ARCH PATHOL LAB MED:计算机断层引导下经皮肺穿刺细针穿刺细胞学检查

2020-04-05 MedSci原创 MedSci原创

肺结节细针穿刺细胞学检查(FNAC)通常由计算机断层扫描(CT)引导,而超声检查(US)通常被认为不适用于此项操作。本研究评价超声引导下经胸FNAC对周围性肺结节的临床适用性和诊断价值。

肺结节细针穿刺细胞学检查(FNAC)通常由计算机断层扫描(CT)引导,而超声检查(US)通常被认为不适用于此项操作。本研究评价超声引导下经胸FNAC对周围性肺结节的临床适用性和诊断价值。

研究人员对40名患者超声引导下经胸FNAC,患者有周围型、胸膜下型和椎旁型肺结节。用风干和Diff-Quik染色的涂片进行快速现场评价;另外的涂片用酒精固定,用于Papanicolaou染色。 建立细胞块进行免疫细胞化学和分子研究;在2例中,还进行了流式细胞术评估。本研究与40例ct引导下的胸膜、外周和椎旁肺结节患者的肺FNAC样本进行比较,以评估在诊断率、手术时间、安全性和成本方面的差异。

在95%的病例中,美国指导的FNAC样本的结果是足够的和有代表性的。 两组在涂片和细胞块的诊断率、通过数和细胞性方面无显着性差异。 执行美国制导FNAC的平均时间为13.1分钟,而CT制导FNAC的平均时间为23.6分钟。 因此,美国引导的FNAC明显比CT引导的肺FNAC更快。因为在接受US引导的FNAC的1个人和接受CT引导的FNAC的9个人中气胸发生,我们可能得出结论,美国引导的FNAC是一个明显安全的程序。 最后,比较这两种程序的成本,美国引导的FNAC更便宜。

我们的经验表明,超声引导下经胸FNAC对选定的肺结节具有更高的临床适用性和诊断价值。

原始出处:

Immacolata Cozzolino, MD, PhD; Andrea Ronchi, MD; Adequacy of Cytologic Samples by Ultrasound-Guided Percutaneous Transthoracic Fine-Needle Aspiration Cytology of Peripheral Pulmonary Nodules for Morphologic Diagnosis and Molecular Evaluations: Comparison

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    2021-03-02 yb6560
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    2021-01-11 bioon14
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    2020-04-07 仁医06
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    2020-04-07 智慧医人