Polymers:形状记忆聚合物支架可减少血管再狭窄的发生风险

2020-11-07 MedSci原创 MedSci原创

形状记忆聚合物(SMPs)因其良好的生物相容性和生物降解性而在生物医学领域广受关注。形状记忆聚合物支架在治疗血管堵塞方面的可行性已得到了验证。然而,SMP支架的实际应用仍处于起步阶段。为了提高SMP支

形状记忆聚合物(SMPs)因其良好的生物相容性和生物降解性而在生物医学领域广受关注。形状记忆聚合物支架在治疗血管堵塞方面的可行性已得到了验证。然而,SMP支架的实际应用仍处于起步阶段。为了提高SMP支架的机械性能,本研究提出了一种基于超材料的新几何模型。

为了验证这种支架的可行性和力学行为,对SMP支架的屈曲分析和体内膨胀性能进行了模拟。数值结果表明,较小半径的支架具有较高的临界弯曲载荷和较小的弯曲位移。此外,与传统支架相比,SMP支架与血管的接触面积更小,植入应力更小。这表明,这种SMP支架的属性是减少血管再狭窄。

为了表征SMP支架的径向强度,通过假设支架的变形主要由弯曲和拉伸组成,得出了一个分析方案。对SMP支架的径向强度以径向力的形式进行评估。分析结果表明,支架的径向强度取决于支架的半径和圆周方向的单位单元周期数。

 

原始出处:

 

Ruoxuan LiuShuai Xu, et al., Theoretical and Numerical Analysis of Mechanical Behaviors of a Metamaterial-Based Shape Memory Polymer Stent. Polymers (Basel). 2020 Aug 10;12(8):1784. doi: 10.3390/polym12081784.

 

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    2021-05-24 anminleiryan
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    2020-11-28 zhouqu_8
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    2020-11-09 yese
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    2020-11-07 147d246em28暂无昵称

    值得学习!

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