J Gastroenterology:胃切除术后残胃中使用内镜黏膜下剥离术治疗早期胃癌的近期和远期疗效分析

2018-11-11 MedSci MedSci原创

胃切除术后的残胃中的早期胃癌(EGC)的内镜黏膜下剥离术(ESD)是一种微创治疗方法。本研究旨在阐明ESD对残余胃中EGC的短期和长期结果。

背景
切除术后的残中的早期胃癌(EGC)的内镜黏膜下剥离术(ESD)是一种微创治疗方法。本研究旨在阐明ESD对残余胃中EGC的短期和长期结果。

方法
研究人员回顾性分析了2002年9月至2016年3月期间在接受ESD治疗的患者,并检索临床病理学数据以评估整块切除率,并发症和长期结果,包括总生存率和特异性生存率。

结果
研究人员共回顾性分析了136例患者,其中共有165例病灶,共进行了157例ESD治疗。整块切除率为95.5%。并发症包括:16例术中穿孔(10.2%),2例延迟穿孔(1.3%)和15例延迟出血(9.6%),最后均经内镜成功治疗。缝合线组(100%)和非吻合线或缝合线组(98.8%)的整块切除率显着高于吻合组(82.9%)。然而,吻合组术中穿孔率(31.4%)显着高于其他组。在50.7个月的中位随访期间(四分位数范围30.8-91.3),5年总体和原因特异性存活率分别为88.4%和97.6%。

