Stroke:口服抗凝治疗的房颤患者体重指数与临床结局的关系

2021-01-14 MedSci原创 MedSci原创

BMI升高与较低的缺血性卒中、大出血风险相关。体重过轻的患者全因死亡和综合临床结局的风险较高。房颤患者的最佳BMI应根据综合治疗方法来确定。

体重指数(BMI)对房颤患者临床结局的影响仍存在争议,尤其是在亚洲人群中。近日,血管疾病领域权威杂志Stroke上发表了一篇研究文章,研究人员旨在评估接受口服抗凝剂的治疗的亚洲房颤患者BMI与临床结局之间的相关性。

研究人员使用2015年1月至2017年12月期间的韩国国民健康保险数据库,确定了BMI信息可用的非瓣膜性房颤患者中口服抗凝剂的新使用者。研究人员根据BMI类别分析了缺血性卒中、颅内出血、胃肠道出血的住院治疗、大出血、全因死亡以及综合临床结局。

不同BMI(kg/m2)组别共纳入43173名患者:体重不足(<18.5)占3%,正常(18.5-23)占28%,超重(23-25)占24%,肥胖I级(25-30)占39%,肥胖II级(≥30)占6%。较高BMI(每增加5 kg/m2)与缺血性卒中(风险比[HR]为0.891 [95%CI为0.801–0.992])、消化道出血住院(HR为0.785 [95%CI为0.658–0.937])、大出血(HR为0.794 [95%CI为0.686-0.919])、全因死亡(HR为0.658 [95%CI为0.605-0.716])和综合临床结局(HR为0.751 [95%CI为0.706–0.799]风险较低相关,但颅内出血除外(HR为0.815 [95%CI为0.627–1.061])。体重过轻与综合临床结局风险增加相关(HR为1.398 [95%CI为1.170-1.671]),其主要原因是全因死亡风险增加。在不同BMI组别中,非维生素K拮抗剂口服抗凝剂与华法林对患者临床结局的影响相似。

由此可见,BMI升高与较低的缺血性卒中、大出血风险相关。体重过轻的患者全因死亡和综合临床结局的风险较高。房颤患者的最佳BMI应根据综合治疗方法来确定。

原始出处:

So-Ryoung Lee.et al.Body Mass Index and Clinical Outcomes in Asian Patients With Atrial Fibrillation Receiving Oral Anticoagulation.stroke.2021.https://www.ahajournals.org/doi/10.1161/STROKEAHA.120.030356

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    2021-04-23 ms1000000246718707

