European Heart Journal :拥有更健康的心脏,认知能力更强!

2021-05-14 网络 网络

心血管疾病和认知障碍是日益严重的公共健康问题,特别是在全球老龄化人口国家中。

血管疾病和认知障碍是日益严重的公共健康问题,特别是在全球老龄化人口国家中。

之前的研究工作表明,心脑器官系统之间存在相互作用。事实上,心脏代谢性疾病与认知能力的加速下降有关,而对其进行治疗则可减缓痴呆症的进展。

然而,人们对心血管疾病和危险因素导致认知障碍的确切机制并不完全了解,

因此探讨心血管结构与认知表现之间的关系可能为心血管疾病导致认知障碍的潜在机制提供新的见解。

近期,一项发表在在《欧洲心脏杂志心血管成像》( European Heart Journal )上的研究表明具有健康的心脏结构和功能的人具有更好的认知功能

在这项研究中研究员研究了英国32,000多名生物库参与者的心脏健康与认知功能之间的联系。该团队使用从MRI扫描获得的解剖结构和功能评估心脏健康。使用流体智力(FI,13个言语数字推理问题)和反应时间(RT,定时配对练习)的测试来评估认知功能。

纳入分析的英国生物库参与者的流程图。

CMR,心血管磁共振;FI,流体智力;RT,反应时间

 研究包括以下CMR指标:舒张末期和收缩末期的左、右心室((LV and RV) 容积,左、右心室射血分数,左、右心室搏出量,左心室质量和主动脉扩张性。

为了研究观察到的关系的潜在机制,研究小组调整了年龄、性别、吸烟、教育、贫困、糖尿病、高血压、高胆固醇、以前的心肌梗死、酒精摄入和运动水平潜在混杂因素。

研究结果发现,在这个主要是健康的队列中(平均年龄63.0±7.5岁),较好的认知表现(较高的FI,较低的RT)与较大的LV/RV容积、较高的LV/RV卒中容积、较大的LV质量有关

在完全调整的模型中,较好的认知表现(较高的FI,较低的RT)与较大的LV/RV容积、较高的LV/RV卒中容积、较大的LV质量以及较大的主动脉扩张性有关。

综上,更健康的的心血管表型与更好的认知表现有关,因此,保护我们的心血管,就是爱护我们的大脑。

这项研究发现支持了心血管和认知健康之间的联系,并提出了对相关疾病结果进行跨系统风险评估的理论依据。

参考文献:

Associations of cognitive performance with cardiovascular magnetic resonance phenotypes in the UK Biobank

 

 

