoV-2 transmission in Wanzhou, China. Nature Medicine (2020). 

 

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (5)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1937972, encodeId=66b7193e97231, content=<a href='/topic/show?id=02de15902d3' target=_blank style='color:#2F92EE;'>#SARS-CoV#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=15902, encryptionId=02de15902d3, topicName=SARS-CoV)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6ab940, createdName=hukaixun, createdTime=Tue Aug 31 06:25:47 CST 2021, time=2021-08-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1884830, encodeId=d5eb18848308b, content=<a href='/topic/show?id=3b2112532d8' target=_blank style='color:#2F92EE;'>#Nat#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12532, encryptionId=3b2112532d8, topicName=Nat)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2e6f107, createdName=liye789132251, createdTime=Sun Mar 07 10:25:47 CST 2021, time=2021-03-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1321238, encodeId=3c3c132123820, content=<a href='/topic/show?id=ac0d159007f' target=_blank style='color:#2F92EE;'>#SARS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=15900, encryptionId=ac0d159007f, topicName=SARS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8306486, createdName=小刀医生, createdTime=Thu Dec 03 05:25:47 CST 2020, time=2020-12-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1610809, encodeId=903516108094d, content=<a href='/topic/show?id=eb6b1145939' target=_blank style='color:#2F92EE;'>#Med#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11459, encryptionId=eb6b1145939, topicName=Med)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=552a19396740, createdName=ms3994565386320060, createdTime=Thu Dec 03 05:25:47 CST 2020, time=2020-12-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=903934, encodeId=4ada903934e0, content=厉害了!通过社会疏散、广泛的接触者追踪、大规模检测和严格的密切接触者隔离等措施,切断传播链,COVID-19在万州的传播得到有效控制!中国速度!, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201120/5008534db22c474a844fbd107ff83af2/d3e20fc133b542208ff15e7f2b575329.jpg, createdBy=c7015311102, createdName=Jessie Zhang, createdTime=Tue Dec 01 17:34:34 CST 2020, time=2020-12-01, status=1, ipAttribution=)]
    2021-08-31 hukaixun
  2. [GetPortalCommentsPageByObjectIdResponse(id=1937972, encodeId=66b7193e97231, content=<a href='/topic/show?id=02de15902d3' target=_blank style='color:#2F92EE;'>#SARS-CoV#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=15902, encryptionId=02de15902d3, topicName=SARS-CoV)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6ab940, createdName=hukaixun, createdTime=Tue Aug 31 06:25:47 CST 2021, time=2021-08-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1884830, encodeId=d5eb18848308b, content=<a href='/topic/show?id=3b2112532d8' target=_blank style='color:#2F92EE;'>#Nat#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12532, encryptionId=3b2112532d8, topicName=Nat)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2e6f107, createdName=liye789132251, createdTime=Sun Mar 07 10:25:47 CST 2021, time=2021-03-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1321238, encodeId=3c3c132123820, content=<a href='/topic/show?id=ac0d159007f' target=_blank style='color:#2F92EE;'>#SARS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=15900, encryptionId=ac0d159007f, topicName=SARS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8306486, createdName=小刀医生, createdTime=Thu Dec 03 05:25:47 CST 2020, time=2020-12-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1610809, encodeId=903516108094d, content=<a href='/topic/show?id=eb6b1145939' target=_blank style='color:#2F92EE;'>#Med#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11459, encryptionId=eb6b1145939, topicName=Med)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=552a19396740, createdName=ms3994565386320060, createdTime=Thu Dec 03 05:25:47 CST 2020, time=2020-12-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=903934, encodeId=4ada903934e0, content=厉害了!通过社会疏散、广泛的接触者追踪、大规模检测和严格的密切接触者隔离等措施,切断传播链,COVID-19在万州的传播得到有效控制!中国速度!, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201120/5008534db22c474a844fbd107ff83af2/d3e20fc133b542208ff15e7f2b575329.jpg, createdBy=c7015311102, createdName=Jessie Zhang, createdTime=Tue Dec 01 17:34:34 CST 2020, time=2020-12-01, status=1, ipAttribution=)]
    2021-03-07 liye789132251
  3. [GetPortalCommentsPageByObjectIdResponse(id=1937972, encodeId=66b7193e97231, content=<a href='/topic/show?id=02de15902d3' target=_blank style='color:#2F92EE;'>#SARS-CoV#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=15902, encryptionId=02de15902d3, topicName=SARS-CoV)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6ab940, createdName=hukaixun, createdTime=Tue Aug 31 06:25:47 CST 2021, time=2021-08-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1884830, encodeId=d5eb18848308b, content=<a href='/topic/show?id=3b2112532d8' target=_blank style='color:#2F92EE;'>#Nat#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12532, encryptionId=3b2112532d8, topicName=Nat)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2e6f107, createdName=liye789132251, createdTime=Sun Mar 07 10:25:47 CST 2021, time=2021-03-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1321238, encodeId=3c3c132123820, content=<a href='/topic/show?id=ac0d159007f' target=_blank style='color:#2F92EE;'>#SARS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=15900, encryptionId=ac0d159007f, topicName=SARS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8306486, createdName=小刀医生, createdTime=Thu Dec 03 05:25:47 CST 2020, time=2020-12-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1610809, encodeId=903516108094d, content=<a href='/topic/show?id=eb6b1145939' target=_blank style='color:#2F92EE;'>#Med#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11459, encryptionId=eb6b1145939, topicName=Med)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=552a19396740, createdName=ms3994565386320060, createdTime=Thu Dec 03 05:25:47 CST 2020, time=2020-12-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=903934, encodeId=4ada903934e0, content=厉害了!