    非常受教

    0

  4. 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createdBy=530b30209110, createdName=日月, createdTime=Mon Nov 01 14:00:48 CST 2021, time=2021-11-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=959888, encodeId=2096959888c8, content=非常受教, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210407/eb9837bff221487cbdcd636e52d0a050/c7163dc9b9f8443e92d6eab86900476d.jpg, createdBy=5ac35477509, createdName=ms1000000246718707, createdTime=Fri Apr 23 22:03:48 CST 2021, time=2021-04-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=927080, encodeId=841f92e08000, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=95, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=87625457057, createdName=ms1000000826952833, createdTime=Thu Feb 25 12:37:23 CST 2021, time=2021-02-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1614580, encodeId=7b98161458020, content=<a href='/topic/show?id=64f95426122' target=_blank style='color:#2F92EE;'>#房颤患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=54261, encryptionId=64f95426122, topicName=房颤患者)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=937e19519012, createdName=hittouch, createdTime=Sat Jan 16 12:00:48 CST 2021, time=2021-01-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=917123, encodeId=f65f91e1238f, content=谢谢分享!<a href='/topic/show?id=974e51e2810' target=_blank style='color:#2F92EE;'>#心血管#</a><a href='/topic/show?id=737a54248f5' target=_blank style='color:#2F92EE;'>#房颤#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=162, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51728, encryptionId=974e51e2810, topicName=心血管), TopicDto(id=54248, encryptionId=737a54248f5, topicName=房颤)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210116/132afc6a1e044714a6b3389cf5203115/12b4854892844edc89f20a98098119e4.jpg, createdBy=73985436003, createdName=ms4000001286945478, createdTime=Sat Jan 16 11:46:12 CST 2021, time=2021-01-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=916898, encodeId=601d9168987a, content=学习了~, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=15e45413315, createdName=ms7000001316886289, createdTime=Fri Jan 15 14:41:53 CST 2021, time=2021-01-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=916855, encodeId=ee0e916855f3, content=口服增加可及性, beContent=null, objectType=article, channel=null, level=null, likeNumber=94, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210315/480e12f811f44bc39b347d2521d56e86/67d0e6d503124ea685205b567af3dffd.jpg, createdBy=f9435296193, createdName=Baodongxu, createdTime=Fri Jan 15 11:37:20 CST 2021, time=2021-01-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=916817, encodeId=2d8b91681eae, content=<a href='/topic/show?id=142435598f' target=_blank style='color:#2F92EE;'>#BMI#</a>BMI升高与较低的缺血性卒中、大出血风险相关。体重过轻的患者全因死亡和综合临床结局的风险较高, beContent=null, objectType=article, channel=null, level=null, likeNumber=136, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3559, encryptionId=142435598f, topicName=BMI)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200529/3611e9bb629c4e5b81fbd8ce784b06cc/128487eae357460bb98f67d86230c218.jpg, createdBy=ab235268530, createdName=神盾医疗局局长Jack, createdTime=Fri Jan 15 10:03:34 CST 2021, time=2021-01-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1031343, encodeId=94561031343dc, content=房颤,临床上碰到很多哦, beContent=null, objectType=article, channel=null, level=null, likeNumber=14, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=心介, createdTime=Fri Jan 15 00:00:48 CST 2021, time=2021-01-15, status=1, ipAttribution=)]
    2021-02-25 ms1000000826952833

    学习了

    0

  5. 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topicName=null, topicId=null, topicList=[TopicDto(id=51728, encryptionId=974e51e2810, topicName=心血管), TopicDto(id=54248, encryptionId=737a54248f5, topicName=房颤)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210116/132afc6a1e044714a6b3389cf5203115/12b4854892844edc89f20a98098119e4.jpg, createdBy=73985436003, createdName=ms4000001286945478, createdTime=Sat Jan 16 11:46:12 CST 2021, time=2021-01-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=916898, encodeId=601d9168987a, content=学习了~, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=15e45413315, createdName=ms7000001316886289, createdTime=Fri Jan 15 14:41:53 CST 2021, time=2021-01-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=916855, encodeId=ee0e916855f3, content=口服增加可及性, beContent=null, objectType=article, channel=null, level=null, likeNumber=94, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210315/480e12f811f44bc39b347d2521d56e86/67d0e6d503124ea685205b567af3dffd.jpg, createdBy=f9435296193, createdName=Baodongxu, createdTime=Fri Jan 15 11:37:20 CST 2021, time=2021-01-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=916817, encodeId=2d8b91681eae, content=<a href='/topic/show?id=142435598f' target=_blank style='color:#2F92EE;'>#BMI#</a>BMI升高与较低的缺血性卒中、大出血风险相关。体重过轻的患者全因死亡和综合临床结局的风险较高, beContent=null, objectType=article, channel=null, level=null, likeNumber=136, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3559, encryptionId=142435598f, topicName=BMI)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200529/3611e9bb629c4e5b81fbd8ce784b06cc/128487eae357460bb98f67d86230c218.jpg, createdBy=ab235268530, 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  6. [GetPortalCommentsPageByObjectIdResponse(id=1843240, encodeId=d90b18432403c, content=<a href='/topic/show?id=3d052296e4e' target=_blank style='color:#2F92EE;'>#临床结局#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=22967, encryptionId=3d052296e4e, topicName=临床结局)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7fbd46, createdName=mei531, createdTime=Sun Apr 04 19:00:48 CST 2021, time=2021-04-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1700651, encodeId=a3091e006515e, content=<a href='/topic/show?id=822f382120a' target=_blank style='color:#2F92EE;'>#口服抗凝治疗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=38212, encryptionId=822f382120a, topicName=口服抗凝治疗)], attachment=null, authenticateStatus=null, createdAvatar=null, 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objectType=article, channel=null, level=null, likeNumber=94, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210315/480e12f811f44bc39b347d2521d56e86/67d0e6d503124ea685205b567af3dffd.jpg, createdBy=f9435296193, createdName=Baodongxu, createdTime=Fri Jan 15 11:37:20 CST 2021, time=2021-01-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=916817, encodeId=2d8b91681eae, content=<a href='/topic/show?id=142435598f' target=_blank style='color:#2F92EE;'>#BMI#</a>BMI升高与较低的缺血性卒中、大出血风险相关。体重过轻的患者全因死亡和综合临床结局的风险较高, beContent=null, objectType=article, channel=null, level=null, likeNumber=136, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3559, encryptionId=142435598f, topicName=BMI)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200529/3611e9bb629c4e5b81fbd8ce784b06cc/128487eae357460bb98f67d86230c218.jpg, createdBy=ab235268530, createdName=神盾医疗局局长Jack, createdTime=Fri Jan 15 10:03:34 CST 2021, time=2021-01-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1031343, encodeId=94561031343dc, content=房颤,临床上碰到很多哦, beContent=null, objectType=article, channel=null, level=null, likeNumber=14, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=心介, createdTime=Fri Jan 15 00:00:48 CST 2021, time=2021-01-15, status=1, ipAttribution=)]
    2021-01-16 ms4000001286945478