结论
EGC在残胃中的治疗效果长期来看效果是有效的。然而,由于整块切除率低和穿孔率高,涉及吻合术的ESD是技术要求严格的手术方式。


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content=<a href='/topic/show?id=7730e85412' target=_blank style='color:#2F92EE;'>#Gastroenterology#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7854, encryptionId=7730e85412, topicName=Gastroenterology)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=5fc29706655, createdName=chaojitidian, createdTime=Tue Nov 13 12:07:00 CST 2018, time=2018-11-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1518570, encodeId=a7c415185e01d, content=<a href='/topic/show?id=324183166ad' target=_blank style='color:#2F92EE;'>#胃切除#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83166, encryptionId=324183166ad, topicName=胃切除)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e3cc11160823, createdName=bshuang, createdTime=Tue Nov 13 12:07:00 CST 2018, time=2018-11-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1520011, encodeId=9301152001182, content=<a href='/topic/show?id=6ab11032506f' target=_blank style='color:#2F92EE;'>#黏膜#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=103250, encryptionId=6ab11032506f, topicName=黏膜)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=057f11309297, createdName=snowpeakxu, createdTime=Tue Nov 13 12:07:00 CST 2018, time=2018-11-13, status=1, ipAttribution=)]
  5. [GetPortalCommentsPageByObjectIdResponse(id=1877083, encodeId=b9f618e7083f9, content=<a href='/topic/show?id=67c5319121e' target=_blank style='color:#2F92EE;'>#切除术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=31912, encryptionId=67c5319121e, topicName=切除术)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=9d8a96, createdName=doctorzheng, createdTime=Sun Jun 30 11:07:00 CST 2019, time=2019-06-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2064538, encodeId=4da92064538e7, content=<a href='/topic/show?id=94ffe853a7' target=_blank style='color:#2F92EE;'>#Gastroenterol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7853, encryptionId=94ffe853a7, topicName=Gastroenterol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0bed488, createdName=jktdtl, createdTime=Sat Jun 01 00:07:00 CST 2019, time=2019-06-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1711712, encodeId=54941e11712f5, content=<a href='/topic/show?id=9a1c289680' target=_blank style='color:#2F92EE;'>#AST#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2896, encryptionId=9a1c289680, topicName=AST)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8b9831894722, createdName=ms24272190615788285182, createdTime=Sun Feb 10 17:07:00 CST 2019, time=2019-02-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1647222, encodeId=b2c3164e222e0, content=<a href='/topic/show?id=e9bae04003f' target=_blank style='color:#2F92EE;'>#疗效分析#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, 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beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7846, encryptionId=9d4ee84647, topicName=GAS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e2dd327, createdName=许安, createdTime=Wed Dec 05 22:07:00 CST 2018, time=2018-12-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1262024, encodeId=a4581262024b2, content=<a href='/topic/show?id=0ceb30545e0' target=_blank style='color:#2F92EE;'>#内镜#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=30545, encryptionId=0ceb30545e0, topicName=内镜)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c30265, createdName=jiafufeng@yaho, createdTime=Tue Nov 13 12:07:00 CST 2018, time=2018-11-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1504521, encodeId=4de21504521bd, content=<a href='/topic/show?id=7730e85412' target=_blank style='color:#2F92EE;'>#Gastroenterology#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7854, encryptionId=7730e85412, topicName=Gastroenterology)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=5fc29706655, createdName=chaojitidian, createdTime=Tue Nov 13 12:07:00 CST 2018, time=2018-11-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1518570, encodeId=a7c415185e01d, content=<a href='/topic/show?id=324183166ad' target=_blank style='color:#2F92EE;'>#胃切除#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83166, encryptionId=324183166ad, topicName=胃切除)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e3cc11160823, createdName=bshuang, createdTime=Tue Nov 13 12:07:00 CST 2018, time=2018-11-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1520011, encodeId=9301152001182, content=<a href='/topic/show?id=6ab11032506f' target=_blank style='color:#2F92EE;'>#黏膜#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=103250, encryptionId=6ab11032506f, topicName=黏膜)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=057f11309297, createdName=snowpeakxu, createdTime=Tue Nov 13 12:07:00 CST 2018, time=2018-11-13, status=1, ipAttribution=)]
  6. [GetPortalCommentsPageByObjectIdResponse(id=1877083, encodeId=b9f618e7083f9, content=<a href='/topic/show?id=67c5319121e' target=_blank style='color:#2F92EE;'>#切除术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=31912, encryptionId=67c5319121e, topicName=切除术)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=9d8a96, createdName=doctorzheng, createdTime=Sun Jun 30 11:07:00 CST 2019, time=2019-06-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2064538, encodeId=4da92064538e7, content=<a href='/topic/show?id=94ffe853a7' target=_blank style='color:#2F92EE;'>#Gastroenterol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7853, encryptionId=94ffe853a7, topicName=Gastroenterol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0bed488, createdName=jktdtl, createdTime=Sat Jun 01 00:07:00 CST 2019, time=2019-06-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1711712, encodeId=54941e11712f5, content=<a href='/topic/show?id=9a1c289680' target=_blank style='color:#2F92EE;'>#AST#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2896, encryptionId=9a1c289680, topicName=AST)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8b9831894722, createdName=ms24272190615788285182, createdTime=Sun Feb 10 17:07:00 CST 2019, time=2019-02-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1647222, encodeId=b2c3164e222e0, content=<a href='/topic/show?id=e9bae04003f' target=_blank style='color:#2F92EE;'>#疗效分析#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, 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beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7846, encryptionId=9d4ee84647, topicName=GAS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e2dd327, createdName=许安, createdTime=Wed Dec 05 22:07:00 CST 2018, time=2018-12-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1262024, encodeId=a4581262024b2, content=<a href='/topic/show?id=0ceb30545e0' target=_blank style='color:#2F92EE;'>#内镜#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=30545, encryptionId=0ceb30545e0, topicName=内镜)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c30265, createdName=jiafufeng@yaho, createdTime=Tue Nov 13 12:07:00 CST 2018, time=2018-11-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1504521, encodeId=4de21504521bd, content=<a href='/topic/show?id=7730e85412' target=_blank style='color:#2F92EE;'>#Gastroenterology#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7854, encryptionId=7730e85412, topicName=Gastroenterology)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=5fc29706655, createdName=chaojitidian, createdTime=Tue Nov 13 12:07:00 CST 2018, time=2018-11-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1518570, encodeId=a7c415185e01d, content=<a href='/topic/show?id=324183166ad' target=_blank style='color:#2F92EE;'>#胃切除#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83166, encryptionId=324183166ad, topicName=胃切除)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e3cc11160823, createdName=bshuang, createdTime=Tue Nov 13 12:07:00 CST 2018, time=2018-11-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1520011, encodeId=9301152001182, content=<a href='/topic/show?id=6ab11032506f' target=_blank style='color:#2F92EE;'>#黏膜#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=103250, encryptionId=6ab11032506f, topicName=黏膜)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=057f11309297, createdName=snowpeakxu, createdTime=Tue Nov 13 12:07:00 CST 2018, time=2018-11-13, status=1, ipAttribution=)]
    2018-12-05 许安
  7. 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    2018-11-13 bshuang
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    2018-11-13 snowpeakxu

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内镜黏膜下剥离术(ESD)已广泛用于治疗浅表性食管鳞状细胞癌(SESCC)。然而,SESCC接受ESD手术和食管切除术的长期结果目前还没有研究进行报道。因此,研究人员进行了队列研究以探讨ESD和食管切除术的临床结果差异。

Endoscopy:内镜下切除壶腹部乳头与传统的壶腹部腺瘤大面积清除术疗效相同

壶腹腺瘤的内镜下切除术是外科手术治疗的安全有效的替代方法。而如果患者壶腹部乳头Vateri(LSL-P)有较大的横向扩散病变,则需通过手术治疗。内镜下切除LSL-P的数据及效果十分有限。本研究的目的是比较LSL-P的内镜下切除与标准壶腹部腺瘤手术的效果。

Dig Dis & Sci:内窥镜逆行胰胆管造影术对长期行血液透析的患者发生胆管结石的影响分析

前期的研究评估了行血液透析的终末期肾病(ESRD)患者行内镜逆行胰胆管造影术(ERCP)的安全性,结果表明术后出血风险增加。本项研究调查了ERCP治疗ESRD长期透析患者的胆总管结石的安全性和有效性。