通过社会疏散、广泛的接触者追踪、大规模检测和严格的密切接触者隔离等措施,切断传播链,COVID-19在万州的传播得到有效控制!中国速度!, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201120/5008534db22c474a844fbd107ff83af2/d3e20fc133b542208ff15e7f2b575329.jpg, createdBy=c7015311102, createdName=Jessie Zhang, createdTime=Tue Dec 01 17:34:34 CST 2020, time=2020-12-01, status=1, ipAttribution=)]
    2020-12-03 小刀医生
  4. [GetPortalCommentsPageByObjectIdResponse(id=1937972, encodeId=66b7193e97231, content=<a href='/topic/show?id=02de15902d3' target=_blank style='color:#2F92EE;'>#SARS-CoV#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=15902, encryptionId=02de15902d3, topicName=SARS-CoV)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6ab940, createdName=hukaixun, createdTime=Tue Aug 31 06:25:47 CST 2021, time=2021-08-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1884830, encodeId=d5eb18848308b, content=<a href='/topic/show?id=3b2112532d8' target=_blank style='color:#2F92EE;'>#Nat#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12532, encryptionId=3b2112532d8, topicName=Nat)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2e6f107, createdName=liye789132251, createdTime=Sun Mar 07 10:25:47 CST 2021, time=2021-03-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1321238, encodeId=3c3c132123820, content=<a href='/topic/show?id=ac0d159007f' target=_blank style='color:#2F92EE;'>#SARS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=15900, encryptionId=ac0d159007f, topicName=SARS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8306486, createdName=小刀医生, createdTime=Thu Dec 03 05:25:47 CST 2020, time=2020-12-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1610809, encodeId=903516108094d, content=<a href='/topic/show?id=eb6b1145939' target=_blank style='color:#2F92EE;'>#Med#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11459, encryptionId=eb6b1145939, topicName=Med)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=552a19396740, createdName=ms3994565386320060, createdTime=Thu Dec 03 05:25:47 CST 2020, time=2020-12-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=903934, encodeId=4ada903934e0, content=厉害了!通过社会疏散、广泛的接触者追踪、大规模检测和严格的密切接触者隔离等措施,切断传播链,COVID-19在万州的传播得到有效控制!中国速度!, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201120/5008534db22c474a844fbd107ff83af2/d3e20fc133b542208ff15e7f2b575329.jpg, createdBy=c7015311102, createdName=Jessie Zhang, createdTime=Tue Dec 01 17:34:34 CST 2020, time=2020-12-01, status=1, ipAttribution=)]
  5. [GetPortalCommentsPageByObjectIdResponse(id=1937972, encodeId=66b7193e97231, content=<a href='/topic/show?id=02de15902d3' target=_blank style='color:#2F92EE;'>#SARS-CoV#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=15902, encryptionId=02de15902d3, topicName=SARS-CoV)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6ab940, createdName=hukaixun, createdTime=Tue Aug 31 06:25:47 CST 2021, time=2021-08-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1884830, encodeId=d5eb18848308b, content=<a href='/topic/show?id=3b2112532d8' target=_blank style='color:#2F92EE;'>#Nat#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12532, encryptionId=3b2112532d8, topicName=Nat)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2e6f107, createdName=liye789132251, createdTime=Sun Mar 07 10:25:47 CST 2021, time=2021-03-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1321238, encodeId=3c3c132123820, content=<a href='/topic/show?id=ac0d159007f' target=_blank style='color:#2F92EE;'>#SARS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=15900, encryptionId=ac0d159007f, topicName=SARS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8306486, createdName=小刀医生, createdTime=Thu Dec 03 05:25:47 CST 2020, time=2020-12-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1610809, encodeId=903516108094d, content=<a href='/topic/show?id=eb6b1145939' target=_blank style='color:#2F92EE;'>#Med#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11459, encryptionId=eb6b1145939, topicName=Med)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=552a19396740, createdName=ms3994565386320060, createdTime=Thu Dec 03 05:25:47 CST 2020, time=2020-12-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=903934, encodeId=4ada903934e0, content=厉害了!通过社会疏散、广泛的接触者追踪、大规模检测和严格的密切接触者隔离等措施,切断传播链,COVID-19在万州的传播得到有效控制!中国速度!, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201120/5008534db22c474a844fbd107ff83af2/d3e20fc133b542208ff15e7f2b575329.jpg, createdBy=c7015311102, createdName=Jessie Zhang, createdTime=Tue Dec 01 17:34:34 CST 2020, time=2020-12-01, status=1, ipAttribution=)]
    2020-12-01 Jessie Zhang