    谢谢分享!#心血管##房颤#

    0

  7. 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createdTime=Thu Feb 25 12:37:23 CST 2021, time=2021-02-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1614580, encodeId=7b98161458020, content=<a href='/topic/show?id=64f95426122' target=_blank style='color:#2F92EE;'>#房颤患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=54261, encryptionId=64f95426122, topicName=房颤患者)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=937e19519012, createdName=hittouch, createdTime=Sat Jan 16 12:00:48 CST 2021, time=2021-01-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=917123, encodeId=f65f91e1238f, content=谢谢分享!<a href='/topic/show?id=974e51e2810' target=_blank style='color:#2F92EE;'>#心血管#</a><a href='/topic/show?id=737a54248f5' target=_blank style='color:#2F92EE;'>#房颤#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=162, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51728, encryptionId=974e51e2810, topicName=心血管), TopicDto(id=54248, encryptionId=737a54248f5, topicName=房颤)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210116/132afc6a1e044714a6b3389cf5203115/12b4854892844edc89f20a98098119e4.jpg, createdBy=73985436003, createdName=ms4000001286945478, createdTime=Sat Jan 16 11:46:12 CST 2021, time=2021-01-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=916898, encodeId=601d9168987a, content=学习了~, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=15e45413315, createdName=ms7000001316886289, createdTime=Fri Jan 15 14:41:53 CST 2021, time=2021-01-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=916855, encodeId=ee0e916855f3, content=口服增加可及性, beContent=null, objectType=article, channel=null, level=null, likeNumber=94, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210315/480e12f811f44bc39b347d2521d56e86/67d0e6d503124ea685205b567af3dffd.jpg, createdBy=f9435296193, createdName=Baodongxu, createdTime=Fri Jan 15 11:37:20 CST 2021, time=2021-01-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=916817, encodeId=2d8b91681eae, content=<a href='/topic/show?id=142435598f' target=_blank style='color:#2F92EE;'>#BMI#</a>BMI升高与较低的缺血性卒中、大出血风险相关。体重过轻的患者全因死亡和综合临床结局的风险较高, beContent=null, objectType=article, channel=null, level=null, likeNumber=136, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3559, encryptionId=142435598f, topicName=BMI)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200529/3611e9bb629c4e5b81fbd8ce784b06cc/128487eae357460bb98f67d86230c218.jpg, createdBy=ab235268530, createdName=神盾医疗局局长Jack, createdTime=Fri Jan 15 10:03:34 CST 2021, time=2021-01-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1031343, encodeId=94561031343dc, content=房颤,临床上碰到很多哦, beContent=null, objectType=article, channel=null, level=null, likeNumber=14, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=心介, createdTime=Fri Jan 15 00:00:48 CST 2021, time=2021-01-15, status=1, ipAttribution=)]
    2021-01-15 ms7000001316886289

