BMJ:法国儿童新冠肺炎患者川崎样多系统炎症综合征特征研究

2020-06-08 MedSci原创 MedSci原创

研究认为,巴黎地区儿童和青少年川崎样多系统炎症综合征的持续爆发可能与SARS-CoV-2有关。大多数患儿有胃肠道症状,川崎病休克综合征,为非洲血统

近日研究人员在法国考察了儿童新冠肺炎患者的川崎样多系统炎症综合征风险。
 
研究在巴黎一家大学医院的普通儿科开展,2020年4月27日至5月11日收治的21名川崎病患儿(年龄≤18岁),随访至2020年5月15日。研究的主要结果是临床和生物学数据,影像学和超声心动图表现、治疗和结果。通过鼻咽拭子以及血液IgG抗体进行病毒检测。
 
21名患儿平均年龄7.9,因川崎病而入院,其中12名(57%)为非洲血统。川崎病休克综合征12例(57%),心肌炎16例(76%)。17人(81%)需要重症监护支持。21例患者均在发病早期出现明显的胃肠道症状,炎症标志物含量高。19例(90%)有SARS-CoV-2感染史(8/21例RT-PCR阳性,19/21例IgG抗体阳性)。21例患者均接受静脉注射免疫球蛋白,10例(48%)同时接受皮质类固醇治疗。所有患者的临床结果均良好。住院期间有5例(24%)患者出现中度冠状动脉扩张。到2020年5月15日,在住院8天后,所有患者均出院回家。
 
研究认为,巴黎地区儿童和青少年川崎样多系统炎症综合征的持续爆发可能与SARS-CoV-2有关。大多数患儿有胃肠道症状,川崎病休克综合征,为非洲血统。
 
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    2020-10-14 gaoxiaoe
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    2020-06-10 neurowu
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    2020-06-09 lovetcm

    #川崎病#21例结果出来了

    0

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    2020-06-09 lovetcm
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    2020-06-08 公卫新人

    新冠肺炎,疫情何时才能消失

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