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (5)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1728949, encodeId=75a51e28949ba, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Tue May 25 07:45:34 CST 2021, time=2021-05-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1357707, encodeId=bfde135e7075e, content=<a href='/topic/show?id=b0702e84b9' target=_blank style='color:#2F92EE;'>#ART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2784, encryptionId=b0702e84b9, topicName=ART)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Sun May 16 14:45:34 CST 2021, time=2021-05-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1563457, encodeId=7fe8156345e1c, content=<a href='/topic/show?id=f69d864413' target=_blank style='color:#2F92EE;'>#HEART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8644, encryptionId=f69d864413, topicName=HEART)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=80d715270048, createdName=slcumt, createdTime=Sun May 16 14:45:34 CST 2021, time=2021-05-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=965815, encodeId=e2ab96581512, content=学, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210319/11a5cd980a9d460da3309d2f9b731d89/6bc10897e4c7451ab7a1b02b57b06c50.jpg, createdBy=9c9c2261743, createdName=12186752m54暂无昵称, createdTime=Sat May 15 12:28:37 CST 2021, time=2021-05-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=965751, encodeId=9ebd965e51d9, content=心智合一,互为因果, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b7a31928393, createdName=学医无涯, createdTime=Sat May 15 07:47:23 CST 2021, time=2021-05-15, status=1, ipAttribution=)]
    2021-05-25 feather89
  2. [GetPortalCommentsPageByObjectIdResponse(id=1728949, encodeId=75a51e28949ba, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Tue May 25 07:45:34 CST 2021, time=2021-05-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1357707, encodeId=bfde135e7075e, content=<a href='/topic/show?id=b0702e84b9' target=_blank style='color:#2F92EE;'>#ART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2784, encryptionId=b0702e84b9, topicName=ART)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Sun May 16 14:45:34 CST 2021, time=2021-05-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1563457, encodeId=7fe8156345e1c, content=<a href='/topic/show?id=f69d864413' target=_blank style='color:#2F92EE;'>#HEART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8644, encryptionId=f69d864413, topicName=HEART)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=80d715270048, createdName=slcumt, createdTime=Sun May 16 14:45:34 CST 2021, time=2021-05-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=965815, encodeId=e2ab96581512, content=学, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210319/11a5cd980a9d460da3309d2f9b731d89/6bc10897e4c7451ab7a1b02b57b06c50.jpg, createdBy=9c9c2261743, createdName=12186752m54暂无昵称, createdTime=Sat May 15 12:28:37 CST 2021, time=2021-05-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=965751, encodeId=9ebd965e51d9, content=心智合一,互为因果, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b7a31928393, createdName=学医无涯, createdTime=Sat May 15 07:47:23 CST 2021, time=2021-05-15, status=1, ipAttribution=)]
    2021-05-16 zhaojie88
  3. [GetPortalCommentsPageByObjectIdResponse(id=1728949, encodeId=75a51e28949ba, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Tue May 25 07:45:34 CST 2021, time=2021-05-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1357707, encodeId=bfde135e7075e, content=<a href='/topic/show?id=b0702e84b9' target=_blank style='color:#2F92EE;'>#ART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2784, encryptionId=b0702e84b9, topicName=ART)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Sun May 16 14:45:34 CST 2021, time=2021-05-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1563457, encodeId=7fe8156345e1c, content=<a href='/topic/show?id=f69d864413' target=_blank style='color:#2F92EE;'>#HEART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8644, encryptionId=f69d864413, topicName=HEART)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=80d715270048, createdName=slcumt, createdTime=Sun May 16 14:45:34 CST 2021, time=2021-05-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=965815, encodeId=e2ab96581512, content=学, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210319/11a5cd980a9d460da3309d2f9b731d89/6bc10897e4c7451ab7a1b02b57b06c50.jpg, createdBy=9c9c2261743, createdName=12186752m54暂无昵称, createdTime=Sat May 15 12:28:37 CST 2021, time=2021-05-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=965751, encodeId=9ebd965e51d9, content=心智合一,互为因果, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b7a31928393, createdName=学医无涯, createdTime=Sat May 15 07:47:23 CST 2021, time=2021-05-15, status=1, ipAttribution=)]
    2021-05-16 slcumt
  4. [GetPortalCommentsPageByObjectIdResponse(id=1728949, encodeId=75a51e28949ba, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Tue May 25 07:45:34 CST 2021, time=2021-05-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1357707, encodeId=bfde135e7075e, content=<a href='/topic/show?id=b0702e84b9' target=_blank style='color:#2F92EE;'>#ART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2784, encryptionId=b0702e84b9, topicName=ART)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Sun May 16 14:45:34 CST 2021, time=2021-05-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1563457, encodeId=7fe8156345e1c, content=<a href='/topic/show?id=f69d864413' target=_blank style='color:#2F92EE;'>#HEART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8644, encryptionId=f69d864413, topicName=HEART)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=80d715270048, createdName=slcumt, createdTime=Sun May 16 14:45:34 CST 2021, time=2021-05-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=965815, encodeId=e2ab96581512, content=学, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210319/11a5cd980a9d460da3309d2f9b731d89/6bc10897e4c7451ab7a1b02b57b06c50.jpg, createdBy=9c9c2261743, createdName=12186752m54暂无昵称, createdTime=Sat May 15 12:28:37 CST 2021, time=2021-05-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=965751, encodeId=9ebd965e51d9, content=心智合一,互为因果, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b7a31928393, createdName=学医无涯, createdTime=Sat May 15 07:47:23 CST 2021, time=2021-05-15, status=1, ipAttribution=)]
    2021-05-15 12186752m54暂无昵称

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=1728949, encodeId=75a51e28949ba, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Tue May 25 07:45:34 CST 2021, time=2021-05-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1357707, encodeId=bfde135e7075e, content=<a href='/topic/show?id=b0702e84b9' target=_blank style='color:#2F92EE;'>#ART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2784, encryptionId=b0702e84b9, topicName=ART)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Sun May 16 14:45:34 CST 2021, time=2021-05-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1563457, encodeId=7fe8156345e1c, content=<a href='/topic/show?id=f69d864413' target=_blank style='color:#2F92EE;'>#HEART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8644, encryptionId=f69d864413, topicName=HEART)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=80d715270048, createdName=slcumt, createdTime=Sun May 16 14:45:34 CST 2021, time=2021-05-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=965815, encodeId=e2ab96581512, content=学, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210319/11a5cd980a9d460da3309d2f9b731d89/6bc10897e4c7451ab7a1b02b57b06c50.jpg, createdBy=9c9c2261743, createdName=12186752m54暂无昵称, createdTime=Sat May 15 12:28:37 CST 2021, time=2021-05-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=965751, encodeId=9ebd965e51d9, content=心智合一,互为因果, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b7a31928393, createdName=学医无涯, createdTime=Sat May 15 07:47:23 CST 2021, time=2021-05-15, status=1, ipAttribution=)]
    2021-05-15 学医无涯

    心智合一,互为因果

    0