    学习了~

    0

  8. [GetPortalCommentsPageByObjectIdResponse(id=1843240, encodeId=d90b18432403c, content=<a href='/topic/show?id=3d052296e4e' target=_blank style='color:#2F92EE;'>#临床结局#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=22967, encryptionId=3d052296e4e, topicName=临床结局)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7fbd46, createdName=mei531, createdTime=Sun Apr 04 19:00:48 CST 2021, time=2021-04-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1700651, encodeId=a3091e006515e, content=<a href='/topic/show?id=822f382120a' target=_blank style='color:#2F92EE;'>#口服抗凝治疗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=38212, encryptionId=822f382120a, topicName=口服抗凝治疗)], attachment=null, authenticateStatus=null, createdAvatar=null, 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topicName=null, topicId=null, topicList=[TopicDto(id=51728, encryptionId=974e51e2810, topicName=心血管), TopicDto(id=54248, encryptionId=737a54248f5, topicName=房颤)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210116/132afc6a1e044714a6b3389cf5203115/12b4854892844edc89f20a98098119e4.jpg, createdBy=73985436003, createdName=ms4000001286945478, createdTime=Sat Jan 16 11:46:12 CST 2021, time=2021-01-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=916898, encodeId=601d9168987a, content=学习了~, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=15e45413315, createdName=ms7000001316886289, createdTime=Fri Jan 15 14:41:53 CST 2021, time=2021-01-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=916855, encodeId=ee0e916855f3, content=口服增加可及性, beContent=null, objectType=article, channel=null, level=null, likeNumber=94, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210315/480e12f811f44bc39b347d2521d56e86/67d0e6d503124ea685205b567af3dffd.jpg, createdBy=f9435296193, createdName=Baodongxu, createdTime=Fri Jan 15 11:37:20 CST 2021, time=2021-01-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=916817, encodeId=2d8b91681eae, content=<a href='/topic/show?id=142435598f' target=_blank style='color:#2F92EE;'>#BMI#</a>BMI升高与较低的缺血性卒中、大出血风险相关。体重过轻的患者全因死亡和综合临床结局的风险较高, beContent=null, objectType=article, channel=null, level=null, likeNumber=136, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3559, encryptionId=142435598f, topicName=BMI)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200529/3611e9bb629c4e5b81fbd8ce784b06cc/128487eae357460bb98f67d86230c218.jpg, createdBy=ab235268530, createdName=神盾医疗局局长Jack, createdTime=Fri Jan 15 10:03:34 CST 2021, time=2021-01-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1031343, encodeId=94561031343dc, content=房颤,临床上碰到很多哦, beContent=null, objectType=article, channel=null, level=null, likeNumber=14, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=心介, createdTime=Fri Jan 15 00:00:48 CST 2021, time=2021-01-15, status=1, ipAttribution=)]
    2021-01-15 Baodongxu