    厉害了!通过社会疏散、广泛的接触者追踪、大规模检测和严格的密切接触者隔离等措施,切断传播链,COVID-19在万州的传播得到有效控制!中国速度!

    0

相关资讯

Nat Commun:你是什么血型?血型会影响新冠感染、插管和死亡几率

新型冠状病毒病(COVID-19,由SARS-CoV-2病毒引起)已经在全球范围内迅速蔓延,截至2020年8月17日,该疾病已在全球范围内造成超过2110万例确诊感染,超过76.1万人死亡。在美国国内

Nat Commun:武汉市解封后,近千万居民核酸筛查结果怎么样?

我国研究人员也在Nature Communications杂志发文,报告了此次全市核酸筛查的组织过程、采用的详细技术方法和结果。

NATURE:新冠的年龄特异性死亡和免疫模式

最近,研究人员在Nature杂志发文,其使用来自45个国家的特定年龄的COVID-19死亡数据和22个血清流行率研究的结果,来调查多个国家的感染和死亡模式的一致性。

Nat Commun:北京市COVID-19病例基因组监测情况

研究人员根据代表性的高频单核苷酸多态性(SNPs),将所有测序基因组分为7个簇。基因组比较显示,与武汉暴露组和本地传播组相比,海外输入组的基因组多样性较高,表明在全球传播过程中基因组持续进化。

Nat Commun:复旦学者统计,武汉新冠**波大流行的疾病负担和临床严重程度

症状病例、就诊、住院和死亡的比率分别估计为每10万人796(95% CI:703-977)、489(472-509)、370(358-384)和36.2(35.0-37.3)。

JNNP:冠状病毒COVID-19对长期住院的神经病人的影响

在2月底爆发的SARS-CoV-2袭击了意大利,并迅速从伦巴第蔓延到该国其他地区,死亡人数超过31000人。尽管所有地区都报告有COVID-19患者,但确诊病例数最多的是伦巴第东部省份。1多份病例报告