    口服增加可及性

    0

  9. 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objectType=article, channel=null, level=null, likeNumber=94, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210315/480e12f811f44bc39b347d2521d56e86/67d0e6d503124ea685205b567af3dffd.jpg, createdBy=f9435296193, createdName=Baodongxu, createdTime=Fri Jan 15 11:37:20 CST 2021, time=2021-01-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=916817, encodeId=2d8b91681eae, content=<a href='/topic/show?id=142435598f' target=_blank style='color:#2F92EE;'>#BMI#</a>BMI升高与较低的缺血性卒中、大出血风险相关。体重过轻的患者全因死亡和综合临床结局的风险较高, beContent=null, objectType=article, channel=null, level=null, likeNumber=136, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3559, encryptionId=142435598f, topicName=BMI)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200529/3611e9bb629c4e5b81fbd8ce784b06cc/128487eae357460bb98f67d86230c218.jpg, createdBy=ab235268530, createdName=神盾医疗局局长Jack, createdTime=Fri Jan 15 10:03:34 CST 2021, time=2021-01-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1031343, encodeId=94561031343dc, content=房颤,临床上碰到很多哦, beContent=null, objectType=article, channel=null, level=null, likeNumber=14, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=心介, createdTime=Fri Jan 15 00:00:48 CST 2021, time=2021-01-15, status=1, ipAttribution=)]
    2021-01-15 神盾医疗局局长Jack

    #BMI#BMI升高与较低的缺血性卒中、大出血风险相关。体重过轻的患者全因死亡和综合临床结局的风险较高

    0

  10. 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objectType=article, channel=null, level=null, likeNumber=94, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210315/480e12f811f44bc39b347d2521d56e86/67d0e6d503124ea685205b567af3dffd.jpg, createdBy=f9435296193, createdName=Baodongxu, createdTime=Fri Jan 15 11:37:20 CST 2021, time=2021-01-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=916817, encodeId=2d8b91681eae, content=<a href='/topic/show?id=142435598f' target=_blank style='color:#2F92EE;'>#BMI#</a>BMI升高与较低的缺血性卒中、大出血风险相关。体重过轻的患者全因死亡和综合临床结局的风险较高, beContent=null, objectType=article, channel=null, level=null, likeNumber=136, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3559, encryptionId=142435598f, topicName=BMI)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200529/3611e9bb629c4e5b81fbd8ce784b06cc/128487eae357460bb98f67d86230c218.jpg, createdBy=ab235268530, createdName=神盾医疗局局长Jack, createdTime=Fri Jan 15 10:03:34 CST 2021, time=2021-01-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1031343, encodeId=94561031343dc, content=房颤,临床上碰到很多哦, beContent=null, objectType=article, channel=null, level=null, likeNumber=14, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=心介, createdTime=Fri Jan 15 00:00:48 CST 2021, time=2021-01-15, status=1, ipAttribution=)]
    2021-01-15 心介

    房颤,临床上碰到很多哦

    0

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JCO:造血细胞移植后发生房颤的风险及相关因素

造血细胞移植(HCT)是多种血液疾病的有效治疗方法。在过去50年里,HCT方案的改进极大改善了众多患者的存活预后。

王建安教授:从房颤患者的卒中预防,看LAAC的未来发展

在我国人口老龄化进程不断加速的今天,心脑血管疾病发病率的上升趋势给社会及家庭带来了沉重负担;房颤作为临床中最常见的心律失常,大大增加了患者罹患卒中的几率。

JAHA:种族、体重指数与房颤风险

肥胖与房颤发生风险增加有关,但体重指数与房颤风险之间的关系呈J型,并且这种关系因人种而异,因此,BMI较高的美籍华裔参与者的房颤风险增加更为明显,而黑人参与者的风险增加最小。

Annals of Neurology :房颤提前口服抗凝,有助于降低脑中风严重性,改善溶栓预后

房颤提前口服抗凝,有助于降低脑中风严重性,改善溶栓预后

Hypertension:房颤患者血压与脑损伤的关系

在房颤患者中,BP与白质病变及其程度密切相关,但与大的非皮质或皮质梗塞无关。

JAHA:9-癸烯酰肉碱与房颤有关

这项非靶向代谢组学分析发现了一种新的参与房颤发生的生物标记物9-癸烯酰肉碱,但这种乙酰肉碱可能与房颤没有因果关系。